Cryo-EM structure of Chikungunya virus asymmetric unit
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8fcg
Q-score: 0.518
Chmielewski D, Su GC, Kaelber JT, Pintilie GD, Chen M, Jin J, Auguste AJ, Chiu W
Pnas Nexus (2024) 3 pp. pgae102-pgae102 [ Pubmed: 38525304 DOI: doi:10.1093/pnasnexus/pgae102 ]
- E2 glycoprotein (47 kDa, Protein from Chikungunya virus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Chikungunya virus (500 kDa, Virus from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 8ewf
Q-score: 0.321
Zimmerman O, Zimmerman MI, Nelson CA, Raju S, Errico JM, Madden EA, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Earnest JT, Holmes AC, Ebel GD, Zmasek C, Scheuermann RH, Fremont DH, Diamond MS
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Chikungunya virus vlp in complex with a chimeric mxra8 receptor (avian d1 with mammalian d2) (495 MDa, Complex from Chikungunya virus)
- Spike glycoprotein e2 (46 kDa, Protein from Chikungunya virus)
- E1 envelope protein (47 kDa, Protein from Chikungunya virus)
- Chimeric mxra8 receptor: d1 from duck mxra8 and d2 from mouse mxra8 (30 kDa, Protein from Anas platyrhynchos)
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 7cvy
Q-score: 0.178
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab heavy chain (23 kDa, Protein from Mus musculus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab region of chk-124 (Cellular component from Mus musculus)
- Chikungunya virus in complex with fab fragments of mab chk-124 (Complex)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7cvz
Q-score: 0.281
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Fab light chain (23 kDa, Protein from Mus musculus)
- Chk-263 fab (Cellular component from Mus musculus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Chikungunya virus in complex with fab fragments of mab chk-263 (Complex)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7cw0
Q-score: 0.184
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus in complex with mab chk-263 igg (Complex)
- Fab region of chk-263 (Cellular component from Mus musculus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7cw2
Q-score: 0.316
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Chikungunya virus (Cellular component from Chikungunya virus)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Fab region of chk-263 (Cellular component from Mus musculus)
- Localized reconstruction of subregions around the icosahedral 5-fold vertex of chikv:chk-263 fab complex (Complex)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 7cw3
Q-score: 0.117
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Fab region of chk-263 igg (Complex)
- Chikungunya virus (Complex from Mus musculus)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Subregions around the icosahedral 2-fold vertex of chikungunya virus in complexed with chk-263 igg (Complex from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w09
Q-score: 0.34
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Chikungunya virus (Virus from Chikungunya virus)
- E1 glycoprotein (42 kDa, Protein from Chikungunya virus)
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Chikungunya virus-fab complex (Complex)
- E3 (6 kDa, Protein from Chikungunya virus)
- E2 glycoprotein (38 kDa, Protein from Chikungunya virus)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
Electron Cryo-Microscopy Of Chikungunya VLP
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 6nk5
Q-score: 0.304
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell (2019) 177 pp. 1725- [ Pubmed: 31080061 DOI: doi:10.1016/j.cell.2019.04.006 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Chikungunya virus (Virus from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus (strain 37997))
- Capsid protein (16 kDa, Protein from Chikungunya virus (strain 37997))
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus (strain 37997))
Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
Resolution: 4.99 Å
EM Method: Single-particle
Fitted PDBs: 6nk7
Q-score: 0.205
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell (2019) 177 pp. 1725- [ Pubmed: 31080061 DOI: doi:10.1016/j.cell.2019.04.006 ]
- Chikungunya virus with mxra8 receptor (Complex)
- Mouse mxra8 receptor ectodomain (Complex from Mus musculus)
- Matrix remodeling-associated protein 8 (30 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- E2 glycoprotein (47 kDa, Protein from Chikungunya virus)
- E3 glycoprotein (6 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Complex from Chikungunya virus)