48-nm doublet microtubule from Tetrahymena thermophila strain MEC17
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8sf7
Q-score: 0.206
Yang SK, Kubo S, Black CS, Peri K, Dai D, Legal T, Valente-Paterno M, Gaertig J, Bui KH
eLife (2024) 12 [ DOI: doi:10.7554/eLife.92219 Pubmed: 38598282 ]
- Cilia- and flagella-associated protein 52 (73 kDa, Protein from Tetrahymena thermophila)
- Rib27b (26 kDa, Protein from Tetrahymena thermophila)
- Cfap127 (55 kDa, Protein from Tetrahymena thermophila)
- Cfap129 (31 kDa, Protein from Tetrahymena thermophila)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Flagellar microtugule protofilament ribbon protein (72 kDa, Protein from Tetrahymena thermophila)
- Tubulin beta chain (49 kDa, Protein from Tetrahymena thermophila)
- Nebulin (61 kDa, Protein from Tetrahymena thermophila)
- Parkin co-regulated protein pacrga (36 kDa, Protein from Tetrahymena thermophila)
- Cfap115 (110 kDa, Protein from Tetrahymena thermophila)
- Cfap182a (20 kDa, Protein from Tetrahymena thermophila)
- Rib43a protein (17 kDa, Protein from Tetrahymena thermophila)
- Rib72b (60 kDa, Protein from Tetrahymena thermophila)
- Rib38 (38 kDa, Protein from Tetrahymena thermophila)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha chain (49 kDa, Protein from Tetrahymena thermophila)
- Cfap112a (30 kDa, Protein from Tetrahymena thermophila)
- Stpg1a (42 kDa, Protein from Tetrahymena thermophila)
- Cfap107 (21 kDa, Protein from Tetrahymena thermophila)
- Rib22 (22 kDa, Protein from Tetrahymena thermophila)
- Cfap182b (11 kDa, Protein from Tetrahymena thermophila)
- Dna polymerase delta c4-type zinc-finger protein (31 kDa, Protein from Tetrahymena thermophila)
- Protofilament ribbon protein (34 kDa, Protein from Tetrahymena thermophila)
- Flagellar flij protein (12 kDa, Protein from Tetrahymena thermophila)
- Cfap20 (22 kDa, Protein from Tetrahymena thermophila)
- Cilia- and flagella-associated protein 53 (60 kDa, Protein from Tetrahymena thermophila)
- Oj3 (19 kDa, Protein from Tetrahymena thermophila)
- Cfap21a (48 kDa, Protein from Tetrahymena thermophila)
- Cilia- and flagella-associated protein 45 (59 kDa, Protein from Tetrahymena thermophila)
- Magnesium ion (24 Da, Ligand)
- Ij34 (34 kDa, Protein from Tetrahymena thermophila)
- Cfam166a (25 kDa, Protein from Tetrahymena thermophila)
- Rib26 (26 kDa, Protein from Tetrahymena thermophila)
- Stpg2 (33 kDa, Protein from Tetrahymena thermophila)
- Cfap112b (32 kDa, Protein from Tetrahymena thermophila)
- Cfam166c (25 kDa, Protein from Tetrahymena thermophila)
- Oj2 (19 kDa, Protein from Tetrahymena thermophila)
- Sb1 (17 kDa, Protein from Tetrahymena thermophila)
- Cfam166b (17 kDa, Protein from Tetrahymena thermophila)
- Rib27a (27 kDa, Protein from Tetrahymena thermophila)
- Nucleoside diphosphate kinase (42 kDa, Protein from Tetrahymena thermophila)
- Cfap210 (61 kDa, Protein from Tetrahymena thermophila)
- Cfap77a (28 kDa, Protein from Tetrahymena thermophila)
- Rib57 (57 kDa, Protein from Tetrahymena thermophila)
- 48-nm repeat unit of microtubule doublet from tetrahymena thermophila strain mec17 (7 MDa, Cellular component from Tetrahymena thermophila)
- Parkin co-regulated protein pacrgb (28 kDa, Protein from Tetrahymena thermophila)
- Cfap161a (57 kDa, Protein from Tetrahymena thermophila)
- Rib35 (34 kDa, Protein from Tetrahymena thermophila)
- Cfap143 (30 kDa, Protein from Tetrahymena thermophila)
Structure of LARP7 protein p65-telomerase RNA complex in telomerase
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8gap
Q-score: 0.323
Wang Y, He Y, Wang Y, Yang Y, Singh M, Eichhorn CD, Cheng X, Jiang YX, Zhou ZH, Feigon J
J Mol Biol (2023) 435 pp. 168044-168044 [ Pubmed: 37330293 DOI: doi:10.1016/j.jmb.2023.168044 ]
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (9 kDa, DNA from synthetic construct)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
base module state 1 of Tetrahymena IFT-A
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8hmc
Q-score: 0.414
Ma Y, He J, Li S, Yao D, Huang C, Wu J, Lei M
Nat Commun (2023) 14 pp. 1506-1506 [ Pubmed: 36932088 DOI: doi:10.1038/s41467-023-37208-2 ]
- Zinc ion (65 Da, Ligand)
- Wd40 repeat protein (138 kDa, Protein from Tetrahymena thermophila)
- Intraflagellar transport protein 43 homolog (16 kDa, Protein from Tetrahymena thermophila)
- Tetratricopeptide repeat protein (154 kDa, Protein from Tetrahymena thermophila)
- Intraflagellar transport protein 122 homolog (143 kDa, Protein from Tetrahymena thermophila)
- Ift-a_base-1 (Complex from Tetrahymena thermophila)
base module state 2 of Tetrahymena IFT-A
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 8hmd
Q-score: 0.197
Ma Y, He J, Li S, Yao D, Huang C, Wu J, Lei M
Nat Commun (2023) 14 pp. 1506-1506 [ Pubmed: 36932088 DOI: doi:10.1038/s41467-023-37208-2 ]
- Zinc ion (65 Da, Ligand)
- Ift-a_base-2 (Complex from Tetrahymena thermophila)
- Wd40 repeat protein (138 kDa, Protein from Tetrahymena thermophila)
- Intraflagellar transport protein 43 homolog (16 kDa, Protein from Tetrahymena thermophila)
- Tetratricopeptide repeat protein (154 kDa, Protein from Tetrahymena thermophila)
- Intraflagellar transport protein 122 homolog (143 kDa, Protein from Tetrahymena thermophila)
head module state 1 of Tetrahymena IFT-A
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8hme
Q-score: 0.247
Ma Y, He J, Li S, Yao D, Huang C, Wu J, Lei M
Nat Commun (2023) 14 pp. 1506-1506 [ Pubmed: 36932088 DOI: doi:10.1038/s41467-023-37208-2 ]
- Zinc ion (65 Da, Ligand)
- Intraflagellar transporter (161 kDa, Protein from Tetrahymena thermophila)
- Wd40 repeat protein (158 kDa, Protein from Tetrahymena thermophila)
- Ift-a_head-1 (Complex from Tetrahymena thermophila)
- Intraflagellar transport protein 122 homolog (143 kDa, Protein from Tetrahymena thermophila)
head module state 2 of Tetrahymena IFT-A
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 8hmf
Q-score: 0.199
Ma Y, He J, Li S, Yao D, Huang C, Wu J, Lei M
Nat Commun (2023) 14 pp. 1506-1506 [ Pubmed: 36932088 DOI: doi:10.1038/s41467-023-37208-2 ]
- Zinc ion (65 Da, Ligand)
- Intraflagellar transporter (161 kDa, Protein from Tetrahymena thermophila)
- Wd40 repeat protein (158 kDa, Protein from Tetrahymena thermophila)
- Ift-a_head-2 (Complex from Tetrahymena thermophila)
- Intraflagellar transport protein 122 homolog (143 kDa, Protein from Tetrahymena thermophila)
Tetrahymena telomerase with CST
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uy5
Q-score: 0.422
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Telomerase-associated protein of 75 kda (73 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 19 kda (19 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (9 kDa, DNA from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase-associated protein of 45 kda (43 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
Tetrahymena telomerase at 2.9 Angstrom resolution
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7uy6
Q-score: 0.506
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Zinc ion (65 Da, Ligand)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (19 kDa, DNA from Tetrahymena thermophila)
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
Tetrahymena CST with Polymerase alpha-Primase
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7uy7
Q-score: 0.293
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Telomerase-associated protein of 75 kda (73 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Telomerase-associated protein of 19 kda (19 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena dna polymerase alpha-primase (Complex from Tetrahymena thermophila)
- Tetrahymena cst (Complex from Tetrahymena thermophila)
- Dna polymerase (161 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (19 kDa, DNA from Tetrahymena thermophila)
- Telomerase-associated protein of 45 kda (43 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena cst-polaprim (Complex)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
Tetrahymena Polymerase alpha-Primase
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7uy8
Q-score: 0.229
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Zinc ion (65 Da, Ligand)
- Dna primase (47 kDa, Protein from Tetrahymena thermophila)
- Eukaryotic-type dna primase, large subunit (64 kDa, Protein from Tetrahymena thermophila)
- Dna polymerase (161 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena polaprim (Complex from Tetrahymena thermophila)
- Dna polymerase alpha subunit b (68 kDa, Protein from Tetrahymena thermophila)