Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ucj
Q-score: 0.507
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 12 (8 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 13 (12 kDa, Protein from Komagataella pastoris)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- Komagataella pastoris cytochrome c oxidase (11 subunits) in complex with human vmat2 (246 kDa, Complex from Homo sapiens)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 4 (16 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phoshocholine (734 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
Komagataella pastoris Cytochrome c oxidase (9 subunits) in complex with human VMAT2
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8uck
Q-score: 0.486
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 4 (12 kDa, Protein from Komagataella pastoris)
- Komagataella pastoris cytochrome c oxidase (9 subunits) in complex with human vmat2 (225 kDa, Complex from Homo sapiens)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
Komagataella pastoris Cytochrome c oxidase in complex with human VMAT2 and Tetrabenazine
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8ucl
Q-score: 0.511
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- (3s,5r,11bs)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2-one (317 Da, Ligand)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 4 (12 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase-vmat2-tetrabenazine particle (225 kDa, Complex from Homo sapiens)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
Komagataella pastoris Cytochrome c oxidase in complex with human VMAT2 and Reserpine
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8ucm
Q-score: 0.513
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Phosphatidylethanolamine (734 Da, Ligand)
- Reserpine (608 Da, Ligand)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 4 (12 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase-vmat2-reserpine particle (225 kDa, Complex from Homo sapiens)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
Komagataella pastoris Cytochrome c oxidase in complex with human VMAT2 and Histamine
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8ucn
Q-score: 0.486
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Heme-a (852 Da, Ligand)
- Komagataella pastoris cytochrome c oxidase in complex with human vmat2 and histamine (225 kDa, Complex from Homo sapiens)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
- Histamine (111 Da, Ligand)
- Cytochrome c oxidase subunit 4 (12 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8uco
Q-score: 0.484
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 4 (12 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- (2s)-1-phenylpropan-2-amine (135 Da, Ligand)
- Komagataella pastoris cytochrome c oxidase in complex with human vmat2 and amphetamin (225 kDa, Complex from Homo sapiens)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
Komagataella pastoris Cytochrome c oxidase in complex with human VMAT2 and Serotonin
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 8ucp
Q-score: 0.491
To Be Published
- Cytochrome c oxidase subunit 1 (58 kDa, Protein from Komagataella pastoris)
- Zinc ion (65 Da, Ligand)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome c oxidase subunit 8 (5 kDa, Protein from Komagataella pastoris)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Komagataella pastoris)
- Phosphatidylethanolamine (734 Da, Ligand)
- Cytochrome c oxidase-vmat2-serotonin complex (225 kDa, Complex from Homo sapiens)
- Cytochrome c oxidase subunit 7 (6 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 4 (12 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 6 (11 kDa, Protein from Komagataella pastoris)
- Synaptic vesicular amine transporter (55 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Cytochrome c oxidase subunit 3 (30 kDa, Protein from Komagataella pastoris)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 5 (14 kDa, Protein from Komagataella pastoris)
- Cytochrome c oxidase subunit 9 (6 kDa, Protein from Komagataella pastoris)
Human collagen prolyl processing enzyme complex, P3H1/CRTAP heterodimer
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 8k0e
Q-score: 0.407
Li W, Peng J, Yao D, Rao B, Xia Y, Wang Q, Li S, Cao M, Shen Y, Ma P, Liao R, Qin A, Zhao J, Cao Y
Nat Commun (2024) 15 pp. 7844-7844 [ DOI: doi:10.1038/s41467-024-52321-6 Pubmed: 39245686 ]
- Cartilage-associated protein (50 kDa, Protein from Homo sapiens)
- Prolyl 3-hydroxylase 1 (83 kDa, Protein from Homo sapiens)
- A protein modification binary complex (Complex from Homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, in its apo state
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8k0f
Q-score: 0.512
Li W, Peng J, Yao D, Rao B, Xia Y, Wang Q, Li S, Cao M, Shen Y, Ma P, Liao R, Qin A, Zhao J, Cao Y
Nat Commun (2024) 15 pp. 7844-7844 [ DOI: doi:10.1038/s41467-024-52321-6 Pubmed: 39245686 ]
- Peptidyl-prolyl cis-trans isomerase b (28 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- A protein modification ternary complex (Complex from Homo sapiens)
- Cartilage-associated protein (50 kDa, Protein from Homo sapiens)
- Prolyl 3-hydroxylase 1 (83 kDa, Protein from Homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8k0i
Q-score: 0.435
Li W, Peng J, Yao D, Rao B, Xia Y, Wang Q, Li S, Cao M, Shen Y, Ma P, Liao R, Qin A, Zhao J, Cao Y
Nat Commun (2024) 15 pp. 7844-7844 [ DOI: doi:10.1038/s41467-024-52321-6 Pubmed: 39245686 ]
- Peptidyl-prolyl cis-trans isomerase b (28 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Prolyl 3-hydroxylase 1 (83 kDa, Protein from Homo sapiens)
- A protein modification hexamer complex (Complex from Homo sapiens)
- Cartilage-associated protein (50 kDa, Protein from Homo sapiens)