P301L tau filaments from human brain
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
P301T type I tau filaments from human brain
Resolution: 2.26 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gg1
Q-score: 0.69
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
P301T type II tau filaments from human brain
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
PHF type tau filament from V337M mutant
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eo7
Q-score: 0.568
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
- Tau filament v337m (Complex from Homo sapiens)
- Isoform tau-f of microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
PHF type tau filament from V337M mutant
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eo9
Q-score: 0.486
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
PHF type tau filament from V337M mutant
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eoe
Q-score: 0.641
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
PHF type tau filament from R406W mutant
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eog
Q-score: 0.573
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Phf tau filament from mutant r406w (Complex from Homo sapiens)
PHF type tau filament from in vitro V337M mutant
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eoh
Q-score: 0.572
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
Resolution: 2.61 Å
EM Method: Helical reconstruction
Fitted PDBs: 8p34
Q-score: 0.647
Schweighauser M, Garringer HJ, Klingstedt T, Nilsson KPR, Masuda-Suzukake M, Murrell JR, Risacher SL, Vidal R, Scheres SHW, Goedert M, Ghetti B, Newell KL
Acta Neuropathol (2023) 146 pp. 211-226 [ Pubmed: 37351604 DOI: doi:10.1007/s00401-023-02598-6 ]
CryoEM structure of the helical assembly of full length MxB
Resolution: 4.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 5uot
Q-score: 0.197
Alvarez FJD, He S, Perilla JR, Jang S, Schulten K, Engelman AN, Scheres SHW, Zhang P
Sci Adv (2017) 3 pp. e1701264-e1701264 [ DOI: doi:10.1126/sciadv.1701264 Pubmed: 28929138 ]
- Helical assembly of mbp fusion of mxb (125 kDa, Complex from Homo sapiens)
- Interferon-induced gtp-binding protein mx2 (70 kDa, Protein from Homo sapiens)