P301L tau filaments from human brain
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
P301T type I tau filaments from human brain
Resolution: 2.26 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gg1
Q-score: 0.69
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
P301T type II tau filaments from human brain
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
CTE typeI tau filament from Guam ALS/PDC
Resolution: 2.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ot6
Q-score: 0.709
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
CTE typeIII tau filament from Guam ALS/PDC
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ot9
Q-score: 0.551
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
CTE typeII tau filament from Guam ALS/PDC
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otc
Q-score: 0.481
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
TMEM106B Fold1-s filament from Guam ALS/PDC
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otd
Q-score: 0.61
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
TMEM106B Fold I-d filament from Guam ALS/PDC
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ote
Q-score: 0.474
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tmem106b fold1-d filaments from guam als/pdc (Complex from Homo sapiens)
Ab typeII filament from Guam ALS/PDC
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otf
Q-score: 0.564
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Amyloid-beta precursor protein (87 kDa, Protein from Homo sapiens)
- Ab typeii filaments from guam als/pdc (Complex from Homo sapiens)
CTE typeI tau filament from Kii ALS/PDC
Resolution: 2.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otg
Q-score: 0.681
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Typei tau filaments from kii als/pdc (Complex from Homo sapiens)