Structure of the semi-extended AlphaIIbBeta3 in complex with R21D10 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9axl
Q-score: 0.473
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- Calcium ion (40 Da, Ligand)
- Integrin beta-3 (87 kDa, Protein from Homo sapiens)
- Integrin alpha-iib (113 kDa, Protein from Homo sapiens)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- Magnesium ion (24 Da, Ligand)
- R21d10 fab light chain (23 kDa, Protein from Mus musculus)
- R21d10 fab heavy chain (24 kDa, Protein from Mus musculus)
- Water (18 Da, Ligand)
The map of the bent AlphaIIbBeta3 in complex with R21D10 Fab
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- Integrin alphaiib (Protein from Homo sapiens)
- Alphaiibbeta3 integrin (Complex from Homo sapiens)
- Integrin beta3 (Protein from Homo sapiens)
- R21d10 fab (Complex from Mus musculus)
- R211010 fab light chain (Protein from Mus musculus)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- R21d10 fab heavy chain (Protein from Mus musculus)
Structure of the plasma coagulation Factor XIII A2B2 heterotetrameric complex.
Singh S, Hagelueken G, Ugurlar D, Ramaraje Urs SU, Sharma A, Mahapatra M, Drepper F, Imhof D, Huesgen PF, Oldenburg J, Geyer M, Biswas A
Blood (2025) 145 pp. 438-449 [ DOI: doi:10.1182/blood.2024025369 Pubmed: 39447073 ]
- Factor xiii a2b2 heterotetramer (Complex from Homo sapiens)
- Coagulation factor xiii a chain (83 kDa, Protein from Homo sapiens)
- Coagulation factor xiii b chain (75 kDa, Protein from Homo sapiens)
High resolution structure of the coagulation Factor XIII A2B2 heterotetramer complex.
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 8cmu
Q-score: 0.601
Singh S, Hagelueken G, Ugurlar D, Ramaraje Urs SU, Sharma A, Mahapatra M, Drepper F, Imhof D, Huesgen PF, Oldenburg J, Geyer M, Biswas A
Blood (2025) 145 pp. 438-449 [ DOI: doi:10.1182/blood.2024025369 Pubmed: 39447073 ]
- Factor xiii a2b2 heterotetramer (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Coagulation factor xiii a chain (83 kDa, Protein from Homo sapiens)
- Coagulation factor xiii b chain (75 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8uf7
Q-score: 0.36
Kumar S, Summers B, Basore K, Pengo V, Flaumenhaft R, Pozzi N
Blood (2024) 143 pp. 2005-2011 [ DOI: doi:10.1182/blood.2023022942 Pubmed: 38437497 ]
- Pomab heavy chain (23 kDa, Protein from Mus musculus)
- Prothrombin (65 kDa, Protein from Homo sapiens)
- Complex of fab fragment of pomab with human prothrombin (120 kDa, Complex from Mus musculus)
- Pomab light chain (23 kDa, Protein from Mus musculus)
Structure of the C3bB proconvertase in complex with lufaxin and factor Xa
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8eok
Q-score: 0.415
Andersen JF, Lei H, Strayer EC, Kanai T, Pham V, Pan XZ, Alvarenga PH, Gerber GF, Asojo OA, Francischetti IMB, Brodsky RA, Valenzuela JG, Ribeiro JMC
Blood (2023) 141 pp. 3109-3121 [ Pubmed: 36947859 DOI: doi:10.1182/blood.2022019359 ]
- Factor x light chain (15 kDa, Protein from Homo sapiens)
- Complement c3b alpha' chain (104 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Activated factor xa heavy chain (28 kDa, Protein from Homo sapiens)
- Complement c3 beta chain (71 kDa, Protein from Homo sapiens)
- The c3 proconvertase from the alternative pathway of complement in complex with lufaxin, a complement/coagulation inhibitor and coagulation factor xa (348 kDa, Complex from Homo sapiens)
- Lufaxin (33 kDa, Protein from Lutzomyia longipalpis)
- Magnesium ion (24 Da, Ligand)
- Complement factor b (85 kDa, Protein from Homo sapiens)
Consensus refinement of the h12-LOX in a dimeric form
Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A
Blood (2023) 142 pp. 1233-1242 [ DOI: doi:10.1182/blood.2023020441 Pubmed: 37506345 ]
The local refinement map of a "closed" subunit of a 12-LOX dimer
Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A
Blood (2023) 142 pp. 1233-1242 [ DOI: doi:10.1182/blood.2023020441 Pubmed: 37506345 ]
The local refinement map of an "open" subunit of a 12-LOX dimer
Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A
Blood (2023) 142 pp. 1233-1242 [ DOI: doi:10.1182/blood.2023020441 Pubmed: 37506345 ]
The consensus map of a 12-LOX hexamer
Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A
Blood (2023) 142 pp. 1233-1242 [ DOI: doi:10.1182/blood.2023020441 Pubmed: 37506345 ]