Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ore
Q-score: 0.593
Tarutani A, Lovestam S, Zhang X, Kotecha A, Robinson AC, Mann DMA, Saito Y, Murayama S, Tomita T, Goedert M, Scheres SHW, Hasegawa M
FEBS Open Bio (2023) 13 pp. 1394-1404 [ DOI: doi:10.1002/2211-5463.13657 Pubmed: 37337995 ]
- Tau amyloid filaments (Cell from Homo sapiens)
- Microtubule-associated protein tau (39 kDa, Protein from Homo sapiens)
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8orf
Q-score: 0.601
Tarutani A, Lovestam S, Zhang X, Kotecha A, Robinson AC, Mann DMA, Saito Y, Murayama S, Tomita T, Goedert M, Scheres SHW, Hasegawa M
FEBS Open Bio (2023) 13 pp. 1394-1404 [ DOI: doi:10.1002/2211-5463.13657 Pubmed: 37337995 ]
- Microtubule-associated protein tau (43 kDa, Protein from Homo sapiens)
- Tau amyloid filaments (Cell from Homo sapiens)
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts (Type II)
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8org
Q-score: 0.606
Tarutani A, Lovestam S, Zhang X, Kotecha A, Robinson AC, Mann DMA, Saito Y, Murayama S, Tomita T, Goedert M, Scheres SHW, Hasegawa M
FEBS Open Bio (2023) 13 pp. 1394-1404 [ DOI: doi:10.1002/2211-5463.13657 Pubmed: 37337995 ]
- Microtubule-associated protein tau (43 kDa, Protein from Homo sapiens)
- Tau amyloid filaments (Cell from Homo sapiens)
Cryo-EM structure of the human RAD52 protein
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8h1p
Q-score: 0.463
Kinoshita C, Takizawa Y, Saotome M, Ogino S, Kurumizaka H, Kagawa W
FEBS Open Bio (2023) 13 pp. 408-418 [ DOI: doi:10.1002/2211-5463.13565 Pubmed: 36707939 ]
- Dna repair protein rad52 homolog (46 kDa, Protein from Homo sapiens)
- Rad52 (Cellular component from Homo sapiens)
Resolution: 3.47 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nca
Q-score: 0.559
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.43 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ncg
Q-score: 0.494
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.84 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nch
Q-score: 0.244
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.55 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nci
Q-score: 0.377
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 4.23 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ncj
Q-score: 0.176
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.18 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nck
Q-score: 0.498
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)