Low resolution cryo-EM structure of FHF bound to KIF1C stalk Hook3 binding domain
Abid Ali F, Zwetsloot AJ, Stone CE, Morgan TE, Wademan RF, Carter AP, Straube A
Nat Struct Mol Biol (2025) [ Pubmed: 39747486 DOI: doi:10.1038/s41594-024-01418-z ]
- Fhip1b (Protein from Homo sapiens)
- Hook3(451-718) (Protein from Homo sapiens)
- Fts (Protein from Homo sapiens)
- Kif1c(674-922) (Protein from Homo sapiens)
- The fts-hook3(451-718)-fhip1b complex bound to kif1c hook3 binding domain (kif1c 647-922) (430 kDa, Complex from Homo sapiens)
Cryo-EM structure of TRNM-f*01 Fab in complex with HIV-1 Env trimer ConC SOSIP
Resolution: 4.03 Å
EM Method: Single-particle
Fitted PDBs: 8to9
Q-score: 0.305
Wang H, Cheng C, Dal Santo JL, Shen CH, Bylund T, Henry AR, Howe CA, Hwang J, Morano NC, Morris DJ, Pletnev S, Roark RS, Zhou T, Hansen BT, Hoyt FH, Johnston TS, Wang S, Zhang B, Ambrozak DR, Becker JE, Bender MF, Changela A, Chaudhary R, Corcoran M, Corrigan AR, Foulds KE, Guo Y, Lee M, Li Y, Lin BC, Liu T, Louder MK, Mandolesi M, Mason RD, McKee K, Nair V, O'Dell S, Olia AS, Ou L, Pegu A, Raju N, Rawi R, Roberts-Torres J, Sarfo EK, Sastry M, Schaub AJ, Schmidt SD, Schramm CA, Schwartz CL, Smith SC, Stephens T, Stuckey J, Teng IT, Todd JP, Tsybovsky Y, Van Wazer DJ, Wang S, Doria-Rose NA, Fischer ER, Georgiev IS, Karlsson Hedestam GB, Sheng Z, Woodward RA, Douek DC, Koup RA, Pierson TC, Shapiro L, Shaw GM, Mascola JR, Kwong PD
Cell (2024) 187 pp. 7214-7231.e23 [ Pubmed: 39471811 DOI: doi:10.1016/j.cell.2024.10.003 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Trnm-f*01 light chain (11 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp120 (52 kDa, Protein from Homo sapiens)
- Trnm-f*01 heavy chain (13 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (17 kDa, Protein from Homo sapiens)
- Trnm-f*01 fab in complex with hiv-1 env trimer conc sosip (Complex from Macaca mulatta)
Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 9cmh
Q-score: 0.251
Rathnayake SS, Erramilli SK, Kossiakoff AA, Vecchio AJ
Structure (2024) 32 pp. 1936- [ DOI: doi:10.1016/j.str.2024.09.015 Pubmed: 39383874 ]
- Heat-labile enterotoxin b chain (33 kDa, Protein from Clostridium perfringens)
- Claudin-4 (22 kDa, Protein from Homo sapiens)
- Human claudin-4 complex with clostridium perfringens enterotoxin (55 kDa, Complex from other entries)
Engaged conformation of the human mitochondrial DNA polymerase gamma bound to DNA
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8v54
Q-score: 0.348
Riccio AA, Brannon AJ, Krahn JM, Bouvette J, Williams JG, Borgnia MJ, Copeland WC
Nucleic Acids Res (2024) 52 pp. 7863-7875 [ Pubmed: 38932681 DOI: doi:10.1093/nar/gkae539 ]
- Complex of the human mitochondrial dna polymerase gamma (polg/polg2 heterotrimer) bound to a dna fork in an engaged conformation (220 kDa, Complex from Homo sapiens)
- Dna polymerase subunit gamma-2, mitochondrial (53 kDa, Protein from Homo sapiens)
- Dna (44-mer) (13 kDa, DNA from Homo sapiens)
- Dna (25-mer) (7 kDa, DNA from Homo sapiens)
- Dna polymerase subunit gamma-1 (138 kDa, Protein from Homo sapiens)
Human mitochondrial DNA polymerase gamma bound to a replication fork in an open conformation
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8v55
Q-score: 0.232
Riccio AA, Brannon AJ, Krahn JM, Bouvette J, Williams JG, Borgnia MJ, Copeland WC
Nucleic Acids Res (2024) 52 pp. 7863-7875 [ Pubmed: 38932681 DOI: doi:10.1093/nar/gkae539 ]
- Dna polymerase subunit gamma-2, mitochondrial (53 kDa, Protein from Homo sapiens)
- Human mitochondrial dna polymerase gamma bound to dna in an open conformation (220 kDa, Complex from Homo sapiens)
- Dna template chain (13 kDa, DNA from Homo sapiens)
- Dna primer chain (7 kDa, DNA from Homo sapiens)
- Dna polymerase subunit gamma-1 (138 kDa, Protein from Homo sapiens)
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 9bei
Q-score: 0.276
Goverde CA, Pacesa M, Goldbach N, Dornfeld LJ, Balbi PEM, Georgeon S, Rosset S, Kapoor S, Choudhury J, Dauparas J, Schellhaas C, Kozlov S, Baker D, Ovchinnikov S, Vecchio AJ, Correia BE
Nature (2024) 631 pp. 449-458 [ Pubmed: 38898281 DOI: doi:10.1038/s41586-024-07601-y ]
- Cop-2 fab heavy chain (25 kDa, Protein from Escherichia coli)
- Anti-fab nanobody (13 kDa, Protein from Escherichia coli)
- Claudin-4 (22 kDa, Protein from Homo sapiens)
- Synthetic human claudin-4 complex with clostridium perfringens enterotoxin c-terminal domain, sfab cop-2, and nanobody against cop-2 (103 kDa, Complex from Homo sapiens)
- Heat-labile enterotoxin b chain (14 kDa, Protein from Clostridium perfringens)
- Cop-2 fab light chain (23 kDa, Protein from Escherichia coli)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgg
Q-score: 0.26
Mukhopadhyay AG, Toropova K, Daly L, Wells JN, Vuolo L, Mladenov M, Seda M, Jenkins D, Stephens DJ, Roberts AJ
EMBO J (2024) 43 pp. 1257-1272 [ Pubmed: 38454149 DOI: doi:10.1038/s44318-024-00060-1 ]
- Cytoplasmic dynein 2 intermediate chain 2 (60 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein 2 intermediate chain 1 (122 kDa, Protein from Homo sapiens)
- Methylated-dna--protein-cysteine methyltransferase,cytoplasmic dynein 2 heavy chain 1 (515 kDa, Protein from Homo sapiens)
- Dynein light chain 1, cytoplasmic (10 kDa, Protein from Homo sapiens)
- Dynein-2 complex (Complex from Homo sapiens)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from Homo sapiens)
GMPCPP-microtubule decorated with Abl2-557-1090
Duan D, Lyu W, Chai P, Ma S, Wu K, Wu C, Xiong Y, Sestan N, Zhang K, Koleske AJ
Curr Biol (2023) 33 pp. 4582-4598.e10 [ DOI: doi:10.1016/j.cub.2023.09.018 Pubmed: 37858340 ]
- Abl2 c-terminals (557-1090) (Protein from Homo sapiens)
- Abl2-557-1090 (Complex from Homo sapiens)
- Gmpcpp-microtubule (Complex from Sus scrofa)
- Beta-tubulin (Protein from Sus scrofa)
- Alpha-tubulin (Protein from Sus scrofa)
- Gmpcpp-microtubules decorated with abl2-557-1090. (500 kDa, Complex)
Protofilament reconstruction of microtubule decorated with Abl2-557-1090, Class 1
Protofilament reconstruction of microtubule decorated with Abl2-557-1090, Class 2