WEE1 bound to CRBN-DDB1 via compound 10 (CRBN open conformation)
Razumkov H, Jiang Z, Baek K, You I, Geng Q, Donovan KA, Tang MT, Metivier RJ, Mageed N, Seo P, Li Z, Byun WS, Hinshaw SM, Sarott RC, Fischer ES, Gray NS
J Am Chem Soc (2024) 146 pp. 31433-31443 [ DOI: doi:10.1021/jacs.4c06127 Pubmed: 39499896 ]
Structural Basis of Human NOX5 Activation
To Be Published
- Nadph oxidase 5 (Complex from Homo sapiens)
- Nadph oxidase 5 (nox5) (Protein from Homo sapiens)
Structural Basis of Human NOX5 Activation
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 8u7y
Q-score: 0.327
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Dodecane (170 Da, Ligand)
Cryo-EM structure of ATP13A2 in the putative of E2 state
Resolution: 4.87 Å
EM Method: Single-particle
Fitted PDBs: 8ier
Q-score: 0.162
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ Pubmed: 37031211 DOI: doi:10.1038/s41467-023-37741-0 ]
- Spermine (202 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the putative of e2 state (Complex from Homo sapiens)
Human TRPV3 pentamer structure
Resolution: 4.38 Å
EM Method: Single-particle
Fitted PDBs: 8gkg
Q-score: 0.304
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S
Nature (2023) 621 pp. 206-214 [ DOI: doi:10.1038/s41586-023-06470-1 Pubmed: 37648856 ]
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Human IFT-A complex structures provide molecular insights into ciliary transport
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8fh3
Q-score: 0.248
Jiang M, Palicharla VR, Miller D, Hwang SH, Zhu H, Hixson P, Mukhopadhyay S, Sun J
Cell Res (2023) 33 pp. 288-298 [ DOI: doi:10.1038/s41422-023-00778-3 Pubmed: 36775821 ]
- Zinc ion (65 Da, Ligand)
- Wd repeat-containing protein 19 (151 kDa, Protein from Homo sapiens)
- Ift-a_tulp3 (Complex from Homo sapiens)
- Intraflagellar transport complex a (ift-a) (Complex from Homo sapiens)
- Intraflagellar transport protein 122 homolog (141 kDa, Protein from Homo sapiens)
- Intraflagellar transport protein 140 homolog (165 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 35 (133 kDa, Protein from Homo sapiens)
- Tubby-related protein 3 (49 kDa, Protein from Homo sapiens)
SARS-CoV-2 RBD in complex with 1F Fab
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7y7k
Q-score: 0.241
Zhao S, Liu F, Qiu S, Lan Q, Wu Y, Xu W, Ke J, Yang J, Liu X, Wang K, Guo H, Xia S, Zhang F, Wang J, Hu X, Lu L, Jiang S, Zhao S, Liu L, Xie Y, Yang X, Wang H, Zhong G
Protein Cell (2023) 14 pp. 74-78 [ Pubmed: 36726762 DOI: doi:10.1093/procel/pwac042 ]
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 rbd complex with 1f fab (Complex)
- 1f fab (Complex from Homo sapiens)
- 1f vh (14 kDa, Protein from Homo sapiens)
- Spike protein s1 (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 1f vl (11 kDa, Protein from Homo sapiens)
Human L-TGF-beta1 in complex with the anchor protein LRRC33
Resolution: 4.01 Å
EM Method: Single-particle
Fitted PDBs: 7y1r
Q-score: 0.187
Duan Z, Lin X, Wang L, Zhen Q, Jiang Y, Chen C, Yang J, Lee CH, Qin Y, Li Y, Zhao B, Wang J, Zhang Z
Nat Commun (2022) 13 pp. 4988-4988 [ Pubmed: 36008481 DOI: doi:10.1038/s41467-022-32655-9 ]
- Transforming growth factor beta activator lrrc33 (72 kDa, Protein from Homo sapiens)
- L-tgf-beta1 in complex with its anchor protein lrrc33 (150 kDa, Complex from Homo sapiens)
- Transforming growth factor beta-1 proprotein (43 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Jiang Q, Foglizzo M, Morozov YI, Yang X, Datta A, Tian L, Thada V, Li W, Zeqiraj E, Greenberg RA
J Cell Biol (2022) 221 [ Pubmed: 35938958 DOI: doi:10.1083/jcb.202111050 ]