PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
Resolution: 4.19 Å
EM Method: Single-particle
Fitted PDBs: 8e97
Q-score: 0.336
Chou TH, Kang H, Simorowski N, Traynelis SF, Furukawa H
Mol Cell (2022) 82 pp. 4548- [ DOI: doi:10.1016/j.molcel.2022.10.008 Pubmed: 36309015 ]
- Glutamate receptor ionotropic, nmda 2c (96 kDa, Protein from Homo sapiens)
- Hetero-tetrameric glun1a-glun2c nmda receptors (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4
Resolution: 4.24 Å
EM Method: Single-particle
Fitted PDBs: 8e99
Q-score: 0.363
Chou TH, Kang H, Simorowski N, Traynelis SF, Furukawa H
Mol Cell (2022) 82 pp. 4548- [ DOI: doi:10.1016/j.molcel.2022.10.008 Pubmed: 36309015 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (97 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2c (96 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Hetero-tetrameric glun1a-glun2c nmda receptors (Complex from Homo sapiens)
- Nanobody 4 (16 kDa, Protein from Lama glama)
Full-length human E-cadherin bound to 19A11 activating Fab
To Be Published
- Complex of human e-cadherin monomer with activating fab 19a11 (130 kDa, Complex)
- Activating antibody fragment 19a11 heavy chain (Protein from Mus musculus)
- Activating antibody fragment 19a11 light chain (Protein from Mus musculus)
- Full length e-cadherin with twin-strep tag (80 kDa, Complex from Homo sapiens)
- Activating antibody fragment 19a11 (50 kDa, Complex from Mus musculus)
- E-cadherin (cdh1) with c-terminal twin-strep tag (Protein from Homo sapiens)
Full-length human E-cadherin bound to neutral Fab 46H7
To Be Published
- Complex of human e-cadherin monomer with neutral fab 46h7 (130 kDa, Complex)
- Neutral antibody fragment 46h7 fab (50 kDa, Complex from Mus musculus)
- Neutral antibody fragment 46h7 heavy chain (Protein from Mus musculus)
- Full length e-cadherin with twin-strep tag (80 kDa, Complex from Homo sapiens)
- Neutral antibody fragment 46h7 light chain (Protein from Mus musculus)
- E-cadherin (cdh1) with c-terminal twin-strep tag (Protein from Homo sapiens)
Cryo-EM structure of human TMEM120A in the CoASH-free state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7f3u
Q-score: 0.335
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ DOI: doi:10.7554/eLife.71474 Pubmed: 34409941 ]
- Transmembrane protein 120a (Cell from Homo sapiens)
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)
Human AAA+ ATPase VCP mutant - T76E, AMP-PNP bound form, Conformation I
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7bpb
Q-score: 0.366
Zhu K, Cai Y, Si X, Ye Z, Gao Y, Liu C, Wang R, Ma Z, Zhu H, Zhang L, Li S, Zhang H, Yue J
Cell Death Differ. (2022) [ DOI: doi:10.1038/s41418-022-01000-4 Pubmed: 35430615 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transitional endoplasmic reticulum atpase, vcp. (97 MDa, Complex from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
Noncatalytic conformation Dot1 bound to the unacetylated H4 nucleosome
Valencia-Sanchez MI, De Ioannes P, Wang M, Truong DM, Lee R, Armache JP, Boeke JD, Armache KJ
Science (2021) 371 [ DOI: doi:10.1126/science.abc6663 Pubmed: 33479126 ]
- Histone h3.2 (Protein from Xenopus lenduensis)
- Histone h2a type 1 (Protein from Xenopus laevis)
- Histone h2b 1.1 (Protein from Xenopus laevis)
- Dna (146-mer) (DNA from synthetic construct)
- Polyubiquitin-b (Protein from Homo sapiens)
- Noncatalytic conformation dot1 bound to the unacetylated h4 nucleosome (Complex from Saccharomyces cerevisiae)
- Histone h4 (Protein from Xenopus laevis)
- Histones (Complex from Xenopus laevis)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (Complex from Saccharomyces cerevisiae)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (Protein from Saccharomyces cerevisiae)
- Dna (146-mer) (Complex from Synthetic)
- Polyubiquitin-b (Complex from Homo sap)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Sars-cov-2 receptor binding domain in complex with the fab fragment of neutralizing antibody 46 (Complex)
- Fab 46 heavy chain (Protein from Homo sapiens)
- Sars-cov-2 receptor binding domain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Receptor binding domain of sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab fragment of neutralizing antibody 46 (Complex from Homo sapiens)
- Fab 46 light chain (Protein from Homo sapiens)