PI3KC3-C1 in complex with RAB1A. VPS34 kinase domain active conformation
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 9mhh
Q-score: 0.373
Cook ASI, Chen M, Ngyuen TN, Claveras-Cabezudo A, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH
To Be Published
- Phosphoinositide 3-kinase regulatory subunit 4 (158 kDa, Protein from Homo sapiens)
- Ras-related protein rab-1a (25 kDa, Protein from Homo sapiens)
- Beclin 1-associated autophagy-related key regulator (55 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphatidylinositol-3 kinase class iii complex i bound to rab1a (384 kDa, Complex from Homo sapiens)
- Beclin-1 (51 kDa, Protein from Homo sapiens)
- Phosphatidylinositol 3-kinase catalytic subunit type 3 (101 kDa, Protein from Homo sapiens)
3D Reconstruction of TH-DNAJC12 WT Complex
Tai MDS, Ochoa L, Flydal MI, Velasco L, Muntaner J, Santiago C, Jung-KC K, Stove SI, Moro F, Kallio JP, Muga A, Valpuesta JM, Cuellar J, Martinez A
To Be Published
- Tyrosine hydroxylate (Protein from Homo sapiens)
- Dnajc12 (Protein from Homo sapiens)
- Th-dnajc12 complex (265 kDa, Complex from Homo sapiens)
Structure of the Ebola virus nucleocapsid subunit
Fujita-Fujiharu Y, Hu S, Hirabayashi A, Takamatsu Y, Ng Y, Houri K, Muramoto Y, Nakano M, Sugita Y, Noda T
To Be Published
- Rna (12-mer) (3 kDa, RNA from Homo sapiens)
- Nucleoprotein (83 kDa, Protein from Zaire ebolavirus)
- Membrane-associated protein vp24 (28 kDa, Protein from Zaire ebolavirus)
- Zaire ebolavirus (Virus from Zaire ebolavirus)
Human ACKR3 phosphorylated by GRK2 in complex with Arrestin3 reconstructed without receptor/micelle
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8tin
Q-score: 0.326
To Be Published
- Fab7 heavy chain (25 kDa, Protein from synthetic construct)
- Fab7 light chain (23 kDa, Protein from synthetic construct)
- Beta-arrestin-2 (44 kDa, Protein from Bos taurus)
- Human ackr3 phosphorylated by grk2 in complex with arrestin3 reconstructed without receptor/micelle (Complex from Bos taurus)
- Atypical chemokine receptor 3 (45 kDa, Protein from Homo sapiens)
Bangaru S, Jackson AM, Copps J, Fernandez-Quintero ML, Torres JL, Richey ST, Nogal B, Sewall LM, de la Pena AT, Rehman A, Guebre-Xabier M, Girard B, Das R, Corbett-Helaire KS, Seder RA, Graham BS, Edwards DK, Patel N, Smith G, Ward AB
bioRxiv (2024) [ DOI: doi:10.1101/2024.12.11.628030 Pubmed: 39713412 ]
DNA Polymerase Beta bound to a nucleosome containing a 1-nt gap at SHL-3.5
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 9dwk
Q-score: 0.297
Weaver TM, Ryan BJ, Freudenthal BD
To Be Published
- Histone h2a type 1 (13 kDa, Protein from Homo sapiens)
- Dna polymerase beta bound to a nucleosome containing a 1-nt gap at shl-3.5 (Complex from Homo sapiens)
- 601 k strand (damaged strand 2) (12 kDa, DNA from synthetic construct)
- Histone h2b type 1-c/e/f/g/i (13 kDa, Protein from Homo sapiens)
- 601 i strand (damaged strand 1) (32 kDa, DNA from synthetic construct)
- 601 j strand (non-damaged strand) (45 kDa, DNA from synthetic construct)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)
- Dna polymerase beta (38 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
DNA polymerase Beta bound to a nucleosome containing a 1-nt gap at SHL-5.5
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 9dwm
Q-score: 0.31
Ryan BJ, Weaver TM, Freudenthal BD
To Be Published
- Histone h2a type 1 (13 kDa, Protein from Homo sapiens)
- Histone h2b type 1-c/e/f/g/i (13 kDa, Protein from Homo sapiens)
- 601 j strand (non-damaged strand) (45 kDa, DNA from synthetic construct)
- Dna polymerase beta (38 kDa, Protein from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)
- 601 k strand (damaged strand 2) (5 kDa, DNA from synthetic construct)
- Nucleosome containing a 1-nt gap at shl-5.5 (Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- 601 i strand (damaged strand 1) (38 kDa, DNA from synthetic construct)
RNA Polymerase III Class III Open Mini Pre-Initiation complex 2 (OC2-mini)
Resolution: 4.14 Å
EM Method: Single-particle
Fitted PDBs: 9fss
Q-score: 0.264
Shah SZ, Perry TN, Graziadei A, Cecatiello V, Kaliyappan T, Misiaszek AD, Muller CW, Ramsay EP, Vannini A
Nat Commun (2025) 16 pp. 141-141 [ Pubmed: 39747245 DOI: doi:10.1038/s41467-024-55553-8 ]
- U6_2_template (30 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Tfiiib (Complex from Homo sapiens)
- Rna polymerase iii (Complex from Homo sapiens)
- Snapc (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Transcription factor tfiiib component b'' homolog (55 kDa, Protein from Homo sapiens)
- U6_2_non template (30 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Rna polymerase iii class iii open mini pre-initiation complex 2 (Complex)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna (Complex from Homo sapiens)
- Snrna-activating protein complex subunit 4 (165 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Tata-box-binding protein (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
Human mitochondrial RNase Z complex with tRNA-Gln precursor - Focused map around ELAC2
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]