Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D
Cell (2017) 171 pp. 229-241.e15 [ Pubmed: 28938115 DOI: doi:10.1016/j.cell.2017.09.002 ]
IMPDH Filament in the GTP-bound collapsed conformation
Anthony SA, Burrell AL, Johnson MC, Duong-Ly KC, Kuo YM, Simonet JC, Michener P, Andrews A, Kollman JM, Peterson JR
Mol Biol Cell (2017) [ DOI: doi:10.1091/mbc.E17-04-0263 Pubmed: 28794265 ]
- Impdh filament, collapsed conformation (385 MDa, Complex from Homo sapiens)
IMPDH Filament in the expanded conformation
Anthony SA, Burrell AL, Johnson MC, Duong-Ly KC, Kuo YM, Simonet JC, Michener P, Andrews A, Kollman JM, Peterson JR
Mol Biol Cell (2017) [ DOI: doi:10.1091/mbc.E17-04-0263 Pubmed: 28794265 ]
- Impdh filament, expanded conformation (385 MDa, Complex from Homo sapiens)
Cryo-EM reconstruction of B41 SOSIP.664 in complex with fragment antigen binding of PGV04
Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB
Nature (2017) 547 pp. 360-363 [ DOI: doi:10.1038/nature23010 Pubmed: 28700571 ]
- Pgv04 fab heavy chain (Protein from Homo sapiens)
- Hiv-1 env b41 sosip.664 in complex with pgv04 fragment antigen binding (570 kDa, Complex)
- Hiv-1 env b41 sosip.664 gp120 (Protein from Human immunodeficiency virus 1)
- Pgv04 fragment antigen (Complex from Homo sapiens)
- Pgv04 fab light chain (Protein from Homo sapiens)
- Hiv-1 env b41 sosip.664 gp41 (Protein from Human immunodeficiency virus 1)
- Hiv-1 env b41 sosip.664 (Complex from Human immunodeficiency virus 1)
Human RAD51 presynaptic complex
Resolution: 4.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 5h1b
Q-score: 0.372
Xu J, Zhao L, Xu Y, Zhao W, Sung P, Wang HW
Nat Struct Mol Biol (2017) 24 pp. 40-46 [ Pubmed: 27941862 DOI: doi:10.1038/nsmb.3336 ]
- Human rad51 and ssdna formed presynaptic complex (23 MDa, Complex from human)
- Ssdna (Complex)
- Magnesium ion (24 Da, Ligand)
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*t)-3') (2 kDa, DNA from Homo sapiens)
- Dna repair protein rad51 homolog 1 (37 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Human rad51 (Complex)
Structural basis for dynamic regulation of the human 26S proteasome
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 5t0j
Q-score: 0.116
Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y
PNAS (2016) 113 pp. 12991-12996 [ Pubmed: 27791164 DOI: doi:10.1073/pnas.1614614113 ]
- 26s proteasome holoenzyme (2 MDa, Complex from Homo sapiens)