Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8cyi
Q-score: 0.451
Zhou W, Yadav GP, Yang X, Qin F, Li C, Jiang QX
Commun Biol (2022) 5 pp. 1054-1054 [ Pubmed: 36192627 DOI: doi:10.1038/s42003-022-03991-9 ]
- Protein arginine n-methyltransferase 5 (72 kDa, Protein from Homo sapiens)
- N-[(2-aminoquinolin-7-yl)methyl]-9-(2-hydroxyethyl)-2,3,4,9-tetrahydro-1h-carbazole-6-carboxamide (414 Da, Ligand)
- 5'-deoxy-5'-methylthioadenosine (297 Da, Ligand)
- Complex of prmt5 and mep50 in the presence of mta and a novel inhibitor (11-2f) (440 kDa, Complex from Homo sapiens)
- Methylosome protein 50 (33 kDa, Protein from Homo sapiens)
Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7bpa
Q-score: 0.512
Zhu K, Cai Y, Si X, Ye Z, Gao Y, Liu C, Wang R, Ma Z, Zhu H, Zhang L, Li S, Zhang H, Yue J
Cell Death Differ. (2022) [ Pubmed: 35430615 DOI: doi:10.1038/s41418-022-01000-4 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Transitional endoplasmic reticulum atpase, vcp. (97 MDa, Complex from Homo sapiens)
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 7dnh
Q-score: 0.403
He M, Chi X, Zha Z, Li Y, Chen J, Huang Y, Huang S, Yu M, Wang Z, Song S, Liu X, Wei S, Li Z, Li T, Wang Y, Yu H, Zhao Q, Zhang J, Zheng Q, Gu Y, Li S, Xia N
J Virol (2021) 95 [ Pubmed: 33472937 DOI: doi:10.1128/JVI.01587-20 ]
- Major capsid protein l1 (59 kDa, Protein from Human papillomavirus type 58)
- The light chain of 2h3 fab fragment (23 kDa, Protein from Mus musculus)
- Human papillomavirus type 58 (Complex from Mus musculus)
- Mus musculus (Complex)
- Human papillomavirus type 58 in complexed with the fab fragment of 2h3 (Complex from Human papillomavirus type 58)
- The heavy chain of 2h3 fab fragment (23 kDa, Protein from Mus musculus)
CryoEM structure of the LbCas12a-crRNA-AcrVA4 complex
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 6nma
Q-score: 0.489
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD, Chang L
Cell Host Microbe (2019) 25 pp. 815- [ Pubmed: 31155345 DOI: doi:10.1016/j.chom.2019.05.004 ]
- Acrva1 (27 kDa, Protein from Moraxella bovoculi)
- Magnesium ion (24 Da, Ligand)
- Rna (12 kDa, RNA from Lachnospiraceae bacterium ND2006)
- Protein complex 4 (Complex from Lachnospiraceae bacterium ND2006)
- Cpf1 (143 kDa, Protein from Lachnospiraceae bacterium ND2006)
cryo-EM Structure of the LbCas12a-crRNA-AcrVA1 complex
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 6nmd
Q-score: 0.185
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD, Chang L
Cell Host Microbe (2019) 25 pp. 815- [ Pubmed: 31155345 DOI: doi:10.1016/j.chom.2019.05.004 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Cpf1 (143 kDa, Protein from Lachnospiraceae bacterium ND2006)
- Protein complex 2 (Complex from Lachnospiraceae bacterium ND2006)
- Acrva1 (20 kDa, Protein from Moraxella bovoculi)
- Crrna (12 kDa, RNA from Lachnospiraceae bacterium ND2006)
CryoEM structure of the LbCas12a-crRNA-AcrVA4 dimer
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 6nm9
Q-score: 0.411
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD, Chang L
Cell Host Microbe (2019) 25 pp. 815- [ Pubmed: 31155345 DOI: doi:10.1016/j.chom.2019.05.004 ]
- Rna (25-mer) (12 kDa, RNA from Lachnospiraceae bacterium ND2006)
- Magnesium ion (24 Da, Ligand)
- Cpf1 (143 kDa, Protein from Lachnospiraceae bacterium ND2006)
- Acrva4 (27 kDa, Protein from Moraxella bovoculi)
- Protein complex 5 (Complex from Lachnospiraceae bacterium ND2006)
In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (DLP)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6oj4
Q-score: 0.508
Jenni S, Salgado EN, Herrmann T, Li Z, Grant T, Grigorieff N, Trapani S, Estrozi LF, Harrison SC
J Mol Biol (2019) 431 pp. 3124-3138 [ Pubmed: 31233764 DOI: doi:10.1016/j.jmb.2019.06.016 ]
- Inner capsid protein vp2 (103 kDa, Protein from Rotavirus A (strain RVA/Monkey/United States/RRV/1975/G3P5B[3]))
- Rotavirus a (strain rva/monkey/united states/rrv/1975/g3p5b[3]) (Virus from Rotavirus A (strain RVA/Monkey/United States/RRV/1975/G3P5B[3]))
- Rna-directed rna polymerase (125 kDa, Protein from Rotavirus A (strain RVA/Monkey/United States/RRV/1975/G3P5B[3]))
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6o1v
Q-score: 0.482
Liu F, Zhang Z, Levit A, Levring J, Touhara KK, Shoichet BK, Chen J
Science (2019) 364 pp. 1184-1188 [ DOI: doi:10.1126/science.aaw7611 Pubmed: 31221859 ]
- Cystic fibrosis transmembrane conductance regulator (169 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Unknown peptide (1 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Complex of human cystic fibrosis transmembrane conductance regulator (cftr) and glpg1837 (168 kDa, Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- N-(3-carbamoyl-5,5,7,7-tetramethyl-4,7-dihydro-5h-thieno[2,3-c]pyran-2-yl)-1h-pyrazole-3-carboxamide (348 Da, Ligand)
Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6o2p
Q-score: 0.46
Liu F, Zhang Z, Levit A, Levring J, Touhara KK, Shoichet BK, Chen J
Science (2019) 364 pp. 1184-1188 [ DOI: doi:10.1126/science.aaw7611 Pubmed: 31221859 ]
- Cystic fibrosis transmembrane conductance regulator (169 kDa, Protein from Homo sapiens)
- N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (392 Da, Ligand)
- Unknown peptide (1 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Complex of ivacaftor and cystic fibrosis transmembrane conductance regulator (cftr) (168 kDa, Complex from Homo sapiens)
- Digitonin (1 kDa, Ligand)