Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8vgi
Q-score: 0.49
Kung JE, Johnson MC, Jao CC, Arthur CP, Tegunov D, Rohou A, Sudhamsu J
bioRxiv (2024) [ DOI: doi:10.1101/2024.05.10.593593 Pubmed: 38798381 ]
- Fab e104.v1.2ds light chain (23 kDa, Protein from Homo sapiens)
- Anti-tryptase fab e104.v1.2ds (Complex from Homo sapiens)
- Tryptase tetramer (Complex from Homo sapiens)
- Tryptase alpha/beta-1 (29 kDa, Protein from Homo sapiens)
- Fab e104.v1.2ds heavy chain (25 kDa, Protein from Homo sapiens)
- Tryptase tetramer in complex with fab e104.v1.2ds (Complex)
- Water (18 Da, Ligand)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8vgj
Q-score: 0.512
Kung JE, Johnson MC, Jao CC, Arthur CP, Tegunov D, Rohou A, Sudhamsu J
bioRxiv (2024) [ DOI: doi:10.1101/2024.05.10.593593 Pubmed: 38798381 ]
- Anti-tryptase fab e104.v1.4ds (Complex from Homo sapiens)
- Fab e104.v1.4ds light chain (23 kDa, Protein from Homo sapiens)
- Tryptase tetramer (Complex from Homo sapiens)
- Tryptase alpha/beta-1 (29 kDa, Protein from Homo sapiens)
- Tryptase tetramer in complex with fab e104.v1.4ds (Complex)
- Fab e104.v1.4ds heavy chain (25 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8vgk
Q-score: 0.505
Kung JE, Johnson MC, Jao CC, Arthur CP, Tegunov D, Rohou A, Sudhamsu J
bioRxiv (2024) [ DOI: doi:10.1101/2024.05.10.593593 Pubmed: 38798381 ]
- Tryptase tetramer (Complex from Homo sapiens)
- Tryptase alpha/beta-1 (27 kDa, Protein from Homo sapiens)
- Fab e104.v1.6ds light chain (23 kDa, Protein from Homo sapiens)
- Anti-tryptase fab e104.v1.6ds (Complex from Homo sapiens)
- Fab e104.v1.6ds light chain (25 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Tryptase tetramer in complex with fab e104.v1.6ds (Complex)
Human p97/VCP R155H mutant structure with a triazole inhibitor (NSC804515)
Nandi P, DeVore K, Wang F, Li S, Walker JD, Truong TT, LaPorte MG, Wipf P, Schlager H, McCleerey J, Paquette W, Columbres RCA, Gan T, Poh YP, Fromme P, Flint AJ, Wolf M, Huryn DM, Chou TF, Chiu PL
Commun Chem (2024) 7 pp. 177-177 [ DOI: doi:10.1038/s42004-024-01267-3 Pubmed: 39122922 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- N-[3-(2,5-difluoro-4-{[(4m)-5-(hexylsulfanyl)-4-(pyridin-3-yl)-4h-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl]propanamide (513 Da, Ligand)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
- P97/vcp aaa+ atpase r155h mutant/nsc804515 (536 kDa, Complex from Homo sapiens)
ATP-1 state of Bcs1 (C7 symmetrized)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8t5u
Q-score: 0.449
Zhan J, Zeher A, Huang R, Tang WK, Jenkins LM, Xia D
Nat Commun (2024) 15 pp. 4655-4655 [ DOI: doi:10.1038/s41467-024-49029-y Pubmed: 38821922 ]
- Heptameric bcs1 in uniform atp-bound state captured during active atpase cycle (340 kDa, Complex from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Mitochondrial chaperone bcs1 (48 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
ATP-1 state of Bcs1 (unsymmetrized)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 8ti0
Q-score: 0.312
Zhan J, Zeher A, Huang R, Tang WK, Jenkins LM, Xia D
Nat Commun (2024) 15 pp. 4655-4655 [ DOI: doi:10.1038/s41467-024-49029-y Pubmed: 38821922 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Mitochondrial chaperone bcs1 (48 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Heptameric bcs1 in uniform atp-bound state captured in active atpase cycle (340 kDa, Complex from Mus musculus)
hPAD4 bound to Activating Fab hA362
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8smk
Q-score: 0.419
Zhou X, Kong S, Maker A, Remesh SG, Leung KK, Verba KA, Wells JA
Nat Chem Biol (2024) 20 pp. 742-750 [ DOI: doi:10.1038/s41589-023-01535-8 Pubmed: 38308046 ]
- Protein-arginine deiminase type-4 (77 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Activating fab 362 heavy chain (24 kDa, Protein from Homo sapiens)
- Hpad4 bound to activating fab ha362 (248 kDa, Complex from Homo sapiens)
- Activating fab 362 light chain (23 kDa, Protein from Homo sapiens)
hPAD4 bound to inhibitory Fab hI365
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8sml
Q-score: 0.399
Zhou X, Kong S, Maker A, Remesh SG, Leung KK, Verba KA, Wells JA
Nat Chem Biol (2024) 20 pp. 742-750 [ DOI: doi:10.1038/s41589-023-01535-8 Pubmed: 38308046 ]
- Protein-arginine deiminase type-4 (77 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Fab hi365 light chain (23 kDa, Protein from Homo sapiens)
- Hpad4 bound to inhibitory fab hi365 (248 kDa, Complex from Homo sapiens)
- Fab hi365 heavy chain (24 kDa, Protein from Homo sapiens)
Cryo-EM map of zebrafish cardiac F-actin
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ord
Q-score: 0.415
Bradshaw M, Squire JM, Morris E, Atkinson G, Richardson R, Lees J, Caputo M, Bigotti GM, Paul DM
J.Muscle Res.Cell.Motil. (2023) 44 pp. 179-192 [ DOI: doi:10.1007/s10974-023-09653-5 Pubmed: 37480427 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin, alpha 1b, skeletal muscle (42 kDa, Protein from Danio rerio)
- Phosphate ion (94 Da, Ligand)
- Cardiac f-actin (Complex from Danio rerio)
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8fak
Q-score: 0.431
Duckworth AT, Ducos PL, McMillan SD, Satyshur KA, Blumenthal KH, Deorio HR, Larson JA, Sandler SJ, Grant T, Keck JL
Nat Commun (2023) 14 pp. 2725-2725 [ DOI: doi:10.1038/s41467-023-38144-x Pubmed: 37169801 ]
- Dna (5'-d(p*tp*cp*gp*gp*cp*gp*tp*gp*cp*tp*c)-3') (4 kDa, DNA from synthetic construct)
- Zinc ion (65 Da, Ligand)
- Complex of pria, prib, and replication fork (134 kDa, Complex from Escherichia coli)
- Dna (5'-d(p*cp*gp*gp*ap*tp*ap*ap*gp*gp*gp*cp*tp*gp*ap*gp*cp*ap*cp*gp*cp*cp*gp*a)-3') (12 kDa, DNA from synthetic construct)
- Primosomal replication protein n (11 kDa, Protein from Escherichia coli (strain K12))
- Dna (5'-d(p*cp*ap*gp*ap*cp*tp*cp*ap*tp*tp*tp*ap*gp*cp*cp*cp*tp*tp*ap*tp*cp*cp*g)-3') (12 kDa, DNA from synthetic construct)
- Primosomal protein n' (81 kDa, Protein from Escherichia coli (strain K12))