Lodwick JE, Shen R, Erramilli S, Xie Y, Roganowicz K, Kossiakoff AA, Zhao M
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.27.601040 Pubmed: 38979142 ]
- Major vault protein (99 kDa, Protein from Homo sapiens)
- Oligomerized human mvp (7 MDa, Complex from Homo sapiens)
Cryo-EM structure of Pseudomonas aeruginosa Recombinase A (RecA) in complex with LexAS125A mutant
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 8s7g
Q-score: 0.392
Vascon F, De Felice S, Gasparotto M, Huber ST, Catalano C, Chinellato M, Mezzetti R, Grinzato A, Filippini F, Maso L, Jakobi AJ, Cendron L
iScience (2025) 28 pp. 111726-111726 [ DOI: doi:10.1016/j.isci.2024.111726 Pubmed: 39898034 ]
- Magnesium ion (24 Da, Ligand)
- Lexa repressor (23 kDa, Protein from Pseudomonas aeruginosa)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Ssdna (Complex from synthetic construct)
- Cryo-em structure of pseudomonas aeruginosa recombinase a (reca) in complex with lexas125a mutant (Complex)
- Dna (36-mer) (10 kDa, DNA from synthetic construct)
- Recombinase a (reca) and lexa repressor (Complex from Pseudomonas aeruginosa)
- Protein reca (38 kDa, Protein from Pseudomonas aeruginosa)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8ymk
Q-score: 0.242
The mTORC1 cholesterol sensor LYCHOS (GPR155) - monomer with auxin
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8u5n
Q-score: 0.315
Bayly-Jones C, Lupton CJ, Keen AC, Dong S, Mastos C, Luo W, Qian C, Jones GD, Venugopal H, Chang YG, Clarke RJ, Halls ML, Ellisdon AM
Nature (2024) 634 pp. 1238-1244 [ DOI: doi:10.1038/s41586-024-08012-9 Pubmed: 39358511 ]
- Integral membrane protein gpr155 (99 kDa, Protein from Homo sapiens)
- Monomer of lychos (gpr155) (99 kDa, Complex from Homo sapiens)
- 1h-indol-3-ylacetic acid (175 Da, Ligand)
Fab 77-stabilized MeV F ectodomain fragment
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9at8
Q-score: 0.444
Zyla DS, Della Marca R, Niemeyer G, Zipursky G, Stearns K, Leedale C, Sobolik EB, Callaway HM, Hariharan C, Peng W, Parekh D, Marcink TC, Diaz Avalos R, Horvat B, Mathieu C, Snijder J, Greninger AL, Hastie KM, Niewiesk S, Moscona A, Porotto M, Ollmann Saphire E
Science (2024) 384 pp. eadm8693-eadm8693 [ DOI: doi:10.1126/science.adm8693 Pubmed: 38935733 ]
- Fab 77-stabilized mev f ectodomain fragment (43 kDa, Complex)
- Antibody 77 fab heavy chain, antibody 77 fab light chain (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mab 77 light chain (25 kDa, Protein from Homo sapiens)
- Measles virus fusion glycoprotein (Complex from Measles virus strain Ichinose-B95a)
- Fusion glycoprotein f0 (57 kDa, Protein from Measles virus strain Ichinose-B95a)
- Mab 77 heavy chain (52 kDa, Protein from Homo sapiens)
p97 (VCP) double mutant - F266A F539A
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8rs9
Q-score: 0.335
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
- Tertiary complex of the hexameric p97 f266a f539a double mutant (530 kDa, Complex from Homo sapiens)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
HIV Env BG505_MD39_B11 SOSIP boosting trimer in complex with B11_d77.7 mouse Fab and RM20A3 Fab
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8f92
Q-score: 0.516
Xie Z, Lin YC, Steichen JM, Ozorowski G, Kratochvil S, Ray R, Torres JL, Liguori A, Kalyuzhniy O, Wang X, Warner JE, Weldon SR, Dale GA, Kirsch KH, Nair U, Baboo S, Georgeson E, Adachi Y, Kubitz M, Jackson AM, Richey ST, Volk RM, Lee JH, Diedrich JK, Prum T, Falcone S, Himansu S, Carfi A, Yates 3rd JR, Paulson JC, Sok D, Ward AB, Schief WR, Batista FD
Science (2024) 384 pp. eadk0582-eadk0582 [ DOI: doi:10.1126/science.adk0582 Pubmed: 38753770 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- B11_d77.7 fab heavy chain (14 kDa, Protein from Mus musculus)
- Bg505_md39_b11 gp41 (18 kDa, Protein from Human immunodeficiency virus)
- Bg505_md39_b11 gp120 (54 kDa, Protein from Human immunodeficiency virus)
- Hiv-1 env bg505_md39_b11 sosip in complex with fabs b11_d77.7 and rm20a3 (Complex)
- Rm20a3 fab light chain (13 kDa, Protein from Macaca mulatta)
- Rm20a3 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- B11_d77.7 fab kappa light chain (11 kDa, Protein from Mus musculus)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8f9g
Q-score: 0.446
Xie Z, Lin YC, Steichen JM, Ozorowski G, Kratochvil S, Ray R, Torres JL, Liguori A, Kalyuzhniy O, Wang X, Warner JE, Weldon SR, Dale GA, Kirsch KH, Nair U, Baboo S, Georgeson E, Adachi Y, Kubitz M, Jackson AM, Richey ST, Volk RM, Lee JH, Diedrich JK, Prum T, Falcone S, Himansu S, Carfi A, Yates 3rd JR, Paulson JC, Sok D, Ward AB, Schief WR, Batista FD
Science (2024) 384 pp. eadk0582-eadk0582 [ DOI: doi:10.1126/science.adk0582 Pubmed: 38753770 ]
- Hiv env germline targeting bg505_md64_n332-gt5 sosip in complex with v3-glycan polyclonal fab isolated from immunized bg18hcgl knock-in mice v3-glycan epitope polyclonal fab heavy chain (Complex from Mus musculus)
- V3-glycan epitope polyclonal fab heavy chain (10 kDa, Protein from Mus musculus)
- Bg505_md64_n332-gt5 gp120 (54 kDa, Protein from synthetic construct)
- Bg505_md64_n332-gt5 gp41 (18 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- V3-glycan epitope polyclonal fab light chain (8 kDa, Protein from Mus musculus)
HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8vfv
Q-score: 0.495
Xie Z, Lin YC, Steichen JM, Ozorowski G, Kratochvil S, Ray R, Torres JL, Liguori A, Kalyuzhniy O, Wang X, Warner JE, Weldon SR, Dale GA, Kirsch KH, Nair U, Baboo S, Georgeson E, Adachi Y, Kubitz M, Jackson AM, Richey ST, Volk RM, Lee JH, Diedrich JK, Prum T, Falcone S, Himansu S, Carfi A, Yates 3rd JR, Paulson JC, Sok D, Ward AB, Schief WR, Batista FD
Science (2024) 384 pp. eadk0582-eadk0582 [ DOI: doi:10.1126/science.adk0582 Pubmed: 38753770 ]
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- B16_d77.5 mouse fab light chain fv (12 kDa, Protein from Mus musculus)
- Iv env bg505_md39_b16 sosip boosting trimer in complex with b16_d77.5 mouse fab and rm20a3 fab (Complex from Human immunodeficiency virus 1)
- B16_d77.5 mouse fab heavy chain fv (13 kDa, Protein from Mus musculus)
- Rm20a3 fab light chain (13 kDa, Protein from Macaca mulatta)
- Rm20a3 fab heavy chain (13 kDa, Protein from Macaca mulatta)