Resolution: 3.08 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gas
Q-score: 0.531
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ DOI: doi:10.1093/nar/gkae1211 Pubmed: 39673795 ]
- Complex np-rna (Complex)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Rna (Complex from synthetic construct)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Rna (5'-p(uc)9-fam3') (5 kDa, RNA from synthetic construct)
- Nucleoprotein (Complex from Influenza A virus)
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gat
Q-score: 0.437
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ DOI: doi:10.1093/nar/gkae1211 Pubmed: 39673795 ]
- Complex np-rna (Complex)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Rna (Complex from synthetic construct)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Rna (5'-p(uc)9-fam3') (5 kDa, RNA from synthetic construct)
- Nucleoprotein (Complex from Influenza A virus)
Resolution: 3.04 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gav
Q-score: 0.518
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ DOI: doi:10.1093/nar/gkae1211 Pubmed: 39673795 ]
- Complex np-rna (Complex)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Rna (Complex from synthetic construct)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Rna (5'-p(uc)9-fam3') (5 kDa, RNA from synthetic construct)
- Nucleoprotein (Complex from Influenza A virus)
Cryo-EM map of deposited and revitrified Hemagglutinin
Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ
bioRxiv (2024) [ Pubmed: 39605560 DOI: doi:10.1101/2024.11.21.624652 ]
- Hemagglutinin (170 kDa, Complex from Influenza A virus)
Cryo-EM map of shaped pulse revitrified Hemagglutinin
Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ
bioRxiv (2024) [ Pubmed: 39605560 DOI: doi:10.1101/2024.11.21.624652 ]
- Hemagglutinin (170 kDa, Complex from Influenza A virus)
Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85647
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9bdg
Q-score: 0.551
Maurer D, Ferreira Ramos AS, Bajic G, Aaron GS
To Be Published
- Ig-like domain-containing protein (23 kDa, Protein from Homo sapiens)
- Hemagglutinin (57 kDa, Protein from Influenza A virus)
- Fab adi-85647 heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza a virus hemagglutinin h3/darwin/6/2021 in complex with fab adi-85647 (350 kDa, Complex from Homo sapiens)
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ghk
Q-score: 0.507
Nagashima KA, Dzimianski JV, Yang M, Abendroth J, Sautto GA, Ross TM, DuBois RM, Edwards TE, Mousa JJ
Structure (2024) 32 pp. 1079- [ Pubmed: 38810648 DOI: doi:10.1016/j.str.2024.05.001 ]
- Hemagglutinin (53 kDa, Protein from Influenza A virus)
- Cryoem structure of influenza a virus a/melbourner/1/1946 (h1n1) hemagglutinin bound to gs10-x6-be4 fab (221 kDa, Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gs10-x6-be4 fab heavy chain (16 kDa, Protein from Homo sapiens)
- Gs10-x6-be4 fab light chain (13 kDa, Protein from Homo sapiens)
Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B.
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8r1j
Q-score: 0.501
Staller E, Carrique L, Swann OC, Fan H, Keown JR, Sheppard CM, Barclay WS, Grimes JM, Fodor E
Nat Commun (2024) 15 pp. 4123-4123 [ Pubmed: 38750014 DOI: doi:10.1038/s41467-024-48470-3 ]
- Polymerase basic protein 2 (101 kDa, Protein from Influenza A virus)
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus)
- Structure of avian h5n1 influenza a polymerase dimer in complex with human anp32b. (550 kDa, Complex from Influenza A virus)
- Polymerase acidic protein (82 kDa, Protein from Influenza A virus)
- Acidic leucine-rich nuclear phosphoprotein 32 family member b (28 kDa, Protein from Homo sapiens)
Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B (Consensus map)
Staller E, Carrique L, Swann OC, Fan H, Keown JR, Sheppard CM, Barclay WS, Grimes JM, Fodor E
Nat Commun (2024) 15 pp. 4123-4123 [ Pubmed: 38750014 DOI: doi:10.1038/s41467-024-48470-3 ]
Staller E, Carrique L, Swann OC, Fan H, Keown JR, Sheppard CM, Barclay WS, Grimes JM, Fodor E
Nat Commun (2024) 15 pp. 4123-4123 [ Pubmed: 38750014 DOI: doi:10.1038/s41467-024-48470-3 ]