Structure of the in situ yeast NPC
Resolution: 37.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7n9f
Q-score: 0.043
Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP
Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]
- Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup82 (82 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup159 (159 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin seh1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
- Dynein light chain 1, cytoplasmic (10 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup133 (133 kDa, Protein from Saccharomyces cerevisiae)
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin 145c (81 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
- Yeast npc (52 MDa, Cellular component from Saccharomyces cerevisiae)
- Nucleoporin asm4 (58 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
- Orphans bound to nup192 ntd (3 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
Structure of the SecY protein translocation channel in action
Resolution: 10.1 Å
EM Method: Single-particle
Fitted PDBs: 3j46
Q-score: 0.079
Park E, Menetret JF, Gumbart JC, Ludtke SJ, Li W, Whynot A, Rapoport TA, Akey CW
Nature (2014) 506 pp. 102-106 [ Pubmed: 24153188 DOI: doi:10.1038/nature12720 ]
- Membrane-bound 70s ribosome (2 MDa, Complex from Escherichia coli)
- Preprotein translocase (73 kDa, Protein from Escherichia coli)
- Transfer rna (25 kDa, RNA from Escherichia coli)
- S1p (61 kDa, Protein from Escherichia coli)
- Ribosome-nascent chain-secyeg complex (2 MDa, Sample)
Structure of the Drosophila apoptosome
Resolution: 6.9 Å
EM Method: Single-particle
Fitted PDBs: 4v4l
Q-score: 0.125
Yuan S, Yu X, Topf M, Dorstyn L, Kumar S, Ludtke SJ, Akey CW
Structure (2011) 19 pp. 128-140 [ DOI: doi:10.1016/j.str.2010.10.009 Pubmed: 21220123 ]
- Drosophila apoptosome (double ring) (2 MDa, Sample)
- Drosophila apaf-1 like protein (160 kDa, Protein from Drosophila melanogaster)