Cryo-EM reconstruction of PI3KC3-C1 in complex with Human RAB1A(Q70L)
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 9mhf
Q-score: 0.588
Cook ASI, Chen M, Ngyuen TN, Claveras-Cabezudo A, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH
To Be Published
- Phosphoinositide 3-kinase regulatory subunit 4 (158 kDa, Protein from Homo sapiens)
- Myristic acid (228 Da, Ligand)
- Ras-related protein rab-1a (25 kDa, Protein from Homo sapiens)
- Beclin 1-associated autophagy-related key regulator (55 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphatidylinositol-3 kinase class iii complex i bound to rab1a (384 kDa, Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Beclin-1 (51 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Phosphatidylinositol 3-kinase catalytic subunit type 3 (101 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9mhg
Q-score: 0.43
Cook ASI, Chen M, Ngyuen TN, Claveras-Cabezudo A, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH
To Be Published
- Phosphoinositide 3-kinase regulatory subunit 4 (158 kDa, Protein from Homo sapiens)
- Myristic acid (228 Da, Ligand)
- Ras-related protein rab-1a (25 kDa, Protein from Homo sapiens)
- Beclin 1-associated autophagy-related key regulator (55 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphatidylinositol-3 kinase class iii complex i bound to rab1a (384 kDa, Complex from Homo sapiens)
- Beclin-1 (51 kDa, Protein from Homo sapiens)
- Phosphatidylinositol 3-kinase catalytic subunit type 3 (101 kDa, Protein from Homo sapiens)
PI3KC3-C1 in complex with RAB1A. VPS34 kinase domain active conformation
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 9mhh
Q-score: 0.373
Cook ASI, Chen M, Ngyuen TN, Claveras-Cabezudo A, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH
To Be Published
- Phosphoinositide 3-kinase regulatory subunit 4 (158 kDa, Protein from Homo sapiens)
- Ras-related protein rab-1a (25 kDa, Protein from Homo sapiens)
- Beclin 1-associated autophagy-related key regulator (55 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphatidylinositol-3 kinase class iii complex i bound to rab1a (384 kDa, Complex from Homo sapiens)
- Beclin-1 (51 kDa, Protein from Homo sapiens)
- Phosphatidylinositol 3-kinase catalytic subunit type 3 (101 kDa, Protein from Homo sapiens)
Structure of the Ancestral Scaffold Antigen-5 of Coronavirus Spike protein
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 8aja
Q-score: 0.604
Hueting D, Schriever K, Sun R, Vlachiotis S, Zuo F, Du L, Persson H, Hofstrom C, Ohlin M, Wallden K, Buggert M, Hammarstrom L, Marcotte H, Pan-Hammarstrom Q, Andrell J, Syren PO
Nat Commun (2023) 14 pp. 6527-6527 [ DOI: doi:10.1038/s41467-023-42200-x Pubmed: 37845250 ]
Structure of the Ancestral Scaffold Antigen-6 of Coronavirus Spike protein
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8ajl
Q-score: 0.555
Hueting D, Schriever K, Sun R, Vlachiotis S, Zuo F, Du L, Persson H, Hofstrom C, Ohlin M, Wallden K, Buggert M, Hammarstrom L, Marcotte H, Pan-Hammarstrom Q, Andrell J, Syren PO
Nat Commun (2023) 14 pp. 6527-6527 [ DOI: doi:10.1038/s41467-023-42200-x Pubmed: 37845250 ]