Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody
Resolution: 10.2 Å
EM Method: Single-particle
Fitted PDBs: 8fe3
Q-score: 0.059
A Dowd K, Sirohi D, D Speer S, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC
PNAS (2023) 120 pp. e2218899120-e2218899120 [ Pubmed: 36638211 DOI: doi:10.1073/pnas.2218899120 ]
- Dengue virus 2 (Virus from Dengue virus 2)
- Prm12 fab heavy chain (24 kDa, Protein from Mus musculus)
- Envelope protein e (43 kDa, Protein from Dengue virus type 2)
- Prm12 fab light chain (23 kDa, Protein from Mus musculus)
- Prm protein (9 kDa, Protein from Dengue virus type 2)
Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody
Resolution: 9.8 Å
EM Method: Single-particle
Fitted PDBs: 8fe4
Q-score: 0.062
A Dowd K, Sirohi D, D Speer S, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC
PNAS (2023) 120 pp. e2218899120-e2218899120 [ Pubmed: 36638211 DOI: doi:10.1073/pnas.2218899120 ]
- Dengue virus 2 (Virus from Dengue virus 2)
- Prm13 fab light chain (23 kDa, Protein from Mus musculus)
- Prm13 fab heavy chain (23 kDa, Protein from Mus musculus)
- Envelope protein e (43 kDa, Protein from Dengue virus type 2)
- Prm protein (9 kDa, Protein from Dengue virus type 2)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7kcr
Q-score: 0.436
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ
Viruses (2020) 12 [ Pubmed: 33255202 DOI: doi:10.3390/v12121346 ]
- Adi30056 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Envelope protein e (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Monoclonal antibody adi30056 (Complex from Homo sapiens)
- Zika virus in complex with monoclonal antibody adi30056 (15 MDa, Complex)
- Adi30056 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Membrane protein m (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Native Mayaro virus cryo EM map, resolution 4.8 Angstroms
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6w2u
Q-score: 0.439
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699- [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- Spike glycoprotein e1 (41 kDa, Protein from Mayaro virus (strain Brazil))
- Native mayaro virus (Complex)
- Spike glycoprotein e2 (38 kDa, Protein from Mayaro virus (strain Brazil))
- Mayaro virus (Complex from Mayaro virus)
Resolution: 6.33 Å
EM Method: Single-particle
Fitted PDBs: 6vyv
Q-score: 0.339
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- Ross river virus (strain t48) (Virus from Ross river virus (strain T48))
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Ross river virus (strain T48))
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E1 glycoprotein (42 kDa, Protein from Ross river virus (strain T48))
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w09
Q-score: 0.34
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- E3 (6 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Virus from Chikungunya virus)
- Fab chk-265 (Complex from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (42 kDa, Protein from Chikungunya virus)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- Chikungunya virus-fab complex (Complex)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w1c
Q-score: 0.35
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- E2 glycoprotein (38 kDa, Protein from Mayaro virus (strain Brazil))
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- E1 glycoprotein (41 kDa, Protein from Mayaro virus (strain Brazil))
- Mayaro virus-fab chk-265 complex (Complex)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- Mayaro virus (Virus from Mayaro virus)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ DOI: doi:10.1073/pnas.1815432116 Pubmed: 30642974 ]
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
Structure of Zika virus at a resolution of 3.1 Angstrom
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6co8
Q-score: 0.507
Sevvana M, Long F, Miller AS, Klose T, Buda G, Sun L, Kuhn RJ, Rossmann MG
Structure (2018) 26 pp. 1169- [ DOI: doi:10.1016/j.str.2018.05.006 Pubmed: 29958768 ]
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- E protein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- M protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 5uhy
Q-score: 0.148
Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE, Kuhn RJ, Rossmann MG
Nat Commun (2017) 8 pp. 14722-14722 [ DOI: doi:10.1038/ncomms14722 Pubmed: 28300075 ]
- Zv67 fab chain 2 (23 kDa, Protein from Homo sapiens)
- Envelope protein (43 kDa, Protein from Zika virus)
- Zv67 fab chain 1 (23 kDa, Protein from Homo sapiens)
- Zika virus with zikv117 fab (Complex from Zika virus)