The complex structure of Omicron BA.1 RBD with BD604, S309,and S304
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7x1m
Q-score: 0.552
Huang M, Wu L, Zheng A, Xie Y, He Q, Rong X, Han P, Du P, Han P, Zhang Z, Zhao R, Jia Y, Li L, Bai B, Hu Z, Hu S, Niu S, Hu Y, Liu H, Liu B, Cui K, Li W, Zhao X, Liu K, Qi J, Wang Q, Gao GF
Immunity (2022) 55 pp. 1501-1514.e3 [ DOI: doi:10.1016/j.immuni.2022.06.005 Pubmed: 35777362 ]
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Bd604 fab, s309 fab and s304 fab complex with omicron ba.1 rbd (Complex)
- Bd-604 fab light chain (23 kDa, Protein from Homo sapiens)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- S309 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Bd-604 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Bd604 fab, s309 fab and s304 fab (Complex from Homo sapiens)
- Omicron ba.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- S304 fab haavy chain (23 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7we7
Q-score: 0.315
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab 282 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- Heavy chain of fab 282 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 282 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7we8
Q-score: 0.363
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Fab 265 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of fab 265 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of fab 265 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7we9
Q-score: 0.349
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- The light chain of fab xgv289 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab 289 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of fab xgv289 (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wea
Q-score: 0.421
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Fab xgv347 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7web
Q-score: 0.337
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 347 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wec
Q-score: 0.433
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 347 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv265
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7wee
Q-score: 0.415
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Fab 265 (Complex)
- The light chain of fab xgv265 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- The heavy chain of fab xgv265 (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv289
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7wef
Q-score: 0.46
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- The light chain of fab xgv289 (11 kDa, Protein from Homo sapiens)
- The heavy chain of fab xgv289 (13 kDa, Protein from Homo sapiens)
- Fab 289 (Complex from Homo sapiens)
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv347
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7wed
Q-score: 0.467
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron mutation spike protein (Complex from Homo sapiens)
- Fab 265 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)