Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 6o9z
Q-score: 0.441
Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A
Science (2019) 364 pp. 491-495 [ DOI: doi:10.1126/science.aaw2922 Pubmed: 31048491 ]
- Translation initiation factor eif-2b subunit alpha (33 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 2 subunit 1 (37 kDa, Protein from Homo sapiens)
- Translation initiation factor eif-2b subunit delta (57 kDa, Protein from Homo sapiens)
- Translation initiation factor eif-2b subunit gamma (50 kDa, Protein from Homo sapiens)
- Eif2 alpha-p bound to eif2b (Cellular component from Homo sapiens)
- Translation initiation factor eif-2b subunit beta (41 kDa, Protein from Homo sapiens)
- Translation initiation factor eif-2b subunit epsilon (80 kDa, Protein from Homo sapiens)
Undecorated GMPCPP microtubule
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6dpu
Q-score: 0.494
Zhang R, LaFrance B, Nogales E
PNAS (2018) 115 pp. E6191-E6200 [ Pubmed: 29915050 DOI: doi:10.1073/pnas.1802637115 ]
- Magnesium ion (24 Da, Ligand)
- Microtubule stabilized by gmpcpp (Complex from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6dpv
Q-score: 0.486
Zhang R, LaFrance B, Nogales E
PNAS (2018) 115 pp. E6191-E6200 [ Pubmed: 29915050 DOI: doi:10.1073/pnas.1802637115 ]
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Dynamic microtubule in gdp state (Complex from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
Undecorated GTPgammaS microtubule
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 6dpw
Q-score: 0.456
Zhang R, LaFrance B, Nogales E
PNAS (2018) 115 pp. E6191-E6200 [ Pubmed: 29915050 DOI: doi:10.1073/pnas.1802637115 ]
- Magnesium ion (24 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Gtpgammas-microtubule polymerized from gmpcpp-microtubule seeds (Complex from Sus scrofa)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Atomic resolution cryo-EM structure of beta-galactosidase
Resolution: 1.9 Å
EM Method: Single-particle
Fitted PDBs: 6cvm
Q-score: 0.7
Bartesaghi A, Aguerrebere C, Falconieri V, Banerjee S, Earl LA, Zhu X, Grigorieff N, Milne JLS, Sapiro G, Wu X, Subramaniam S
Structure (2018) 26 pp. 848- [ Pubmed: 29754826 DOI: doi:10.1016/j.str.2018.04.004 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- 2-phenylethyl 1-thio-beta-d-galactopyranoside (300 Da, Ligand)
- Escherichia coli beta-galactosidase bound to phenylethyl beta-d-thiogalactopyranoside (petg) (465 kDa, Complex from Escherichia coli K-12)
- Sodium ion (22 Da, Ligand)
- Beta-galactosidase (116 kDa, Protein from Escherichia coli (strain K12))
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6b70
Q-score: 0.374
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
eLife (2018) 7 [ DOI: doi:10.7554/eLife.33572 Pubmed: 29596046 ]
- Insulin-degrading enzyme (111 kDa, Protein from Homo sapiens)
- Insulin (11 kDa, Protein from Homo sapiens)
- Insulin degrading enzyme/insulin (100 kDa, Complex from Homo sapiens)
- Fab h11-e light chain (23 kDa, Protein from Homo sapiens)
- Fab h11-e heavy chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6b3q
Q-score: 0.394
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
eLife (2018) 7 [ DOI: doi:10.7554/eLife.33572 Pubmed: 29596046 ]
- Insulin degrading enzyme/insulin (100 kDa, Complex from Homo sapiens)
- Insulin-degrading enzyme (114 kDa, Protein from Homo sapiens)
- Insulin (11 kDa, Protein from Homo sapiens)
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6b44
Q-score: 0.478
Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P, Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ, Subramaniam S
Cell (2017) 171 pp. 414-426.e12 [ DOI: doi:10.1016/j.cell.2017.09.006 Pubmed: 28985564 ]
- Crispr-associated endonuclease cas6/csy4 (21 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))
- Pseudomonas aeruginosa strain smc4485 crispr repeat sequence (19 kDa, RNA from Pseudomonas aeruginosa)
- Target dna strand (41-mer) (15 kDa, DNA from synthetic construct)
- Crispr-associated protein csy3 (37 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))
- Crispr-associated protein csy1 (49 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))
- Non-target dna strand (5'-d(p*cp*ap*gp*tp*cp*ap*tp*cp*ap*cp*cp*ap*a)-3') (8 kDa, DNA from synthetic construct)
- Type i-f crispr crrna-guided csy surveillance complex with bound target dsdna (350 kDa, Complex from Pseudomonas aeruginosa)
- Crispr-associated protein csy2 (36 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6b46
Q-score: 0.487
Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P, Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ, Subramaniam S
Cell (2017) 171 pp. 414-426.e12 [ DOI: doi:10.1016/j.cell.2017.09.006 Pubmed: 28985564 ]
- Crispr-associated endonuclease cas6/csy4 (21 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))
- Pseudomonas aeruginosa strain smc4485 crispr repeat sequence (19 kDa, RNA from Pseudomonas aeruginosa)
- Type i-f crispr crrna-guided csy surveillance complex with bound anti-crispr protein acrf1 (350 kDa, Complex from Pseudomonas aeruginosa)
- Anti-crispr protein acrf1 (8 kDa, Protein from Pseudomonas phage JBD30)
- Crispr-associated protein csy3 (37 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))
Yeast tubulin polymerized with GTP in vitro
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 5w3f
Q-score: 0.366
Howes SC, Geyer EA, LaFrance B, Zhang R, Kellogg EH, Westermann S, Rice LM, Nogales E
J Cell Biol (2017) 216 pp. 2669-2677 [ Pubmed: 28652389 DOI: doi:10.1083/jcb.201612195 ]
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Dynamic microtubule lattice (Complex from Saccharomyces cerevisiae S288c)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Tubulin alpha-1 chain (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))