Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6nbf
Q-score: 0.444
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y
Science (2019) 364 pp. 148-153 [ Pubmed: 30975883 DOI: doi:10.1126/science.aav7942 ]
- Parathyroid hormone/parathyroid hormone-related peptide receptor (54 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Palmitic acid (256 Da, Ligand)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Cryo-em structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and g protein (Complex from Homo sapiens)
- Gs protein alpha subunit (43 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Long-acting parathyroid hormone analog (4 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6nbh
Q-score: 0.347
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y
Science (2019) 364 pp. 148-153 [ Pubmed: 30975883 DOI: doi:10.1126/science.aav7942 ]
- Parathyroid hormone/parathyroid hormone-related peptide receptor (54 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Palmitic acid (256 Da, Ligand)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Cryo-em structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and g protein (Complex from Homo sapiens)
- Gs protein alpha subunit (43 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Long-acting parathyroid hormone analog (4 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6nbi
Q-score: 0.285
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y
Science (2019) 364 pp. 148-153 [ Pubmed: 30975883 DOI: doi:10.1126/science.aav7942 ]
- Parathyroid hormone/parathyroid hormone-related peptide receptor (54 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Cryo-em structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and g protein (Complex from Homo sapiens)
- Gs protein alpha subunit (43 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Long-acting parathyroid hormone analog (4 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Single-particle cryo-EM reconstruction of horse liver alcohol dehydrogenase using 200 keV
Nat Commun (2019) 10 pp. 1032-1032 [ Pubmed: 30833564 DOI: doi:10.1038/s41467-019-08991-8 ]
- Alcohol dehydrogenase from equine liver (81 kDa, Complex from Equus caballus)
- Zinc ion (65 Da, Ligand)
- Alcohol dehydrogenase e chain (39 kDa, Protein from Equus caballus)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
Single-particle cryo-EM reconstruction of human methemoglobin using 200 keV, state 1
Nat Commun (2019) 10 pp. 1032-1032 [ Pubmed: 30833564 DOI: doi:10.1038/s41467-019-08991-8 ]
- Hemoglobin subunit beta (15 kDa, Protein from Homo sapiens)
- Methemoglobin from human (64 kDa, Complex from Homo sapiens)
- Hemoglobin subunit alpha (14 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Single-particle cryo-EM reconstruction of human methemoglobin using 200 keV, state 2
Nat Commun (2019) 10 pp. 1032-1032 [ Pubmed: 30833564 DOI: doi:10.1038/s41467-019-08991-8 ]
- Hemoglobin subunit beta (15 kDa, Protein from Homo sapiens)
- Human methemoglobin (64 kDa, Complex from Homo sapiens)
- Hemoglobin subunit alpha (14 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Cryo-EM structure of beta-galactosidase using RELION on Amazon Web Services
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 6drv
Q-score: 0.661
Cianfrocco MA, Lahiri I, DiMaio F, Leschziner AE
J Struct Biol (2018) 203 pp. 230-235 [ DOI: doi:10.1016/j.jsb.2018.05.014 Pubmed: 29864529 ]
- Beta-galactosidase (116 kDa, Protein from Escherichia coli (strain K12))
- Beta-galactosidase (466 MDa, Complex from Escherichia coli)
Structure of photosystem I supercomplex with light-harvesting complexes I and II
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 5zji
Q-score: 0.494
Pan X, Ma J, Su X, Cao P, Chang W, Liu Z, Zhang X, Li M
Science (2018) 360 pp. 1109-1113 [ Pubmed: 29880686 DOI: doi:10.1126/science.aat1156 ]
- Photosystem i reaction center subunit ix (4 kDa, Protein from Maize)
- Beta-carotene (536 Da, Ligand)
- Chlorophyll a-b binding protein, chloroplastic (29 kDa, Protein from Maize)
- (1r,3r)-6-{(3e,5e,7e,9e,11e,13e,15e,17e)-18-[(1s,4r,6r)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (600 Da, Ligand)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Maize)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Photosystem i reaction center subunit iv a (14 kDa, Protein from Maize)
- Photosystem i reaction center subunit ii (21 kDa, Protein from Maize)
- Iron/sulfur cluster (351 Da, Ligand)
- Supercomplex of plant psi-lhci-lhcii from zea mays (Complex from Zea mays)
- Photosystem i reaction center subunit psak (13 kDa, Protein from Maize)
- Chlorophyll a-b binding protein, chloroplastic (24 kDa, Protein from Maize)
- Chlorophyll a-b binding protein, chloroplastic (27 kDa, Protein from Maize)
- Chlorophyll b (907 Da, Ligand)
- Photosystem i reaction center subunit iii (23 kDa, Protein from Maize)
- Chlorophyll a-b binding protein, chloroplastic (26 kDa, Protein from Maize)
- 16kda membrane protein (14 kDa, Protein from Maize)
- Dodecyl-alpha-d-maltoside (510 Da, Ligand)
- Chlorophyll a-b binding protein 1, chloroplastic (24 kDa, Protein from Maize)
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from maize)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Photosystem i reaction center subunit xi (22 kDa, Protein from Maize)
- Photosystem i reaction center subunit n (15 kDa, Protein from Maize)
- Photosystem i reaction center subunit v (15 kDa, Protein from Maize)
- Phylloquinone (450 Da, Ligand)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Chlorophyll a (893 Da, Ligand)
- Photosystem i reaction center subunit vi, chloroplastic (14 kDa, Protein from Maize)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i subunit vii (8 kDa, Protein from maize)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Maize)
- Chlorophyll a isomer (893 Da, Ligand)
- Chlorophyll a-b binding protein, chloroplastic (29 kDa, Protein from Maize)
Human nuclear exosome-MTR4 RNA complex - overall reconstruction
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 6d6q
Q-score: 0.413
Weick EM, Puno MR, Januszyk K, Zinder JC, DiMattia MA, Lima CD
Cell (2018) 173 pp. 1663- [ Pubmed: 29906447 DOI: doi:10.1016/j.cell.2018.05.041 ]
- Exosome complex component rrp46 (25 kDa, Protein from Homo sapiens)
- Exosome complex component mtr3 (28 kDa, Protein from Homo sapiens)
- Exosome complex component rrp40 (29 kDa, Protein from Homo sapiens)
- Exosome complex component rrp42 (32 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- M-phase phosphoprotein 6 (19 kDa, Protein from Homo sapiens)
- Dna/rna (62-mer) (19 kDa, Macromolecule from synthetic construct)
- Human nuclear exosome-mtr4 helicase captured after unwinding a dna/rna substrate (690 kDa, Complex from Homo sapiens)
- Exosome rna helicase mtr4 (118 kDa, Protein from Homo sapiens)
- Exosome complex component rrp45 (52 kDa, Protein from Homo sapiens)
- Exosome component 10 (86 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Exosome complex component rrp43 (30 kDa, Protein from Homo sapiens)
- Rna (5'-r(*ap*gp*cp*ap*cp*cp*gp*up*ap*ap*ap*gp*ap*cp*gp*c)-3') (5 kDa, RNA from synthetic construct)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Exosome complex component csl4 (21 kDa, Protein from Homo sapiens)
- Exosome complex exonuclease rrp44 (109 kDa, Protein from Homo sapiens)
- Exosome complex component rrp41 (26 kDa, Protein from Homo sapiens)
- Exosome complex component rrp4 (33 kDa, Protein from Homo sapiens)
Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 6d6r
Q-score: 0.456
Weick EM, Puno MR, Januszyk K, Zinder JC, DiMattia MA, Lima CD
Cell (2018) 173 pp. 1663- [ Pubmed: 29906447 DOI: doi:10.1016/j.cell.2018.05.041 ]
- Exosome complex component rrp46 (25 kDa, Protein from Homo sapiens)
- Exosome complex component mtr3 (28 kDa, Protein from Homo sapiens)
- Exosome complex component rrp40 (29 kDa, Protein from Homo sapiens)
- Exosome complex component rrp42 (32 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- M-phase phosphoprotein 6 (19 kDa, Protein from Homo sapiens)
- Dna/rna (62-mer) (19 kDa, Macromolecule from synthetic construct)
- Human nuclear exosome-mtr4 helicase captured after unwinding a dna/rna substrate (690 kDa, Complex from Homo sapiens)
- Exosome rna helicase mtr4 (118 kDa, Protein from Homo sapiens)
- Exosome complex component rrp45 (52 kDa, Protein from Homo sapiens)
- Exosome component 10 (86 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Exosome complex component rrp43 (30 kDa, Protein from Homo sapiens)
- Rna (5'-r(*ap*gp*cp*ap*cp*cp*gp*up*ap*ap*ap*gp*ap*cp*gp*c)-3') (5 kDa, RNA from synthetic construct)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Exosome complex component csl4 (21 kDa, Protein from Homo sapiens)
- Exosome complex exonuclease rrp44 (109 kDa, Protein from Homo sapiens)
- Exosome complex component rrp41 (26 kDa, Protein from Homo sapiens)
- Exosome complex component rrp4 (33 kDa, Protein from Homo sapiens)