The reconstruction of biotin-bound streptavidin at 3.2 Angstrom resolution
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6j6j
Q-score: 0.517
Fan X, Wang J, Zhang X, Yang Z, Zhang JC, Zhao L, Peng HL, Lei J, Wang HW
Nat Commun (2019) 10 pp. 2386-2386 [ Pubmed: 31160591 DOI: doi:10.1038/s41467-019-10368-w ]
- Biotin (244 Da, Ligand)
- Water (18 Da, Ligand)
- Streptavidin with biotin (52 kDa, Complex from Streptomyces avidinii)
- Streptavidin (12 kDa, Protein from Streptomyces avidinii)
Structure of the human frataxin-bound iron-sulfur cluster assembly complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6nzu
Q-score: 0.546
Fox NG, Yu X, Feng X, Bailey HJ, Martelli A, Nabhan JF, Strain-Damerell C, Bulawa C, Yue WW, Han S
Nat Commun (2019) 10 pp. 2210-2210 [ Pubmed: 31101807 DOI: doi:10.1038/s41467-019-09989-y ]
- The human frataxin-bound iron-sulfur cluster assembly complex (186 kDa, Complex from Homo sapiens)
- Cysteine desulfurase, mitochondrial (44 kDa, Protein from Homo sapiens)
- Acyl carrier protein (8 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Frataxin, mitochondrial (14 kDa, Protein from Homo sapiens)
- Lyr motif-containing protein 4 (10 kDa, Protein from Homo sapiens)
- Iron-sulfur cluster assembly enzyme iscu, mitochondrial (13 kDa, Protein from Homo sapiens)
CryoEM Density of Acetylated Microtubules
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 6o2q
Q-score: 0.428
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E
PNAS (2019) 116 pp. 10366-10371 [ Pubmed: 31072936 DOI: doi:10.1073/pnas.1900441116 ]
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Acetylated microtubule (Tissue from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6o2r
Q-score: 0.461
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E
PNAS (2019) 116 pp. 10366-10371 [ Pubmed: 31072936 DOI: doi:10.1073/pnas.1900441116 ]
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Deacetylated microtubule (Tissue from Sus scrofa)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6jb1
Q-score: 0.406
Ding D, Wang M, Wu JX, Kang Y, Chen L
Cell Rep (2019) 27 pp. 1848-1857.e4 [ Pubmed: 31067468 DOI: doi:10.1016/j.celrep.2019.04.050 ]
- Repaglinide (452 Da, Ligand)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Atp-binding cassette sub-family c member 8 isoform x2 (177 kDa, Protein from Mesocricetus auratus)
- Phosphatidylethanolamine (734 Da, Ligand)
- Atp-sensitive inward rectifier potassium channel 11 (43 kDa, Protein from Mus musculus)
- Digitonin (1 kDa, Ligand)
- Katp (Complex from Mus musculus)
The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6r3q
Q-score: 0.444
Qi C, Sorrentino S, Medalia O, Korkhov VM
Science (2019) 364 pp. 389-394 [ Pubmed: 31023924 DOI: doi:10.1126/science.aav0778 ]
- Adenylate cyclase 9 (182 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (46 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
- Complex of adenylyl cyclase ac9 with g protein subunit galphas (Complex)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex from Bos taurus)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
- Adenylate cyclase 9 (Complex from Bos taurus)
Structure of a soluble domain of adenylyl cyclase bound to an activatedstimulatory G protein
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6r4p
Q-score: 0.51
Qi C, Sorrentino S, Medalia O, Korkhov VM
Science (2019) 364 pp. 389-394 [ Pubmed: 31023924 DOI: doi:10.1126/science.aav0778 ]
- Adenylate cyclase 9 (182 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (46 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
- Complex of adenylyl cyclase ac9 with g protein subunit galphas (Complex)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex from Bos taurus)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
- Adenylate cyclase 9 (Complex from Bos taurus)
Muscarinic acetylcholine receptor 1-G11 protein complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6oij
Q-score: 0.504
Maeda S, Qu Q, Robertson MJ, Skiniotis G, Kobilka BK
Science (2019) 364 pp. 552-557 [ Pubmed: 31073061 DOI: doi:10.1126/science.aaw5188 ]
- Muscarinic acetylcholine receptor 1 in complex with heterotrimeric g11 protein (150 kDa, Complex)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein subunit alpha-11 (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-n,n,n-trimethylbut-2-yn-1-aminium (197 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein subunit alpha-11, antibody fragment, guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Antibody fragment (27 kDa, Protein from Mus musculus)
- Muscarinic acetylcholine receptor m1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Muscarinic acetylcholine receptor m1 (41 kDa, Protein from Homo sapiens)
Muscarinic acetylcholine receptor 2-Go complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6oik
Q-score: 0.464
Maeda S, Qu Q, Robertson MJ, Skiniotis G, Kobilka BK
Science (2019) 364 pp. 552-557 [ Pubmed: 31073061 DOI: doi:10.1126/science.aaw5188 ]
- Guanine nucleotide-binding protein g(o) subunit alpha (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha, guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2, antibody fragment (Complex from Homo sapiens)
- Muscarinic acetylcholine receptor m2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-n,n,n-trimethylbut-2-yn-1-aminium (197 Da, Ligand)
- Antibody fragment (27 kDa, Protein from Mus musculus)
- 3-amino-5-chloro-n-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide (437 Da, Ligand)
- Muscarinic acetylcholine receptor 2 in complex with heterotrimeric goa protein (150 kDa, Complex)
- Muscarinic acetylcholine receptor m2,muscarinic acetylcholine receptor m2 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6j6g
Q-score: 0.317
Wan R, Bai R, Yan C, Lei J, Shi Y
Cell (2019) 177 pp. 339-351.e13 [ Pubmed: 30879786 DOI: doi:10.1016/j.cell.2019.02.006 ]
- Pre-mrna-splicing factor bud31 (18 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor syf2 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor prp46 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor cwc15 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor syf1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae S288c)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor cwc2 (38 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Catalytically activated spliceosome b*-a2 complex (Complex from Saccharomyces cerevisiae S288c)
- Pre-mrna-splicing factor cef1 (67 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor cwc22 (67 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor slt11 (40 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor snt309 (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing protein 45 (42 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae S288c)
- Pre-mrna-splicing factor clf1 (82 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae S288c)
- Pre-mrna-processing factor 17 (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor isy1 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor snu114 (114 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-splicing factor cwc21 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Inositol hexakisphosphate (660 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Act1 pre-mrna (217 kDa, RNA from Saccharomyces cerevisiae S288c)
- Pre-mrna-splicing factor 8 (279 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing factor 19 (56 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))