Cryo-EM Structure of FBOX22-BACH1BTB
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8ua3
Q-score: 0.422
Cao S, Garcia SF, Shi H, James EI, Kito Y, Shi H, Mao H, Kaisari S, Rona G, Deng S, Goldberg HV, Ponce J, Ueberheide B, Lignitto L, Guttman M, Pagano M, Zheng N
Cell (2024) 187 pp. 7568-7584.e22 [ Pubmed: 39504958 DOI: doi:10.1016/j.cell.2024.10.012 ]
- Fbxo22-bach1btb (Complex from Homo sapiens)
- Transcription regulator protein bach1 (13 kDa, Protein from Homo sapiens)
- F-box only protein 22 (44 kDa, Protein from Homo sapiens)
Cryo-EM Structure of SCF-FBOX22-BACH1BTB
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ua6
Q-score: 0.359
Cao S, Garcia SF, Shi H, James EI, Kito Y, Shi H, Mao H, Kaisari S, Rona G, Deng S, Goldberg HV, Ponce J, Ueberheide B, Lignitto L, Guttman M, Pagano M, Zheng N
Cell (2024) 187 pp. 7568-7584.e22 [ Pubmed: 39504958 DOI: doi:10.1016/j.cell.2024.10.012 ]
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)
- Transcription regulator protein bach1 (13 kDa, Protein from Homo sapiens)
- Cullin-1 (88 kDa, Protein from Homo sapiens)
- F-box only protein 22 (44 kDa, Protein from Homo sapiens)
- Fbxo22-bach1btb (Complex from Homo sapiens)
Structure of SCF-FBXL17-BACH1BTB E3 ligase complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ubt
Q-score: 0.405
Cao S, Garcia SF, Shi H, James EI, Kito Y, Shi H, Mao H, Kaisari S, Rona G, Deng S, Goldberg HV, Ponce J, Ueberheide B, Lignitto L, Guttman M, Pagano M, Zheng N
Cell (2024) 187 pp. 7568-7584.e22 [ Pubmed: 39504958 DOI: doi:10.1016/j.cell.2024.10.012 ]
- Transcription regulator protein bach1 (13 kDa, Protein from Homo sapiens)
- Cullin-1 (88 kDa, Protein from Homo sapiens)
- F-box/lrr-repeat protein 17 (44 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)
- The scf-f-box protein with bach1 btb domain, scf-bfxl17-bach1btb (Complex from Homo sapiens)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 9deq
Q-score: 0.254
Adair BD, Field CO, Alonso JL, Xiong JP, Deng SX, Ahn HS, Mashin E, Clish CB, van Agthoven J, Yeager M, Guo Y, Tess DA, Landry DW, Poncz M, Arnaout MA
Nat Commun (2024) 15 pp. 8612-8612 [ Pubmed: 39366965 DOI: doi:10.1038/s41467-024-52869-3 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Integrin alpha-iib (110 kDa, Protein from Homo sapiens)
- N-(1,3-benzoxazole-2-carbonyl)-o-[4-(piperidin-4-yl)butyl]-l-tyrosine (465 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Full length integrin alphaiibbeta3 (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Integrin beta-3 (84 kDa, Protein from Homo sapiens)
Cryo-EM Structures of Full-Length Integrin alphaIIbbeta3 in Native Lipids Complexed with Tirofiban
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 9der
Q-score: 0.232
Adair BD, Field CO, Alonso JL, Xiong JP, Deng SX, Ahn HS, Mashin E, Clish CB, van Agthoven J, Yeager M, Guo Y, Tess DA, Landry DW, Poncz M, Arnaout MA
Nat Commun (2024) 15 pp. 8612-8612 [ Pubmed: 39366965 DOI: doi:10.1038/s41467-024-52869-3 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Full-length integrin alphaiibbeta3 (Complex from Homo sapiens)
- Integrin alpha-iib (110 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Integrin beta-3 (84 kDa, Protein from Homo sapiens)
- Tirofiban (440 Da, Ligand)
Structure of mouse SCMC-14-3-3gama complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xi3
Q-score: 0.532
Chi P, Han Z, Jiao H, Li J, Wang X, Hu H, Deng D
To Be Published
- Mouse scmc-14-3-3gama complex (Complex from Mus musculus)
- Transducin-like enhancer protein 6 (62 kDa, Protein from Mus musculus)
- 14-3-3 protein gamma (28 kDa, Protein from Mus musculus)
- Oocyte-expressed protein homolog (19 kDa, Protein from Mus musculus)
- Nacht, lrr and pyd domains-containing protein 5 (119 kDa, Protein from Mus musculus)
Structure of acyltransferase GWT1 in complex with manogepix(APX001A)
Pfr conformer of Arabidopsis thaliana phytochrome B in complex with phytochrome-interacting factor 6
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8yb4
Q-score: 0.522
Wang Z, Wang W, Zhao D, Song Y, Lin X, Shen M, Chi C, Xu B, Zhao J, Deng XW, Wang J
Cell (2024) 187 pp. 6235-6250.e19 [ DOI: doi:10.1016/j.cell.2024.09.005 Pubmed: 39317197 ]
- Complex of atphyb-pfr homodimer (Complex from Arabidopsis thaliana)
- Phytochrome-interacting factor 6 (11 kDa, Protein from Arabidopsis thaliana)
- Pif6 monomer (Complex)
- Ternary complex of atphyb-pfr homodimer with atpif6 (120 kDa, Complex from Arabidopsis thaliana)
- 3-[5-[[(3~{r},4~{r})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{h}-pyrrol-2-yl]methyl]-4-methyl-1~{h}-pyrrol-3-yl]propanoic acid (586 Da, Ligand)
- Phytochrome b (129 kDa, Protein from Arabidopsis thaliana)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 9ipu
Q-score: 0.237
Shi Q, Deng ZH, Zhang LY, Tong ZB, Chu G-C, Ai HS, Liu L
To Be Published
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)
- Dna (171-mer) (52 kDa, DNA from Homo sapiens)
- Ubiquitin-conjugating enzyme e2 d3 (16 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rnf168 (22 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2b type 1-k (13 kDa, Protein from Homo sapiens)
- Dna (171-mer) (52 kDa, DNA from Homo sapiens)
- Histone h1.0 (20 kDa, Protein from Homo sapiens)
- Cryo-em structure of the rnf168(1-193)/ubch5c-ub ubiquitylation module bound to h1.0-k63-ub3 modified chromatosome (Complex from Homo sapiens)