Cryo-EM structure of the E. coli BrxX methyltransferase complexed with Ocr
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8uy7
Q-score: 0.562
Zeinert R, Zhou F, Cavalcanti Franco PH, Zoeller J, Lessen H, Iyer A, Langer JD, Sodt AJ, Storz G, Matthies D
To Be Published
- Water (18 Da, Ligand)
- Magnesium transporter mgta from escherichia coli in the dimeric form in the presence of 5 mm mgcl2 (201 kDa, Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Magnesium-transporting atpase, p-type 1 (100 kDa, Protein from Escherichia coli)
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 in C1
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8uy8
Q-score: 0.546
Zeinert R, Zhou F, Cavalcanti Franco PH, Zoeller J, Lessen H, Iyer A, Langer JD, Sodt AJ, Storz G, Matthies D
To Be Published
- Water (18 Da, Ligand)
- Magnesium transporter mgta from escherichia coli in the dimeric form in the presence of 5 mm mgcl2 without symmetry applied (c1) (201 kDa, Complex from Escherichia coli)
- Magnesium-transporting atpase, p-type 1 (100 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
Magnesium transporter MgtA monomer from E. coli in 5 mM MgCl2
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 8uy9
Q-score: 0.405
Zeinert R, Zhou F, Cavalcanti Franco PH, Zoeller J, Lessen H, Iyer A, Langer JD, Sodt AJ, Storz G, Matthies D
To Be Published
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ATP
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8uya
Q-score: 0.48
Zeinert R, Zhou F, Cavalcanti Franco PH, Zoeller J, Lessen H, Iyer A, Langer JD, Sodt AJ, Storz G, Matthies D
To Be Published
- Water (18 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium-transporting atpase, p-type 1 (100 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Magnesium transporter mgta from escherichia coli in the dimeric form in the presence of 5 mm mgcl2 and 5 mm atp (201 kDa, Complex from Escherichia coli)
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ATPyS
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 8uyb
Q-score: 0.394
Zeinert R, Zhou F, Cavalcanti Franco PH, Zoeller J, Lessen H, Iyer A, Langer JD, Sodt AJ, Storz G, Matthies D
To Be Published
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Magnesium-transporting atpase, p-type 1 (100 kDa, Protein from Escherichia coli)
- Magnesium transporter mgta from escherichia coli in the dimeric form in the presence of 5 mm mgcl2 and 5 mm atpys (201 kDa, Complex from Escherichia coli)
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ADP
Resolution: 3.75 Å
EM Method: Single-particle
Fitted PDBs: 8uyc
Q-score: 0.431
Zeinert R, Zhou F, Cavalcanti Franco PH, Zoeller J, Lessen H, Iyer A, Langer JD, Sodt AJ, Storz G, Matthies D
To Be Published
Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9ivg
Q-score: 0.48
Li J, Li G, Mai Y, Liu X, Yang D, Zhou Q, Wang MW
Acta Pharm Sin B (2024) 14 pp. 5069-5073 [ DOI: doi:10.1016/j.apsb.2024.09.002 Pubmed: 39664415 ]
- Cryo-em structure of the glp-1(9-36)-bound human glp-1r-gs complex (Complex from Homo sapiens)
- Glp-1(9-36) (3 kDa, Protein from Homo sapiens)
- Nanobody-35 (15 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Glucagon-like peptide 1 receptor (50 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
Cryo-EM structure of CB2-G protein complex
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8x3l
Q-score: 0.474
Yang X, Zhou P, Shen S, Hu Q, Tian C, Xia A, Wang Y, Yang Z, Nan J, Zhou Y, Chen S, Tian X, Wu C, Lin G, Zhang L, Wang K, Zheng T, Zou J, Yan W, Shao Z, Yang S
PNAS (2024) 121 pp. e2401091121-e2401091121 [ Pubmed: 39024109 DOI: doi:10.1073/pnas.2401091121 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
- 4-[3-(4-fluoranyl-2~{h}-indazol-7-yl)-1,2,4-oxadiazol-5-yl]-1-(4-fluorophenyl)azepan-2-one (409 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Yl025-bound cb2r in complex with gi heterotrimer (Complex)
- Cb2r-gi (Complex from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Cannabinoid receptor 2 (35 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Structure of human pyruvate carboxylase
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8xl9
Q-score: 0.559
Zhou FY, Zhang YY, Zhu Y, Zhou Q, Shi Y, Hu Q
eLife (2024) [ DOI: doi:10.7554/eLife.98885.2 ]
- Biotin (244 Da, Ligand)
- Pyruvate carboxylase, mitochondrial (129 kDa, Protein from Homo sapiens)
- Homotetramer complex of human pyruvate carboxylase (Complex from Homo sapiens)