Complex of AMPPNP-Kif7 and Gli2 Zinc-Finger domain bound to microtubules
Resolution: 3.89 Å
EM Method: Helical reconstruction
Fitted PDBs: 7rx0
Q-score: 0.338
Haque F, Freniere C, Ye Q, Mani N, Wilson-Kubalek EM, Ku PI, Milligan RA, Subramanian R
Nat Cell Biol (2022) 24 pp. 1088-1098 [ Pubmed: 35725768 DOI: doi:10.1038/s41556-022-00935-7 ]
- Zinc finger protein gli2 (7 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Microtubules (Complex from Sus scrofa)
- Tubulin alpha-1a chain (50 kDa, Protein from Sus scrofa)
- Microtubule-bound complex of kif7 and gli2 zinc finger domain (Complex)
- Kinesin-like protein kif7 (59 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin kif7 (Complex from Homo sapiens)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Zinc-finger protein gli2 (Complex from Homo sapiens)
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
Resolution: 8.5 Å
EM Method: Single-particle
Fitted PDBs: 6xob
Q-score: 0.182
Williamson LE, Gilliland Jr T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe Jr JE
Cell (2020) 183 pp. 1884-1900.e23 [ Pubmed: 33301709 DOI: doi:10.1016/j.cell.2020.11.011 ]
- Togavirin (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-143 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Togavirin (29 kDa, Protein from Eastern equine encephalitis virus)
- Togavirin (47 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Eeev-143 fab light chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of microtubule-bound Kif7 in the ADP state
Resolution: 4.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 6mlq
Q-score: 0.283
Jiang S, Mani N, Wilson-Kubalek EM, Ku PI, Milligan RA, Subramanian R
Dev Cell (2019) 49 pp. 711-730.e8 [ Pubmed: 31031197 DOI: doi:10.1016/j.devcel.2019.04.001 ]
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1a chain (50 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Taxol (853 Da, Ligand)
- Microtubule-bound kif7 (Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Kinesin-like protein kif7 (43 kDa, Protein from Homo sapiens)
Cryo-EM structure of microtubule-bound Kif7 in the AMPPNP state
Resolution: 4.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 6mlr
Q-score: 0.303
Jiang S, Mani N, Wilson-Kubalek EM, Ku PI, Milligan RA, Subramanian R
Dev Cell (2019) 49 pp. 711-730.e8 [ Pubmed: 31031197 DOI: doi:10.1016/j.devcel.2019.04.001 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Tubulin alpha-1a chain (50 kDa, Protein from Sus scrofa)
- Taxol (853 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Microtubule-bound kif7 (Complex from sus scrofa)
- Kinesin-like protein kif7 (43 kDa, Protein from Homo sapiens)
cryo-EM structure of human TRPML1 with PI35P2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6e7p
Q-score: 0.447
Nat Commun (2018) 9 pp. 4192-4192 [ Pubmed: 30305615 DOI: doi:10.1038/s41467-018-06493-7 ]
cryo-EM structure of human TRPML1 with PI45P2
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 6e7y
Q-score: 0.431
Nat Commun (2018) 9 pp. 4192-4192 [ Pubmed: 30305615 DOI: doi:10.1038/s41467-018-06493-7 ]
cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 6e7z
Q-score: 0.392
Nat Commun (2018) 9 pp. 4192-4192 [ Pubmed: 30305615 DOI: doi:10.1038/s41467-018-06493-7 ]
- 2-{2-oxo-2-[(4s)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2h)-yl]ethyl}-1h-isoindole-1,3(2h)-dione (362 Da, Ligand)
- Mucolipin-1 (65 kDa, Protein from Homo sapiens)
- (1r,2s,3s,4r,5s,6r)-5-{[(r)-[(2r)-2,3-bis{[(1s)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)] (750 Da, Ligand)
- Trpml1 (Complex from Homo sapiens)
Structure of the SLC4 transporter Bor1p in an inward-facing conformation
Resolution: 5.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 5sv9
Q-score: 0.249
Coudray N, L Seyler S, Lasala R, Zhang Z, Clark KM, Dumont ME, Rohou A, Beckstein O, Stokes DL
Protein Sci (2017) 26 pp. 130-145 [ DOI: doi:10.1002/pro.3061 Pubmed: 27717063 ]
- Bor1p boron transporter (53 kDa, Protein from Saccharomyces mikatae)
- Bor1p dimer in an inward-facing conformation (60 kDa, Complex from Saccharomyces mikatae)