Cryo-EM structure of Prefusion-stabilized RSV F (DS-Cav1) in complex with Fab AM14
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7mpg
Q-score: 0.348
Harshbarger W, Abeyrathne PD, Tian S, Huang Y, Chandramouli S, Bottomley MJ, Malito E
MABs () 13 pp. 1955812-1955812 [ DOI: doi:10.1080/19420862.2021.1955812 Pubmed: 34420474 ]
- Homo sapiens respiratory syncytial virus a (285 kDa, Complex)
- Am14 fab light chain (25 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f1 and f2 fused with fibritin trimerization domain. (Complex from Respiratory syncytial virus A2)
- Fusion glycoprotein f0,envelope glycoprotein (54 kDa, Protein from Human immunodeficiency virus 1)
- Fab am14 heavy and light chain (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Am14 fab heavy chain (26 kDa, Protein from Homo sapiens)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5juo
Q-score: 0.276
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Saccharomyces cerevisiae 80s ribosome bound to elongation factor eef2-gdp-sordarin and taura syndrome virus ires, structure i (3 MDa, Sample)
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 5jup
Q-score: 0.362
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae 80s ribosome bound to elongation factor eef2-gdp-sordarin and taura syndrome virus ires, structure ii (mid-rotated 40s subunit) (3 MDa, Sample)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5jus
Q-score: 0.21
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae 80s ribosome bound to elongation factor eef2-gdp-sordarin and taura syndrome virus ires, structure iii (mid-rotated 40s subunit) (3 MDa, Sample)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5jut
Q-score: 0.306
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae 80s ribosome bound to elongation factor eef2-gdp-sordarin and taura syndrome virus ires, structure iv (almost non-rotated 40s subunit) (3 MDa, Sample)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5juu
Q-score: 0.336
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Internal ribosome entry site (RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae 80s ribosome bound to elongation factor eef2-gdp-sordarin and taura syndrome virus ires, structure v (least rotated 40s subunit) (3 MDa, Sample)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5juo
Q-score: 0.204
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Saccharomyces cerevisiae 80s ribosome bound to tsv ires and eef2 translation initiation complex, structure i, map 2 (3 MDa, Sample)
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5jup
Q-score: 0.288
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae 80s ribosome bound to tsv ires and eef2 translation initiation complex, structure ii, map 2 (3 MDa, Sample)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5jus
Q-score: 0.179
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae 80s ribosome bound to tsv ires and eef2 translation initiation complex, structure iii, map 2 (3 MDa, Sample)
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
eLife (2016) 5 pp. e14874-e14874 [ DOI: doi:10.7554/eLife.14874 Pubmed: 27159452 ]
- Saccharomyces cerevisiae 80s ribosome bound to tsv ires and eef2 translation initiation complex, structure iii, map 3 (3 MDa, Sample)
- Internal ribosome entry site (80 kDa, RNA from Taura syndrome virus)
- Eukaryotic elongation factor 2 (94 kDa, Protein from Saccharomyces cerevisiae)
- Ribosome (3 MDa, Complex from Saccharomyces cerevisiae)