Structure of VRC44.01 Fab in complex with 3BNC117-purified C1080.c3 RnS SOSIP.664 HIV-1 Env trimer
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 9bio
Q-score: 0.547
Cale EM, Shen CH, Olia AS, Radakovich NA, Rawi R, Yang Y, Ambrozak DR, Bennici AK, Chuang GY, Crooks ED, Driscoll JI, Lin BC, Louder MK, Madden PJ, Messina MA, Osawa K, Stewart-Jones GBE, Verardi R, Vrakas Z, Xie D, Zhang B, Binley JM, Connors M, Koup RA, Pierson TC, Doria-Rose NA, Kwong PD, Mascola JR, Gorman J
Cell Rep (2024) 43 pp. 115010-115010 [ Pubmed: 39675002 DOI: doi:10.1016/j.celrep.2024.115010 ]
- Vrc44 and 3bnc117 fabs with repaired c1080 env trimer (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (19 kDa, Protein from Human immunodeficiency virus 1)
- Phosphate ion (94 Da, Ligand)
- Vrc44.01 heavy chain (13 kDa, Protein from Homo sapiens)
- 3bnc117 heavy chain (24 kDa, Protein from Homo sapiens)
- 3bnc117 light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vrc44.01 light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp160 (54 kDa, Protein from Human immunodeficiency virus 1)
Prefusion-stabilized Hendra virus fusion protein
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8dnr
Q-score: 0.606
Byrne PO, Blade EG, Fisher BE, Ambrozak DR, Ramamohan AR, Graham BS, Loomis RJ, McLellan JS
J Virol (2024) 98 pp. e0137223-e0137223 [ Pubmed: 38214525 DOI: doi:10.1128/jvi.01372-23 ]
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 4H3
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uop
Q-score: 0.58
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
Nat Commun (2023) 14 pp. 1494-1494 [ Pubmed: 36932063 DOI: doi:10.1038/s41467-023-36995-y ]
- Fusion glycoprotein f0 (52 kDa, Protein from Nipah henipavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 4h3 light chain (13 kDa, Protein from Mus musculus)
- Prefusion-stabilized nipah virus fusion protein complexed with fab 4h3 (Complex from Nipah henipavirus)
- Fab 4h3 heavy chain (15 kDa, Protein from Mus musculus)
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2D3
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7up9
Q-score: 0.592
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
Nat Commun (2023) 14 pp. 1494-1494 [ Pubmed: 36932063 DOI: doi:10.1038/s41467-023-36995-y ]
- Prefusion-stabilized nipah virus fusion protein complexed with fab 2d3 (Complex from Nipah henipavirus)
- Fab 2d3 heavy chain (14 kDa, Protein from Mus musculus)
- Fusion glycoprotein f0 (52 kDa, Protein from Nipah henipavirus)
- Fab 2d3 light chain (14 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H8
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7upa
Q-score: 0.612
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
Nat Commun (2023) 14 pp. 1494-1494 [ Pubmed: 36932063 DOI: doi:10.1038/s41467-023-36995-y ]
- Fusion glycoprotein f0 (52 kDa, Protein from Nipah henipavirus)
- Fab 1h8 heavy chain (15 kDa, Protein from Mus musculus)
- Prefusion-stabilized nipah virus fusion protein complexed with fab 1h8 (Complex from Nipah henipavirus)
- Fab 1h8 light chain (13 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2B12
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7upd
Q-score: 0.666
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
Nat Commun (2023) 14 pp. 1494-1494 [ Pubmed: 36932063 DOI: doi:10.1038/s41467-023-36995-y ]
- Fab 2b12 heavy chain (15 kDa, Protein from Mus musculus)
- Fab 2b12 light chain (14 kDa, Protein from Mus musculus)
- Prefusion-stabilized nipah virus fusion protein complexed with fab 2b12 (Complex from Nipah henipavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fusion glycoprotein f0 (52 kDa, Protein from Nipah henipavirus)
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1A9
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7upk
Q-score: 0.592
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
Nat Commun (2023) 14 pp. 1494-1494 [ Pubmed: 36932063 DOI: doi:10.1038/s41467-023-36995-y ]
- Prefusion-stabilized nipah virus fusion protein complexed with fab 1a9 (Complex from Nipah henipavirus)
- Fusion glycoprotein f0 (52 kDa, Protein from Nipah henipavirus)
- Fab 1a9 light chain (11 kDa, Protein from Mus musculus)
- Fab 1a9 heavy chain (12 kDa, Protein from Mus musculus)