Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7s0c
Q-score: 0.385
Tanaka S, Olson CA, Barnes CO, Higashide W, Gonzalez M, Taft J, Richardson A, Martin-Fernandez M, Bogunovic D, Gnanapragasam PNP, Bjorkman PJ, Spilman P, Niazi K, Rabizadeh S, Soon-Shiong P
Cell Rep (2022) 38 pp. 110348-110348 [ Pubmed: 35114110 DOI: doi:10.1016/j.celrep.2022.110348 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- N-612-017 light chain (23 kDa, Protein from Homo sapiens)
- Trimeric complex of sars-cov-2 spike glycoprotein bound to n-612-014 fab fragments (Complex from Homo sapiens)
- N-612-017 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-014
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7s0d
Q-score: 0.331
Tanaka S, Olson CA, Barnes CO, Higashide W, Gonzalez M, Taft J, Richardson A, Martin-Fernandez M, Bogunovic D, Gnanapragasam PNP, Bjorkman PJ, Spilman P, Niazi K, Rabizadeh S, Soon-Shiong P
Cell Rep (2022) 38 pp. 110348-110348 [ Pubmed: 35114110 DOI: doi:10.1016/j.celrep.2022.110348 ]
- N-612-014 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- N-612-014 light chain (23 kDa, Protein from Homo sapiens)
- Trimeric complex of sars-cov-2 spike glycoprotein bound to n-612-014 fab fragments (Complex from Homo sapiens)
Structure of the SARS-CoV-2 S1 subunit in complex with antibody N-612-004
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 7s0e
Q-score: 0.239
Tanaka S, Olson CA, Barnes CO, Higashide W, Gonzalez M, Taft J, Richardson A, Martin-Fernandez M, Bogunovic D, Gnanapragasam PNP, Bjorkman PJ, Spilman P, Niazi K, Rabizadeh S, Soon-Shiong P
Cell Rep (2022) 38 pp. 110348-110348 [ Pubmed: 35114110 DOI: doi:10.1016/j.celrep.2022.110348 ]
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- N-612-004 light chain (23 kDa, Protein from Homo sapiens)
- Trimeric complex of sars-cov-2 spike glycoprotein bound to n-612-014 fab fragments (Complex from Homo sapiens)
- N-612-004 fab heavy chain (24 kDa, Protein from Homo sapiens)
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 7rkv
Q-score: 0.3
Jette CA, Cohen AA, Gnanapragasam PNP, Muecksch F, Lee YE, Huey-Tubman KE, Schmidt F, Hatziioannou T, Bieniasz PD, Nussenzweig MC, West Jr AP, Keeffe JR, Bjorkman PJ, Barnes CO
Cell Rep (2021) 36 pp. 109760-109760 [ Pubmed: 34534459 DOI: doi:10.1016/j.celrep.2021.109760 ]
- C118 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Ternary complex of c118 fabs bound to the stabilized sars-cov-2 spike glycoprotein (720 kDa, Complex from Homo sapiens)
- C118 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 2)
Jette CA, Cohen AA, Gnanapragasam PNP, Muecksch F, Lee YE, Huey-Tubman KE, Schmidt F, Hatziioannou T, Bieniasz PD, Nussenzweig MC, West Jr AP, Keeffe JR, Bjorkman PJ, Barnes CO
Cell Rep (2021) 36 pp. 109760-109760 [ Pubmed: 34534459 DOI: doi:10.1016/j.celrep.2021.109760 ]