Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tcf
Q-score: 0.493
Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zuniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D
Nat Commun (2023) 14 pp. 5660-5660 [ DOI: doi:10.1038/s41467-023-41272-z Pubmed: 37704610 ]
- Integrin alpha-v heavy chain (48 kDa, Protein from Homo sapiens)
- Minibinder b8_bp_dslf (8 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ternary complex of integrin heterodimer (alpha-v beta-8) and the de novo minibinder protein b8_bp_dslf (Complex from Homo sapiens)
- Integrin beta-8 (40 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8tcg
Q-score: 0.422
Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zuniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D
Nat Commun (2023) 14 pp. 5660-5660 [ DOI: doi:10.1038/s41467-023-41272-z Pubmed: 37704610 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Integrin alpha-v heavy chain (47 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Minibinder b6_bp_dslf (8 kDa, Protein from synthetic construct)
- Integrin beta-6 (26 kDa, Protein from Homo sapiens)
- Ternary complex of integrin heterodimer (alpha-v beta-6) and the de novo minibinder protein b6_bp_dslf (Complex from Homo sapiens)
- Manganese (ii) ion (54 Da, Ligand)
Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D
Nat Commun (2021) 12 pp. 2294-2294 [ Pubmed: 33863889 DOI: doi:10.1038/s41467-021-22276-z ]
- D2_wm-01a (Protein from synthetic construct)
- D2_wm-01b (Protein from synthetic construct)
- D2_wm-01 (Complex from synthetic construct)
Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D
Nat Commun (2021) 12 pp. 2294-2294 [ Pubmed: 33863889 DOI: doi:10.1038/s41467-021-22276-z ]
- D2_wm-02 (Complex from synthetic construct)
- D2_wm-02b (Protein from synthetic construct)
- D2_wm-02a (Protein from synthetic construct)
Point Group nanocage T_Wm-1606
Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D
Nat Commun (2021) 12 pp. 2294-2294 [ Pubmed: 33863889 DOI: doi:10.1038/s41467-021-22276-z ]
- T_wm-1606 (Protein from synthetic construct)
- T_wm-1606 (Complex from synthetic construct)
Point Group nanocage I32_Wm-42
Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D
Nat Commun (2021) 12 pp. 2294-2294 [ Pubmed: 33863889 DOI: doi:10.1038/s41467-021-22276-z ]
- I32_wm-42b (Protein from synthetic construct)
- I32_wm-42a (Protein from synthetic construct)
- I32_wm-42 (Complex from synthetic construct)
CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6xss
Q-score: 0.305