CryoEM Structure of Computationally Designed Nanocage O32-ZL4
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8szz
Q-score: 0.591
Li Z, Wang S, Nattermann U, Bera AK, Borst AJ, Yaman MY, Bick MJ, Yang EC, Sheffler W, Lee B, Seifert S, Hura GL, Nguyen H, Kang A, Dalal R, Lubner JM, Hsia Y, Haddox H, Courbet A, Dowling Q, Miranda M, Favor A, Etemadi A, Edman NI, Yang W, Weidle C, Sankaran B, Negahdari B, Ross MB, Ginger DS, Baker D
Nat Mater (2023) 22 pp. 1556-1563 [ Pubmed: 37845322 DOI: doi:10.1038/s41563-023-01683-1 ]
- O32-zl4 component a (8 kDa, Protein from synthetic construct)
- O32-zl4 (764 kDa, Complex from Thermotoga maritima)
- O32-zl4 component b (23 kDa, Protein from Thermotoga maritima)
- Sodium ion (22 Da, Ligand)
Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tcf
Q-score: 0.493
Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zuniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D
Nat Commun (2023) 14 pp. 5660-5660 [ DOI: doi:10.1038/s41467-023-41272-z Pubmed: 37704610 ]
- Integrin beta-8 (40 kDa, Protein from Homo sapiens)
- Ternary complex of integrin heterodimer (alpha-v beta-8) and the de novo minibinder protein b8_bp_dslf (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Integrin alpha-v heavy chain (48 kDa, Protein from Homo sapiens)
- Minibinder b8_bp_dslf (8 kDa, Protein from synthetic construct)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8tcg
Q-score: 0.422
Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zuniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D
Nat Commun (2023) 14 pp. 5660-5660 [ DOI: doi:10.1038/s41467-023-41272-z Pubmed: 37704610 ]
- Manganese (ii) ion (54 Da, Ligand)
- Integrin beta-6 (26 kDa, Protein from Homo sapiens)
- Ternary complex of integrin heterodimer (alpha-v beta-6) and the de novo minibinder protein b6_bp_dslf (Complex from Homo sapiens)
- Integrin alpha-v heavy chain (47 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Minibinder b6_bp_dslf (8 kDa, Protein from synthetic construct)