Hepatitis B core protein with bound Geraniol
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8pwo
Q-score: 0.597
Khayenko V, Makbul C, Schulte C, Hemmelmann N, Bottcher B, Maric HM
To Be Published
- Capsid protein (21 kDa, Protein from Hepatitis B virus ayw/France/Tiollais/1979)
- Hepatitis b virus (5 MDa, Virus from Hepatitis B virus)
- Geraniol (154 Da, Ligand)
Hepatitis B core protein with bound SLLGRM-dimer
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8px6
Q-score: 0.592
Khayenko V, Makbul C, Schulte C, Hemmelmann N, Bottcher B, Maric HM
To Be Published
- Hepatitis b virus (5 MDa, Virus from Hepatitis B virus)
- External core antigen (21 kDa, Protein from Hepatitis B virus)
- Sllgrm-dimer (676 Da, Protein from synthetic construct)
ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8pjk
Q-score: 0.611
Ullrich A, Schneider J, Braz JM, Neu E, Staffen N, Stanek M, Blahova J, Hove T, Albert T, Allikalt A, Lober S, Bhardwaj K, Rodriguez-Rosado S, Fink E, Rasmussen T, Hubner H, Inoue A, Shoichet BK, Basbaum AJ, Bottcher B, Weikert D, Gmeiner P
bioRxiv (2023) [ DOI: doi:10.1101/2023.09.11.557127 ]
- Water (18 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- St171-bound serotonin 5-ht1a receptor - gi protein complex (Complex from Homo sapiens)
- (2r)-1-(heptadecanoyloxy)-3-{[(r)-hydroxy{[(1r,2r,3r,4r,5s,6r)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5z,8z,11z,14z)-icosa-5,8,11,14-tetraenoate (953 Da, Ligand)
- 6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{h}-1,4-benzoxazin-3-one (372 Da, Ligand)
- 5-hydroxytryptamine receptor 1a (51 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8pkm
Q-score: 0.468
Ullrich A, Schneider J, Braz JM, Neu E, Staffen N, Stanek M, Blahova J, Hove T, Albert T, Allikalt A, Lober S, Bhardwaj K, Rodriguez-Rosado S, Fink E, Rasmussen T, Hubner H, Inoue A, Shoichet BK, Basbaum AJ, Bottcher B, Weikert D, Gmeiner P
bioRxiv (2023) [ DOI: doi:10.1101/2023.09.11.557127 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- (2r)-1-(heptadecanoyloxy)-3-{[(r)-hydroxy{[(1r,2r,3r,4r,5s,6r)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5z,8z,11z,14z)-icosa-5,8,11,14-tetraenoate (953 Da, Ligand)
- (3-chloranyl-4-fluoranyl-phenyl)-[4-fluoranyl-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone (393 Da, Ligand)
- 5-hydroxytryptamine receptor 1a (51 kDa, Protein from Homo sapiens)
- Befiradol-bound serotonin 5-ht1a receptor - gi protein complex (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
HBc-F97L premature secretion phenotype
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7pz9
Q-score: 0.574
Makbul C, Kraft C, Griessmann M, Rasmussen T, Katzenberger K, Lappe M, Pfarr P, Stoffer C, Stohr M, Wandinger AM, Bottcher B
Viruses (2021) 13 [ DOI: doi:10.3390/v13112115 Pubmed: 34834922 ]
HBc-F97L (premature secretion phenotype) in complex with Triton X-100
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7pzi
Q-score: 0.601
Makbul C, Kraft C, Griessmann M, Rasmussen T, Katzenberger K, Lappe M, Pfarr P, Stoffer C, Stohr M, Wandinger AM, Bottcher B
Viruses (2021) 13 [ DOI: doi:10.3390/v13112115 Pubmed: 34834922 ]
HBc-F97L premature secretion phenotype
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7pzl
Q-score: 0.612
Makbul C, Kraft C, Griessmann M, Rasmussen T, Katzenberger K, Lappe M, Pfarr P, Stoffer C, Stohr M, Wandinger AM, Bottcher B
Viruses (2021) 13 [ DOI: doi:10.3390/v13112115 Pubmed: 34834922 ]
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7pzm
Q-score: 0.587
Makbul C, Kraft C, Griessmann M, Rasmussen T, Katzenberger K, Lappe M, Pfarr P, Stoffer C, Stohr M, Wandinger AM, Bottcher B
Viruses (2021) 13 [ DOI: doi:10.3390/v13112115 Pubmed: 34834922 ]
Mechanosensitive channel MscS solubilized with LMNG in open conformation
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 7onj
Q-score: 0.637
Flegler VJ, Rasmussen A, Borbil K, Boten L, Chen HA, Deinlein H, Halang J, Hellmanzik K, Loffler J, Schmidt V, Makbul C, Kraft C, Hedrich R, Rasmussen T, Bottcher B
PNAS (2021) 118 [ Pubmed: 34376558 DOI: doi:10.1073/pnas.2107095118 ]
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Water (18 Da, Ligand)
- Homoheptameric complex of mscs coordinated with lipids and detergents ddm and lmng (224 kDa, Complex from Escherichia coli)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Mechanosensitive channel of small conductance (mscs) (31 kDa, Protein from Escherichia coli)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Mechanosensitive channel MscS solubilized with LMNG in open conformation with added lipid
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7ooa
Q-score: 0.622
Flegler VJ, Rasmussen A, Borbil K, Boten L, Chen HA, Deinlein H, Halang J, Hellmanzik K, Loffler J, Schmidt V, Makbul C, Kraft C, Hedrich R, Rasmussen T, Bottcher B
PNAS (2021) 118 [ Pubmed: 34376558 DOI: doi:10.1073/pnas.2107095118 ]
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Mechanosensitive channel of small conductance (mscs) (31 kDa, Protein from Escherichia coli SE11)
- Homoheptameric complex of mscs coordinated with lipids and detergents ddm and lmng (224 kDa, Complex from Escherichia coli SE11)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)