Hepatitis B core protein with bound Geraniol
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8pwo
Q-score: 0.597
Khayenko V, Makbul C, Schulte C, Hemmelmann N, Bottcher B, Maric HM
To Be Published
- Capsid protein (21 kDa, Protein from Hepatitis B virus ayw/France/Tiollais/1979)
- Hepatitis b virus (5 MDa, Virus from Hepatitis B virus)
- Geraniol (154 Da, Ligand)
Hepatitis B core protein with bound SLLGRM-dimer
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8px6
Q-score: 0.592
Khayenko V, Makbul C, Schulte C, Hemmelmann N, Bottcher B, Maric HM
To Be Published
- Hepatitis b virus (5 MDa, Virus from Hepatitis B virus)
- External core antigen (21 kDa, Protein from Hepatitis B virus)
- Sllgrm-dimer (676 Da, Protein from synthetic construct)
Mechanosensitive channel MscS solubilized with LMNG in open conformation
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 7onj
Q-score: 0.637
Flegler VJ, Rasmussen A, Borbil K, Boten L, Chen HA, Deinlein H, Halang J, Hellmanzik K, Loffler J, Schmidt V, Makbul C, Kraft C, Hedrich R, Rasmussen T, Bottcher B
PNAS (2021) 118 [ Pubmed: 34376558 DOI: doi:10.1073/pnas.2107095118 ]
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Water (18 Da, Ligand)
- Homoheptameric complex of mscs coordinated with lipids and detergents ddm and lmng (224 kDa, Complex from Escherichia coli)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Mechanosensitive channel of small conductance (mscs) (31 kDa, Protein from Escherichia coli)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Mechanosensitive channel MscS solubilized with LMNG in open conformation with added lipid
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7ooa
Q-score: 0.622
Flegler VJ, Rasmussen A, Borbil K, Boten L, Chen HA, Deinlein H, Halang J, Hellmanzik K, Loffler J, Schmidt V, Makbul C, Kraft C, Hedrich R, Rasmussen T, Bottcher B
PNAS (2021) 118 [ Pubmed: 34376558 DOI: doi:10.1073/pnas.2107095118 ]
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Mechanosensitive channel of small conductance (mscs) (31 kDa, Protein from Escherichia coli SE11)
- Homoheptameric complex of mscs coordinated with lipids and detergents ddm and lmng (224 kDa, Complex from Escherichia coli SE11)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7od4
Q-score: 0.557
Makbul C, Khayenko V, Maric HM, Bottcher B
Microorganisms (2021) 9 [ DOI: doi:10.3390/microorganisms9050956 Pubmed: 33946808 ]
- External core antigen (21 kDa, Protein from Hepatitis B virus)
- Hepatitis b virus (4 MDa, Virus from Hepatitis B virus)
Hepatitis B core protein + SLLGRM
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7od7
Q-score: 0.569
Makbul C, Khayenko V, Maric HM, Bottcher B
Microorganisms (2021) 9 [ DOI: doi:10.3390/microorganisms9050956 Pubmed: 33946808 ]
- Capsid protein (21 kDa, Protein from Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979))
- Hepatitis b virus (4 MDa, Virus from Hepatitis B virus)
- Sllrgm (1 kDa, Protein from synthetic construct)
Hepatitis B core protein capsid, mutant F97L with bound MHRSLLGRMKGA
Makbul C, Khayenko V, Maric HM, Bottcher B
Microorganisms (2021) 9 [ DOI: doi:10.3390/microorganisms9050956 Pubmed: 33946808 ]
- Peptide mhrsllgrmkga (Protein from synthetic construct)
- Hepatitis b core protein (Protein from Hepatitis B virus)
- Hepatitis b virus (4 MDa, Virus from Hepatitis B virus)
STRUCTURE OF THE MECHANOSENSITIVE CHANNEL MSCS EMBEDDED IN THE MEMBRANE BILAYER
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6rld
Q-score: 0.516
Rasmussen T, Flegler VJ, Rasmussen A, Bottcher B
J Mol Biol (2019) 431 pp. 3081-3090 [ Pubmed: 31291591 DOI: doi:10.1016/j.jmb.2019.07.006 ]
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6i5a
Q-score: 0.679
Song B, Lenhart J, Flegler VJ, Makbul C, Rasmussen T, Bottcher B
Ultramicroscopy (2019) 203 pp. 145-154 [ DOI: doi:10.1016/j.ultramic.2019.01.002 Pubmed: 30738626 ]
- Tobacco mosaic virus (40 MDa, Virus from Tobacco mosaic virus)
- Capsid protein (17 kDa, Protein from Tobacco mosaic virus (strain vulgare))
beta-galactosidase (integrating mode)
Song B, Lenhart J, Flegler VJ, Makbul C, Rasmussen T, Bottcher B
Ultramicroscopy (2019) 203 pp. 145-154 [ DOI: doi:10.1016/j.ultramic.2019.01.002 Pubmed: 30738626 ]
- Beta-galactosidase (Protein)
- Beta-galactosidase (465 kDa, Complex from Escherichia coli)