Nipah virus (NiV) fusion protein in complex with neutralizing Fab92
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8rvn
Q-score: 0.528
Avanzato VA, Bushmaker T, Oguntuyo KY, Yinda CK, Duyvesteyn HME, Stass R, Meade-White K, Rosenke R, Thomas T, van Doremalen N, Saturday G, Doores KJ, Lee B, Bowden TA, Munster VJ
J Virol (2024) 98 pp. e0063824-e0063824 [ Pubmed: 39240113 DOI: doi:10.1128/jvi.00638-24 ]
- Nipah virus fusion (f) glycoprotein in complex with fab92 (Complex from Henipavirus nipahense)
- Fab92 light chain (22 kDa, Protein from Oryctolagus cuniculus)
- Fab92 heavy chain (22 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fusion glycoprotein f0 (55 kDa, Protein from Henipavirus nipahense)
Recombinant Mayaro virus-like particle
Kim YC, Watanabe Y, Arlen-Celina L, Song X, de Oliveira Souza R, Stass R, Azar SR, Rossi SL, Claser C, Kummerer BM, Crispin M, Bowden TA, Huiskonen JT, Reyes-Sandoval A
NPJ Vaccines (2024) 9 pp. 243-243 [ Pubmed: 39690153 DOI: doi:10.1038/s41541-024-01021-9 ]
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=4 VLP)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7zq8
Q-score: 0.612
Kingston NJ, Grehan K, Snowden JS, Hassall M, Alzahrani J, Paesen GC, Sherry L, Hayward C, Roe A, Stephen S, Tomlinson D, Zeltina A, Doores KJ, Ranson NA, Stacey M, Page M, Rose NJ, Bowden TA, Rowlands DJ, Stonehouse NJ
mSphere (2023) 8 pp. e0056822-e0056822 [ Pubmed: 36719225 DOI: doi:10.1128/msphere.00568-22 ]
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=3* VLP)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7zqa
Q-score: 0.513
Kingston NJ, Grehan K, Snowden JS, Hassall M, Alzahrani J, Paesen GC, Sherry L, Hayward C, Roe A, Stephen S, Tomlinson D, Zeltina A, Doores KJ, Ranson NA, Stacey M, Page M, Rose NJ, Bowden TA, Rowlands DJ, Stonehouse NJ
mSphere (2023) 8 pp. e0056822-e0056822 [ Pubmed: 36719225 DOI: doi:10.1128/msphere.00568-22 ]
Rabies virus glycoprotein in complex with Fab fragments of 17C7 and 1112-1 neutralizing antibodies
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8a1e
Q-score: 0.539
Ng WM, Fedosyuk S, English S, Augusto G, Berg A, Thorley L, Haselon AS, Segireddy RR, Bowden TA, Douglas AD
Cell Host Microbe (2022) 30 pp. 1219-1230.e7 [ Pubmed: 35985336 DOI: doi:10.1016/j.chom.2022.07.014 ]
- Glycoprotein (56 kDa, Protein from Rabies virus strain Pasteur vaccin)
- Fab 17c7 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Fab 1112-1 heavy chain variable domain (13 kDa, Protein from Mus musculus)
- Fab 17c7 light chain variable domain (11 kDa, Protein from Homo sapiens)
- Rabies virus glycoprotein (chain a) in complex with fab 1112-1 (chains b and c) and fab 17c7 (chains d and e) (330 kDa, Complex from Rabies lyssavirus)
- Fab 1112-1 light chain variable domain (11 kDa, Protein from Mus musculus)
Hantaan virus-like particle glycoprotein lattice.
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ
Mbio (2021) 12 pp. e0253120-e0253120 [ DOI: doi:10.1128/mBio.02531-20 Pubmed: 34225492 ]
Hantaan virus-like particle glycoprotein spike in complex with Fab fragment HTN-Gn1.
Resolution: 19.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7nrh
Q-score: 0.052
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ
Mbio (2021) 12 pp. e0253120-e0253120 [ DOI: doi:10.1128/mBio.02531-20 Pubmed: 34225492 ]
- Fab fragment htn-gn1 light chain (22 kDa, Protein from Oryctolagus cuniculus)
- Envelope polyprotein (40 kDa, Protein from Hantaan orthohantavirus)
- Hantaan orthohantavirus (Virus from Hantaan orthohantavirus)
- Fab fragment htn-gn1 heavy chain (24 kDa, Protein from Oryctolagus cuniculus)
Puumala virus-like particle glycoprotein spike in complex with fab fragment P-4G2.
Resolution: 13.4 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7b09
Q-score: 0.077
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ DOI: doi:10.7554/eLife.58242 Pubmed: 33349334 ]
- Heavy chain of fab fragment p-4g2 (25 kDa, Protein from Myodes glareolus)
- Envelope polyprotein (40 kDa, Protein from Puumala orthohantavirus)
- Envelope polyprotein (49 kDa, Protein from Puumala orthohantavirus)
- Puumala virus - sotkamo (Virus from Puumala virus - Sotkamo)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of fab fragment p-4g2 (23 kDa, Protein from Myodes glareolus)
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ DOI: doi:10.7554/eLife.58242 Pubmed: 33349334 ]
Puumala virus-like particle glycoprotein lattice.
Resolution: 13.9 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7b0a
Q-score: 0.066
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ DOI: doi:10.7554/eLife.58242 Pubmed: 33349334 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Puumala orthohantavirus (Virus from Puumala orthohantavirus)
- Envelope polyprotein (40 kDa, Protein from Puumala orthohantavirus)
- Envelope polyprotein (49 kDa, Protein from Puumala orthohantavirus)