Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8ur5
Q-score: 0.429
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Hutchinson GB, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP
Cell Rep (2023) 42 pp. 113552-113552 [ Pubmed: 38096058 DOI: doi:10.1016/j.celrep.2023.113552 ]
- I53_dn5 nanoparticle displaying the trimeric ha heads with heptad domain, th-1heptad-i53_dn5 (local refinement of th-1heptad) (Complex)
- Trimer head ha (Complex from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Trimer head ha,hemagglutinin ha1 chain (44 kDa, Protein from synthetic construct)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ur7
Q-score: 0.403
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Hutchinson GB, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP
Cell Rep (2023) 42 pp. 113552-113552 [ Pubmed: 38096058 DOI: doi:10.1016/j.celrep.2023.113552 ]
- I53_dn5 nanoparticle displaying the trimeric ha heads with heptad domain, th-6heptad-i53_dn5 (Complex)
- Trimer head ha,hemagglutinin ha1 chain (48 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pentamer (Complex from synthetic construct)
- Trimer head ha (Complex from synthetic construct)
Resolution: 3.85 Å
EM Method: Single-particle
Fitted PDBs: 6xsk
Q-score: 0.406
Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M
Immunity (2022) 55 pp. 2405-2418.e7 [ DOI: doi:10.1016/j.immuni.2022.10.015 Pubmed: 36356572 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 789-203-3c12 fab heavy and light chains (Cellular component from Macaca mulatta)
- Influenza hemagglutinin (Cellular component from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- 789-203-3c12 fab heavy chain (49 kDa, Protein from Macaca mulatta)
- 789-203-3c12 fab light chain (23 kDa, Protein from Macaca mulatta)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Influenza hemagglutinin si06 trimer in complex with 789-203-3c12 fab (Cellular component)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7kna
Q-score: 0.499
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ Pubmed: 33762730 DOI: doi:10.1038/s41586-021-03365-x ]