Deconvolved phiPA3 PhuN Tetramer, p2
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8fne
Q-score: 0.267
Nieweglowska ES, Brilot AF, Mendez-Moran M, Kokontis C, Baek M, Li J, Cheng Y, Baker D, Bondy-Denomy J, Agard DA
Nat Commun (2023) 14 pp. 927-927 [ Pubmed: 36807264 DOI: doi:10.1038/s41467-023-36526-9 ]
Tracing p2 phiPA3 PhuN Tetramer Interfaces
Nieweglowska ES, Brilot AF, Mendez-Moran M, Kokontis C, Baek M, Li J, Cheng Y, Baker D, Bondy-Denomy J, Agard DA
Nat Commun (2023) 14 pp. 927-927 [ Pubmed: 36807264 DOI: doi:10.1038/s41467-023-36526-9 ]
Nieweglowska ES, Brilot AF, Mendez-Moran M, Kokontis C, Baek M, Li J, Cheng Y, Baker D, Bondy-Denomy J, Agard DA
Nat Commun (2023) 14 pp. 927-927 [ Pubmed: 36807264 DOI: doi:10.1038/s41467-023-36526-9 ]
SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8dv1
Q-score: 0.415
Remesh SG, Merz GE, Brilot AF, Chio US, Rizo AN, Pospiech Jr TH, Lui I, Laurie MT, Glasgow J, Le CQ, Zhang Y, Diwanji D, Hernandez E, Lopez J, Mehmood H, Pawar KI, Pourmal S, Smith AM, Zhou F, DeRisi J, Kortemme T, Rosenberg OS, Glasgow A, Leung KK, Wells JA, Verba KA
Structure (2023) 31 pp. 253- [ DOI: doi:10.1016/j.str.2023.01.009 Pubmed: 36805129 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2,immunoglobulin gamma-1 heavy chain fusion,immunoglobulin gamma-1 heavy chain (110 kDa, Protein from Homo sapiens)
- Angiotensin-converting enzyme 2,immunoglobulin gamma-1 heavy chain fusion (Complex from Homo sapiens)
- Sars-cov-2 wuhan-hu-1-spike bound to linker variant of affinity matured ace2 mimetic cvd432 (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8dv2
Q-score: 0.394
Remesh SG, Merz GE, Brilot AF, Chio US, Rizo AN, Pospiech Jr TH, Lui I, Laurie MT, Glasgow J, Le CQ, Zhang Y, Diwanji D, Hernandez E, Lopez J, Mehmood H, Pawar KI, Pourmal S, Smith AM, Zhou F, DeRisi J, Kortemme T, Rosenberg OS, Glasgow A, Leung KK, Wells JA, Verba KA
Structure (2023) 31 pp. 253- [ DOI: doi:10.1016/j.str.2023.01.009 Pubmed: 36805129 ]
- Spike glycoprotein (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2,immunoglobulin gamma-1 heavy chain fusion (113 kDa, Protein from Homo sapiens)
- Sars-cov-2 wuhan-hu-1-spike bound to linker variant of affinity matured ace2 mimetic cvd293 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2,immunoglobulin gamma-1 heavy chain fusion (Complex)
Engineered disulfide cross-linked closed conformation of the Yeast gamma-TuRC(SS)
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7m2w
Q-score: 0.435
Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA
eLife (2021) 10 [ DOI: doi:10.7554/eLife.65168 Pubmed: 33949948 ]
- Spindle pole body component spc98 (98 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Engineered disulfide cross-linked closed conformation of the yeast gamma-turc(ss) (Complex from Saccharomyces cerevisiae)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin gamma chain (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Spindle pole body component spc97 (96 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Spindle pole body component 110 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Open conformation of the Yeast wild-type gamma-TuRC
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 7m2x
Q-score: 0.295
Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA
eLife (2021) 10 [ DOI: doi:10.7554/eLife.65168 Pubmed: 33949948 ]
- Spindle pole body component spc98 (98 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Tubulin gamma chain (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Open conformation of the yeast wild-type gamma-turc (Complex from Saccharomyces cerevisiae)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Spindle pole body component 110 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Spindle pole body component spc97 (96 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Closed conformation of the Yeast wild-type gamma-TuRC
Resolution: 4.03 Å
EM Method: Helical reconstruction
Fitted PDBs: 7m2y
Q-score: 0.249
Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA
eLife (2021) 10 [ DOI: doi:10.7554/eLife.65168 Pubmed: 33949948 ]
- Spindle pole body component spc98 (98 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Tubulin gamma chain (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Spindle pole body component 110 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Spindle pole body component spc97 (96 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Closed conformation of the yeast wild-type gamma-turc (Complex from Saccharomyces cerevisiae)
Monomeric single-particle reconstruction of the Yeast gamma-TuSC
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7m2z
Q-score: 0.314
Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA
eLife (2021) 10 [ DOI: doi:10.7554/eLife.65168 Pubmed: 33949948 ]
- Spindle pole body component spc98 (98 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Tubulin gamma chain (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Monomer of the yeast gamma-tusc (300 kDa, Complex from Saccharomyces cerevisiae)
- Spindle pole body component spc97 (96 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Single-particle reconstruction of a dimer of the Yeast gamma-TuSC
Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA
eLife (2021) 10 [ DOI: doi:10.7554/eLife.65168 Pubmed: 33949948 ]