Cryo-EM structure of full-length human immunoglobulin M
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 [ DOI: 10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
Image sets:
Cryo-EM structure of full-length human immunoglobulin M
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Human igm heavy chain (Protein from Homo sapiens)
- Full-length human igm pentamer (Complex from Homo sapiens)
- J chain (Protein from Homo sapiens)
- Human igm light chain (Protein from Homo sapiens)
Cryo-EM structure of human monomeric IgM-Fc
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7qdo
Q-score: 0.364
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Human monomeric igm-fc (Complex from Homo sapiens)
- Isoform 2 of immunoglobulin heavy constant mu (47 kDa, Protein from Homo sapiens)
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 1
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 8ady
Q-score: 0.122
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Full-length human igm pentamer (Complex from Homo sapiens)
- Igm c2-domain from mouse (12 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
- Igm fab, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
- Igm fab, heavy chain (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2
Resolution: 6.7 Å
EM Method: Single-particle
Fitted PDBs: 8adz
Q-score: 0.104
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Full-length human igm pentamer (Complex from Homo sapiens)
- Igm c2-domain from mouse (12 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
- Igm fab, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
- Igm fab, heavy chain (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 3
Resolution: 7.1 Å
EM Method: Single-particle
Fitted PDBs: 8ae0
Q-score: 0.104
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Full-length human igm pentamer (Complex from Homo sapiens)
- Igm c2-domain from mouse (12 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
- Igm fab, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
- Igm fab, heavy chain (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 5
Resolution: 8.5 Å
EM Method: Single-particle
Fitted PDBs: 8ae2
Q-score: 0.096
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Full-length human igm pentamer (Complex from Homo sapiens)
- Igm c2-domain from mouse (12 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
- Igm fab, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
- Igm fab, heavy chain (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 4
Resolution: 6.8 Å
EM Method: Single-particle
Fitted PDBs: 8ae3
Q-score: 0.115
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ DOI: doi:10.1038/s41467-022-34090-2 Pubmed: 36274064 ]
- Full-length human igm pentamer (Complex from Homo sapiens)
- Igm c2-domain from mouse (12 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
- Igm fab, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
- Igm fab, heavy chain (24 kDa, Protein from Homo sapiens)
Structure of Coronavirus Spike from Smuggled Guangdong Pangolin
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7bbh
Q-score: 0.568
Wrobel AG, Benton DJ, Xu P, Calder LJ, Borg A, Roustan C, Martin SR, Rosenthal PB, Skehel JJ, Gamblin SJ
Nat Commun (2021) 12 pp. 837-837 [ DOI: doi:10.1038/s41467-021-21006-9 Pubmed: 33547281 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Surface glycoprotein (138 kDa, Protein from Pangolin coronavirus)
- Pangolin coronavirus spike ectodomain trimer (410 kDa, Complex from Pangolin coronavirus)