Western Equine Encephalitis Virus-Like Particle in Complex with SKW19 Fab
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
Western Equine Encephalitis Virus-Like Particle in Complex with SKW24 Fab
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
Eastern Equine Encephalitis Virus-Like Particle in Complex with SKE26 Fab
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8dwo
Q-score: 0.483
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Ske26 fab light chain (23 kDa, Protein from Macaca fascicularis)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Envelope glycoprotein e1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Envelope glycoprotein e2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Ske26 fab heavy chain (25 kDa, Protein from Macaca fascicularis)
Cryo-EM Structure of Western Equine Encephalitis Virus
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 8dec
Q-score: 0.152
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
- Capsid protein (29 kDa, Protein from Western equine encephalitis virus)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW19 fab
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8ded
Q-score: 0.363
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skw19 fab light chain (23 kDa, Protein from Homo sapiens)
- Skw19 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
Asymmetric Unit of Western Equine Encephalitis Virus
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8dee
Q-score: 0.459
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
- Capsid protein (29 kDa, Protein from Western equine encephalitis virus)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW24 fab
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8def
Q-score: 0.302
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skw24 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Skw24 fab light chain (22 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)