Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 7ukl
Q-score: 0.49
Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD
Immunity (2023) 56 pp. 2442- [ DOI: doi:10.1016/j.immuni.2023.09.003 Pubmed: 37776849 ]
- 12-16 fab light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Antibody 12-16 in complex with prefusion sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 12-16 fab heavy chain (14 kDa, Protein from Homo sapiens)
Cryo-EM structure of Antibody 12-19 in complex with prefusion SARS-CoV-2 Spike glycoprotein
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7ukm
Q-score: 0.498
To Be Published
- 12-19 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody 12-19 in complex with prefusion sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 12-19 fab light chain (12 kDa, Protein from Homo sapiens)
Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8dwo
Q-score: 0.483
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Ske26 fab light chain (23 kDa, Protein from Macaca fascicularis)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Envelope glycoprotein e1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Envelope glycoprotein e2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Ske26 fab heavy chain (25 kDa, Protein from Macaca fascicularis)
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05, local refinement
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8eeu
Q-score: 0.462
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Complex between venezuelan equine encephalitis virus-like particle and fab skt05 (33 MDa, Complex from Venezuelan equine encephalitis virus)
- Fab skt05 light chain (23 kDa, Protein from Macaca fascicularis)
- Coat protein (138 kDa, Protein from Venezuelan equine encephalitis virus)
- Fab skt05 heavy chain (25 kDa, Protein from Macaca fascicularis)
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20, local refinement
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8eev
Q-score: 0.44
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Fab skt20 light chain (23 kDa, Protein from Macaca fascicularis)
- Fab skt20 heavy chain (25 kDa, Protein from Macaca fascicularis)
- Complex between venezuelan equine encephalitis virus-like particle and fab skt20 (33 MDa, Complex from Venezuelan equine encephalitis virus)
- Coat protein (138 kDa, Protein from Venezuelan equine encephalitis virus)
Cryo-EM Structure of Western Equine Encephalitis Virus
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 8dec
Q-score: 0.152
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
- Capsid protein (29 kDa, Protein from Western equine encephalitis virus)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW19 fab
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8ded
Q-score: 0.363
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skw19 fab light chain (23 kDa, Protein from Homo sapiens)
- Skw19 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
Asymmetric Unit of Western Equine Encephalitis Virus
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8dee
Q-score: 0.459
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
- Capsid protein (29 kDa, Protein from Western equine encephalitis virus)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW24 fab
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8def
Q-score: 0.302
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skw24 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Skw24 fab light chain (22 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 8dul
Q-score: 0.241
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Spike glycoprotein e1 (52 kDa, Protein from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein e2 (45 kDa, Protein from Western equine encephalitis virus)
- Antibody fab skt05 heavy chain (25 kDa, Protein from Macaca fascicularis)
- Western equine encephalitis virus trimer in complex with antibody fab skt05 (Complex from Western equine encephalitis virus)
- Antibody fab skt05 light chain (23 kDa, Protein from Macaca fascicularis)