Full-length structure of the substrate-free tyrosine hydroxylase (apo-TH).
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7a2g
Q-score: 0.234
Bueno-Carrasco MT, Cuellar J, Flydal MI, Santiago C, Krakenes TA, Kleppe R, Lopez-Blanco JR, Marcilla M, Teigen K, Alvira S, Chacon P, Martinez A, Valpuesta JM
Nat Commun (2022) 13 pp. 74-74 [ DOI: doi:10.1038/s41467-021-27657-y Pubmed: 35013193 ]
- Water (18 Da, Ligand)
- Fe (iii) ion (55 Da, Ligand)
- Tyrosine hydroxylase (Complex from Homo sapiens)
- Tyrosine 3-monooxygenase (47 kDa, Protein from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6zvp
Q-score: 0.22
Bueno-Carrasco MT, Cuellar J, Flydal MI, Santiago C, Krakenes TA, Kleppe R, Lopez-Blanco JR, Marcilla M, Teigen K, Alvira S, Chacon P, Martinez A, Valpuesta JM
Nat Commun (2022) 13 pp. 74-74 [ DOI: doi:10.1038/s41467-021-27657-y Pubmed: 35013193 ]
- L-dopamine (153 Da, Ligand)
- Fe (iii) ion (55 Da, Ligand)
- Tyrosine 3-monooxygenase (51 kDa, Protein from Homo sapiens)
- Tyrosine hydroxylase in complex with dopamine (Complex from Homo sapiens)
SARS-CoV-2 spike in prefusion state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6zow
Q-score: 0.451
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]
- Water (18 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Spike homotrimer in prefusion state (Complex from Severe acute respiratory syndrome coronavirus 2)
- Dimethyl sulfoxide (78 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6zp5
Q-score: 0.417
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in prefusion state (flexibility analysis, 1-up closed conformation) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Dimethyl sulfoxide (78 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6zp7
Q-score: 0.368
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]
- Sars-cov-2 spike in prefusion state (flexibility analysis, 1-up open conformation) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Dimethyl sulfoxide (78 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 6b5b
Q-score: 0.188
Tenthorey JL, Haloupek N, Lopez-Blanco JR, Grob P, Adamson E, Hartenian E, Lind NA, Bourgeois NM, Chacon P, Nogales E, Vance RE
Science (2017) 358 pp. 888-893 [ Pubmed: 29146805 DOI: doi:10.1126/science.aao1140 ]
- Nlrc4 (Complex from Mus musculus)
- Flagellin (58 kDa, Protein from Legionella pneumophila)
- Nlr family card domain-containing protein 4 (116 kDa, Protein from Mus musculus)
- Naip5-nlrc4-flagellin inflammasome (Complex)
- Baculoviral iap repeat-containing protein 1e (159 kDa, Protein from Mus musculus)
- Naip5 (Complex from Mus musculus)
- Flagellin (Complex from Legionella pneumophila)
Near-atomic cryo-EM structure of PRC1 bound to the microtubule
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 5kmg
Q-score: 0.41
Kellogg EH, Howes S, Ti SC, Ramirez-Aportela E, Kapoor TM, Chacon P, Nogales E
PNAS (2016) 113 pp. 9430-9439 [ Pubmed: 27493215 DOI: doi:10.1073/pnas.1609903113 ]
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Protein regulator of cytokinesis 1 (15 kDa, Protein from Homo sapiens)
- Tubulin beta chain (48 kDa, Protein from Sus scrofa)
- Peloruside a (548 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha-1b chain (49 kDa, Protein from Sus scrofa)
- Ternary complex of prc1 fragment (prc1-sc), alpha-tubulin, and beta-tubulin. (Complex)