The structure of the core of the pyruvate dehydrogenase complex in the mitochondria of pig hearts.
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9j1w
Q-score: 0.543
The map of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2
The conformation of lipoy domain binding the core of the pyruvate dehydrogenase complex.
Cryo-EM structure of the DHA bound FFA1-Gi complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9k1c
Q-score: 0.462
Ke Y, Huang Y, Yi C, Ma L, Chu X, Wu B, Zhao Q, Han S
Cell Rep (2024) 43 pp. 115024-115024 [ DOI: doi:10.1016/j.celrep.2024.115024 Pubmed: 39616615 ]
- Free fatty acid receptor 1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Dha bound ffa1-gi complex (Complex from Homo sapiens)
- Docosa-4,7,10,13,16,19-hexaenoic acid (328 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Cryo-EM structure of the butyrate bound FFA2-Gi complex
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 9k1d
Q-score: 0.478
Ke Y, Huang Y, Yi C, Ma L, Chu X, Wu B, Zhao Q, Han S
Cell Rep (2024) 43 pp. 115024-115024 [ DOI: doi:10.1016/j.celrep.2024.115024 Pubmed: 39616615 ]
- Butanoic acid (88 Da, Ligand)
- Cryo-em structure of the butyrate bound ffa2-gi complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Free fatty acid receptor 2 (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Cryo-EM structure of the glucagon receptor bound to beta-arrestin 1 in ligand-free state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8jru
Q-score: 0.438
Chen K, Zhang C, Lin S, Yan X, Cai H, Yi C, Ma L, Chu X, Liu Y, Zhu Y, Han S, Zhao Q, Wu B
Nature (2023) 620 pp. 904-910 [ DOI: doi:10.1038/s41586-023-06420-x Pubmed: 37558880 ]
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Nanobody 32 (13 kDa, Protein from Escherichia phage EcSzw-2)
- The glucagon receptor bound to beta-arrestin 1 (Complex from Homo sapiens)
- Ha signal peptide,hpc4 purification tag,glucagon receptor,c-terminal tail of vasopressin v2 receptor (54 kDa, Protein from Homo sapiens)
- Beta-arrestin 1 and single-chain fragment variable 30 (scfv30) (69 kDa, Protein from Bos taurus)