Cryo-EM structure of the purinergic receptor P2Y1R in complex with 2MeSADP and G11
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xxh
Q-score: 0.443
Li B, Han S, Wang M, Yu Y, Ma L, Chu X, Tan Q, Zhao Q, Wu B
Protein Cell (2023) 14 pp. 382-386 [ DOI: doi:10.1093/procel/pwac025 Pubmed: 37155313 ]
- Guanine nucleotide-binding protein g(11) subunit alpha (41 kDa, Protein from Homo sapiens)
- P2y purinoceptor 1 (46 kDa, Protein from Homo sapiens)
- The purinergic receptor p2y1r in complex with 2mesadp, g11 and scfv16 (10 MDa, Complex from Homo sapiens)
- 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate) (473 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7xxi
Q-score: 0.445
Li B, Han S, Wang M, Yu Y, Ma L, Chu X, Tan Q, Zhao Q, Wu B
Protein Cell (2023) 14 pp. 382-386 [ DOI: doi:10.1093/procel/pwac025 Pubmed: 37155313 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-2 (40 kDa, Protein from Homo sapiens)
- 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate) (473 Da, Ligand)
- The purinergic receptor p2y12r in complex with 2mesadp and gi (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- P2y purinoceptor 12 (43 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8heb
Q-score: 0.379
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- 9h1 fab (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hec
Q-score: 0.358
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8hed
Q-score: 0.469
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Sars-cov-2 spike glycoprotein rbd (Complex from Oryctolagus cuniculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 wt spike glycoprotein rbd complex with 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- 9h1 fab (Complex)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8gzz
Q-score: 0.491
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- 1h1 fab (Complex)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8h00
Q-score: 0.484
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8h01
Q-score: 0.342
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
cryo-EM density map of SARS-CoV-2 Omicron BA.1 spike in complex with RmAb 1H1 IgG
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 8itu
Q-score: 0.263
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Sars-cov-2 omicron ba.1 spike glycoprotein complex with 1h1 igg (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.1 spike glycoprotein (Protein)
- Omicron ba.1 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 igg (Complex)
