sub-tomogram averaging results of tetrameric 5-HT3A receptor on cell-derived vesicles
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ Pubmed: 39232129 DOI: doi:10.1038/s44318-024-00191-5 ]
Sub-tomogram averaging results of pentameric 5-HT3A receptor on cell-derived vesicles
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ Pubmed: 39232129 DOI: doi:10.1038/s44318-024-00191-5 ]
Tetrameric 5-HT3A receptor in Salipro (apo, asymmetric)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8c1w
Q-score: 0.366
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ Pubmed: 39232129 DOI: doi:10.1038/s44318-024-00191-5 ]
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
- Tetrameric 5-ht3ar receptor in salipro (apo, asymmetric) (220 kDa, Complex from Mus musculus)
Tetrameric 5-HT3aR in Salipro (apo state, symmetric)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8c1z
Q-score: 0.399
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ Pubmed: 39232129 DOI: doi:10.1038/s44318-024-00191-5 ]
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
- Tetrameric 5-ht3a receptor in salipro (apo, symmetric) (220 kDa, Complex from Mus musculus)
Tetrameric 5-HT3aR in Salipro (holo state, symmetric)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8c20
Q-score: 0.376
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ Pubmed: 39232129 DOI: doi:10.1038/s44318-024-00191-5 ]
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
- Tetrameric 5-ht3a receptor in salipro (holo, symmetric) (220 kDa, Complex from Mus musculus)
- Serotonin (176 Da, Ligand)
Tetrameric 5-HT3A receptor in Salipro (holo, asymmetric)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8c21
Q-score: 0.406
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ Pubmed: 39232129 DOI: doi:10.1038/s44318-024-00191-5 ]
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
- Tetrameric 5-ht3ar receptor in salipro (holo, asymmetric) (220 kDa, Complex from Mus musculus)
- Serotonin (176 Da, Ligand)
Structural insights into the activation mechanism of antimicrobial GBP1: Polymeric assembly of GBP1
Weismehl M, Chu X, Kutsch M, Lauterjung P, Herrmann C, Kudryashev M, Daumke O
EMBO J (2024) 43 pp. 615-636 [ DOI: doi:10.1038/s44318-023-00023-y Pubmed: 38267655 ]
Resolution: 26.8 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8r1a
Q-score: 0.03
Weismehl M, Chu X, Kutsch M, Lauterjung P, Herrmann C, Kudryashev M, Daumke O
EMBO J (2024) 43 pp. 615-636 [ DOI: doi:10.1038/s44318-023-00023-y Pubmed: 38267655 ]
- Aluminum fluoride (83 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Membrane-bound oligomer of human guanylate-binding protein 1 (gbp1) (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Guanylate binding protein 1 (69 kDa, Protein from Homo sapiens)
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode I)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8jcu
Q-score: 0.401
Wang X, Wang M, Xu T, Feng Y, Shao Q, Han S, Chu X, Xu Y, Lin S, Zhao Q, Wu B
Cell Res (2023) 33 pp. 762-774 [ Pubmed: 37286794 DOI: doi:10.1038/s41422-023-00830-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Metabotropic glutamate receptor 3,serine/threonine-protein kinase mtor (112 kDa, Protein from Homo sapiens)
- Metabotropic glutamate receptor 2,peptidyl-prolyl cis-trans isomerase fkbp1a (109 kDa, Protein from Homo sapiens)
- Mglu2-3 heterodimer in presence of ly341495 (Complex from Homo sapiens)
- 2-[(1s,2s)-2-carboxycyclopropyl]-3-(9h-xanthen-9-yl)-d-alanine (353 Da, Ligand)
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode II)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8jcv
Q-score: 0.344
Wang X, Wang M, Xu T, Feng Y, Shao Q, Han S, Chu X, Xu Y, Lin S, Zhao Q, Wu B
Cell Res (2023) 33 pp. 762-774 [ Pubmed: 37286794 DOI: doi:10.1038/s41422-023-00830-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Metabotropic glutamate receptor 3,serine/threonine-protein kinase mtor (112 kDa, Protein from Homo sapiens)
- Metabotropic glutamate receptor 2,peptidyl-prolyl cis-trans isomerase fkbp1a (109 kDa, Protein from Homo sapiens)
- Mglu2-3 heterodimer in presence of ly341495 (Complex from Homo sapiens)
- 2-[(1s,2s)-2-carboxycyclopropyl]-3-(9h-xanthen-9-yl)-d-alanine (353 Da, Ligand)