SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8heb
Q-score: 0.379
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hec
Q-score: 0.358
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8hed
Q-score: 0.469
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein rbd complex with 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 spike glycoprotein rbd (Complex from Oryctolagus cuniculus)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8h00
Q-score: 0.484
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8h01
Q-score: 0.342
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7xbw
Q-score: 0.468
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q
Sci Adv (2022) 8 pp. eabn8048-eabn8048 [ DOI: doi:10.1126/sciadv.abn8048 Pubmed: 35767622 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Chemokine receptor cx3cr1 in complex with gi1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cx3c chemokine receptor 1 (41 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xbx
Q-score: 0.361
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q
Sci Adv (2022) 8 pp. eabn8048-eabn8048 [ DOI: doi:10.1126/sciadv.abn8048 Pubmed: 35767622 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemokine receptor cx3cr1 in complex with cx3cl1 gi1 (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Processed fractalkine,cx3c chemokine receptor 1 (51 kDa, Protein from Homo sapiens)
Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7e9g
Q-score: 0.39
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, Liu J, Yang D, Wang MW, Zhao Q, Wu B
Nature (2021) 594 pp. 583-588 [ DOI: doi:10.1038/s41586-021-03495-2 Pubmed: 34135510 ]
- Dn13 (13 kDa, Protein from Lama glama)
- 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one (344 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Complex of mglu2 homodimer with heterotrimeric gi1 protein in presence of antibodies (Complex from Homo sapiens)
- Metabotropic glutamate receptor 2 (90 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- (1s,2s,5r,6s)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (185 Da, Ligand)
Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu4
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7e9h
Q-score: 0.303
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, Liu J, Yang D, Wang MW, Zhao Q, Wu B
Nature (2021) 594 pp. 583-588 [ DOI: doi:10.1038/s41586-021-03495-2 Pubmed: 34135510 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-3 (40 kDa, Protein from Homo sapiens)
- Complex of mglu4 homodimer with heterotrimeric gi3 protein in presence of antibody (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Metabotropic glutamate receptor 4 (99 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Phosphoserine (185 Da, Ligand)
- Scfv16 (27 kDa, Protein from Homo sapiens)