Electron Microscopy Data Bank

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The structure of the core of the pyruvate dehydrogenase complex in the mitochondria of pig hearts.

Release date: Feb. 5, 2025
Resolution: 4.3 Å
EM Method: Subtomogram averaging

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

The structure of the core of the pyruvate dehydrogenase complex in the mitochondria of pig hearts (Complex from Sus scrofa)

EMD-38716

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The conformation of E3 with PSBD in E2 components of pyruvate dehydrogenase complex

Release date: Feb. 5, 2025
Resolution: 15.0 Å
EM Method: Subtomogram averaging

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

The conformation of e3 with psbd in e2 components of pyruvate dehydrogenase complex (Complex from Sus scrofa)

EMD-61080

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Endogenous dihydrolipoamide acetyltransferase (E2) core of pyruvate dehydrogenase complex from pig heart

Release date: Feb. 5, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9j1w
Q-score: 0.543

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

Dihydrolipoamide acetyltransferase (e2) core (Tissue from Sus scrofa)
Acetyltransferase component of pyruvate dehydrogenase complex (69 kDa, Protein from Sus scrofa)

EMD-61081

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The map of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2

Release date: Feb. 5, 2025
Resolution: 8.7 Å
EM Method: Subtomogram averaging

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

The conformation of e1 with psbd in e2 components of pyruvate dehydrogenase complex (Complex from Sus scrofa)

EMD-61082

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The map of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain and lipoyl domain of E2

Release date: Feb. 5, 2025
Resolution: 8.2 Å
EM Method: Subtomogram averaging

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

Conformation of e1 with psbd and ld in e2 components of pyruvate dehydrogenase complex (Complex from Sus scrofa)

EMD-61083

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The trimer of the pyruvate dehydrogenase complex core

Release date: Feb. 5, 2025
Resolution: 6.2 Å
EM Method: Subtomogram averaging

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

The trimer of the pyruvate dehydrogenase complex core (Complex from Sus scrofa)

EMD-61084

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The conformation of lipoy domain binding the core of the pyruvate dehydrogenase complex.

Release date: Feb. 5, 2025
Resolution: 6.9 Å
EM Method: Subtomogram averaging

Wang C, Ma C, Xu Y, Chang S, Wu H, Yan C, Chen J, Wu Y, An S, Xu J, Han Q, Jiang Y, Jiang Z, Chu X, Gao H, Zhang X, Chang Y

Nat Commun (2025) 16 pp. 917-917 [ DOI: doi:10.1038/s41467-025-56171-8 Pubmed: 39843418 ]

Sample:

The conformation of ld binding the core of the pyruvate dehydrogenase complex. (Complex from Sus scrofa)

EMD-33247

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Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25

Release date: Feb. 22, 2023
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7xk8
Q-score: 0.375

Zhao W, Zhang W, Wang M, Lu M, Chen S, Tang T, Schnapp G, Wagner H, Brennauer A, Yi C, Chu X, Han S, Wu B, Zhao Q

Nat Commun (2022) 13 pp. 7955-7955 [ Pubmed: 36575163 DOI: doi:10.1038/s41467-022-34814-4 ]

Sample:

Neuromedin-u-25 (3 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
Nmu25-nmu2-gi1 complex (Complex from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Neuromedin-u receptor 2 (44 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)

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EMD-32858

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Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1

Release date: April 13, 2022
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wvu
Q-score: 0.434

Zhu Y, Lin X, Zong X, Han S, Wang M, Su Y, Ma L, Chu X, Yi C, Zhao Q, Wu B

Nat Commun (2022) 13 pp. 1775-1775 [ DOI: doi:10.1038/s41467-022-29361-x Pubmed: 35365641 ]

Sample:

Formyl peptide receptor 1 in complex with fmlf and gi1 (Complex from Homo sapiens)
Fme-leu-phe (437 Da, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
Fmet-leu-phe receptor (40 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)

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EMD-32859

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Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2

Release date: April 13, 2022
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7wvv
Q-score: 0.498

Zhu Y, Lin X, Zong X, Han S, Wang M, Su Y, Ma L, Chu X, Yi C, Zhao Q, Wu B

Nat Commun (2022) 13 pp. 1775-1775 [ DOI: doi:10.1038/s41467-022-29361-x Pubmed: 35365641 ]

Sample:

Formyl peptide receptor 2 in complex with fmlfii and gi2 (Complex from Homo sapiens)
Guanine nucleotide-binding protein g(i) subunit alpha-2 (40 kDa, Protein from Homo sapiens)
Fme-leu-phe-ile-ile (663 Da, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Soluble cytochrome b562,n-formyl peptide receptor 2 (56 kDa, Protein from Homo sapiens)

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