Tetrameric 5-HT3A receptor in Salipro (apo, asymmetric)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8c1w
Q-score: 0.366
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ DOI: doi:10.1038/s44318-024-00191-5 Pubmed: 39232129 ]
- Tetrameric 5-ht3ar receptor in salipro (apo, asymmetric) (220 kDa, Complex from Mus musculus)
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
Tetrameric 5-HT3aR in Salipro (apo state, symmetric)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8c1z
Q-score: 0.399
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ DOI: doi:10.1038/s44318-024-00191-5 Pubmed: 39232129 ]
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
- Tetrameric 5-ht3a receptor in salipro (apo, symmetric) (220 kDa, Complex from Mus musculus)
Tetrameric 5-HT3aR in Salipro (holo state, symmetric)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8c20
Q-score: 0.376
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ DOI: doi:10.1038/s44318-024-00191-5 Pubmed: 39232129 ]
- Tetrameric 5-ht3a receptor in salipro (holo, symmetric) (220 kDa, Complex from Mus musculus)
- Serotonin (176 Da, Ligand)
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
Tetrameric 5-HT3A receptor in Salipro (holo, asymmetric)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8c21
Q-score: 0.406
Introini B, Cui W, Chu X, Zhang Y, Alves AC, Eckhardt-Strelau L, Golusik S, Tol M, Vogel H, Yuan S, Kudryashev M
EMBO J (2024) 43 pp. 4451-4471 [ DOI: doi:10.1038/s44318-024-00191-5 Pubmed: 39232129 ]
- Tetrameric 5-ht3ar receptor in salipro (holo, asymmetric) (220 kDa, Complex from Mus musculus)
- 5-hydroxytryptamine receptor 3a (60 kDa, Protein from Mus musculus)
- Serotonin (176 Da, Ligand)
Structural insights into the activation mechanism of antimicrobial GBP1: Polymeric assembly of GBP1
Weismehl M, Chu X, Kutsch M, Lauterjung P, Herrmann C, Kudryashev M, Daumke O
EMBO J (2024) 43 pp. 615-636 [ Pubmed: 38267655 DOI: doi:10.1038/s44318-023-00023-y ]
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8heb
Q-score: 0.379
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hec
Q-score: 0.358
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8hed
Q-score: 0.469
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein rbd complex with 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 spike glycoprotein rbd (Complex from Oryctolagus cuniculus)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8gzz
Q-score: 0.491
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8h00
Q-score: 0.484
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)