cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7np3
Q-score: 0.419
Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A
Mol Cell (2021) 81 pp. 2929-2943.e6 [ DOI: doi:10.1016/j.molcel.2021.05.033 Pubmed: 34166608 ]
cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7np4
Q-score: 0.451
Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A
Mol Cell (2021) 81 pp. 2929-2943.e6 [ DOI: doi:10.1016/j.molcel.2021.05.033 Pubmed: 34166608 ]
Rabbit HCN4 stabilised in amphipol A8-35
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7nmn
Q-score: 0.459
Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A
Mol Cell (2021) 81 pp. 2929- [ DOI: doi:10.1016/j.molcel.2021.05.033 Pubmed: 34166608 ]
Human WLS in complex with WNT8A
Nygaard R, Jia Y, Kim J, Ross D, Parisi G, Clarke OB, Virshup DM, Mancia F
Cell (2020) 184 pp. 194-206.e14 [ Pubmed: 33357447 DOI: 10.1016/j.cell.2020.11.038 ]
Image sets:
Human WLS in complex with WNT8A
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 7kc4
Q-score: 0.506
Nygaard R, Yu J, Kim J, Ross DR, Parisi G, Clarke OB, Virshup DM, Mancia F
Cell (2021) 184 pp. 194- [ DOI: doi:10.1016/j.cell.2020.11.038 Pubmed: 33357447 ]
- 1-cis-9-octadecanoyl-2-cis-9-hexadecanoyl phosphatidyl glycerol (746 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Protein wntless homolog (65 kDa, Protein from Homo sapiens)
- Protein wnt-8a (40 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Complex of wls/evi and wnt8a in nanodisc (105 kDa, Complex from Homo sapiens)
Single-Particle Cryo-EM of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S
Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosário AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalão MJ, Pimentel M, Clarke OB, Lowary TL, Archer M, Niederweis M, Potter CS, Carragher B, Mancia F
Mol. Cell (2020) [ Pubmed: 32386575 DOI: 10.1016/j.molcel.2020.04.014 ]
Image sets:
Single-Particle Cryo-EM of Arabinofuranosyltransferase AftD from Mycobacteria, Wild-type
Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosário AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalão MJ, Pimentel M, Clarke OB, Lowary TL, Archer M, Niederweis M, Potter CS, Carragher B, Mancia F
Mol. Cell (2020) [ Pubmed: 32386575 DOI: 10.1016/j.molcel.2020.04.014 ]
Image sets:
Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6w98
Q-score: 0.535
Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosario AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalao MJ, Pimentel M, Clarke OB, Lowary TL, Archer M, Niederweis M, Potter CS, Carragher B, Mancia F
Mol Cell (2020) 78 pp. 683- [ DOI: doi:10.1016/j.molcel.2020.04.014 Pubmed: 32386575 ]
- Water (18 Da, Ligand)
- Acyl carrier protein (Cellular component from Escherichia coli (strain K12))
- Acyl carrier protein (8 kDa, Protein from Escherichia coli (strain K12))
- F5/8 type c domain-containing protein (149 kDa, Protein from Mycobacteroides abscessus subsp. abscessus)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- F5/8 type c domain-containing protein (Complex from Mycobacteroides abscessus subsp. abscessus)
- Calcium ion (40 Da, Ligand)
- Wild-type mycobacterial arabinofuranosyltransferase aftd complexed with acyl carrier protein (50 kDa, Cellular component)
- 4'-phosphopantetheine (358 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6wbx
Q-score: 0.518
Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosario AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalao MJ, Pimentel M, Clarke OB, Lowary TL, Archer M, Niederweis M, Potter CS, Carragher B, Mancia F
Mol Cell (2020) 78 pp. 683- [ DOI: doi:10.1016/j.molcel.2020.04.014 Pubmed: 32386575 ]
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6wby
Q-score: 0.533
Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosario AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalao MJ, Pimentel M, Clarke OB, Lowary TL, Archer M, Niederweis M, Potter CS, Carragher B, Mancia F
Mol Cell (2020) 78 pp. 683- [ DOI: doi:10.1016/j.molcel.2020.04.014 Pubmed: 32386575 ]