AMC018 SOSIP.v4.2 in complex with PGV04 Fab
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 7rsn
Q-score: 0.447
Schorcht A, Cottrell CA, Pugach P, Ringe RP, Han AX, Allen JD, van den Kerkhof TLGM, Seabright GE, Schermer EE, Ketas TJ, Burger JA, van Schooten J, LaBranche CC, Ozorowski G, de Val N, Bader DLV, Schuitemaker H, Russell CA, Montefiori DC, van Gils MJ, Crispin M, Klasse PJ, Ward AB, Moore JP, Sanders RW
J Virol (2022) 96 pp. e0155221-e0155221 [ Pubmed: 34669426 DOI: doi:10.1128/JVI.01552-21 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Amc018 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Amc018 gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Pgv04 kappa chain (23 kDa, Protein from Homo sapiens)
- Amc018 sosip.v4.2 in complex with pgv04 fab (Complex from Human immunodeficiency virus 1)
- Pgv04 fab heavy chain (24 kDa, Protein from Homo sapiens)
AMC016 SOSIP.v4.2 in complex with PGV04 Fab
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7rso
Q-score: 0.349
Schorcht A, Cottrell CA, Pugach P, Ringe RP, Han AX, Allen JD, van den Kerkhof TLGM, Seabright GE, Schermer EE, Ketas TJ, Burger JA, van Schooten J, LaBranche CC, Ozorowski G, de Val N, Bader DLV, Schuitemaker H, Russell CA, Montefiori DC, van Gils MJ, Crispin M, Klasse PJ, Ward AB, Moore JP, Sanders RW
J Virol (2022) 96 pp. e0155221-e0155221 [ Pubmed: 34669426 DOI: doi:10.1128/JVI.01552-21 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Amc016 sosip.v4.2 in complex with pgv04 fab (Complex from Human immunodeficiency virus 1)
- Pgv04 kappa chain (23 kDa, Protein from Homo sapiens)
- Amc016 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Amc016 gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Pgv04 fab heavy chain (24 kDa, Protein from Homo sapiens)
BG505 SOSIPv5.2 in complex with PGT122 and two RM20E1 Fabs
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ Pubmed: 33826885 DOI: doi:10.1016/j.celrep.2021.108933 ]
BG505 SOSIPv5.2 in complex with PGT122 and three RM20E1 Fabs
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ Pubmed: 33826885 DOI: doi:10.1016/j.celrep.2021.108933 ]
C3 symmetric BG505 SOSIPv5.2 in complex with PGT122 and three RM20E1 Fabs
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ Pubmed: 33826885 DOI: doi:10.1016/j.celrep.2021.108933 ]
BG505 SOSIPv5.2 in complex with PGT122 and one RM20E1 Fab
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ Pubmed: 33826885 DOI: doi:10.1016/j.celrep.2021.108933 ]
BG505 SOSIPv5.2 in complex with PGT122 and no RM20E1 Fabs
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ Pubmed: 33826885 DOI: doi:10.1016/j.celrep.2021.108933 ]
C3 symmetric BG505 SOSIPv5.2 in complex with PGT122 and no RM20E1 Fabs
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ Pubmed: 33826885 DOI: doi:10.1016/j.celrep.2021.108933 ]
Negative stain EM reconstruction of HIV-1 Env AMC008 SOSIP.v4 in complex with Fabs 35O22 and PGV04
de Taeye SW, Ozorowski G, Torrents de la Pena A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW
Cell (2015) 163 pp. 1702-1715 [ Pubmed: 26687358 DOI: doi:10.1016/j.cell.2015.11.056 ]
- Hiv-1 amc008 env sosip.v4 (420 kDa, Protein from Human immunodeficiency virus 1)
- Anti-hiv-1 antibody pgv04 fab (50 kDa, Protein from Homo sapiens)
- Hiv-1 env amc008 sosip.v4 in complex with broadly neutralizing antibody fabs 35o22 and pgv04 (720 kDa, Sample)
- Anti-hiv-1 antibody 35o22 fab (50 kDa, Protein from Homo sapiens)