Structure of y+LAT1 bound with Leu
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8xxi
Q-score: 0.55
To Be Published
- Leucine (131 Da, Ligand)
- Structure of the y+lat1 bound with leu (Complex from Homo sapiens)
- Y+l amino acid transporter 1 (57 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
Structure of y+LAT1 bound with Lys
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8xyj
Q-score: 0.52
To Be Published
- Lysine (147 Da, Ligand)
- Structure of the y+lat1 bound with lys (Complex from Homo sapiens)
- Y+l amino acid transporter 1 (57 kDa, Protein from Homo sapiens)
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8yak
Q-score: 0.652
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- (2~{s})-2-[[(3~{r})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (403 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
- Pwadh-g88d-d344n (Complex from Pseudoxanthomonas wuyuanensis)
Cryo-electron microscopic structure of an amide hydrolase from Pseudoxanthomonas wuyuanensis
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8yag
Q-score: 0.665
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- Zinc ion (65 Da, Ligand)
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
- Pwadh (Complex from Pseudoxanthomonas wuyuanensis)
Cryo-EM structure of ACE2-SIT1 complex with tiagabine
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 8wm3
Q-score: 0.366
Broer A, Hu Z, Kukulowicz J, Yadav A, Zhang T, Dai L, Bajda M, Yan R, Broer S
J Biol Chem (2024) 300 pp. 107687-107687 [ Pubmed: 39159813 DOI: doi:10.1016/j.jbc.2024.107687 ]
- Angiotensin-converting enzyme 2 (94 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sodium- and chloride-dependent transporter xtrp3 (68 kDa, Protein from Homo sapiens)
- Tiagabine (375 Da, Ligand)
- Ace2-sit1 compelx with tiagabine (Complex from Homo sapiens)
Cryo-EM structure of ACE2-B0AT1 complex with JX98
Xu J, Hu Z, Dai L, Yadav A, Jiang Y, Broer A, Gardiner MG, McLeod M, Yan R, Broer S
Nat Commun (2024) 15 pp. 7224-7224 [ Pubmed: 39174516 DOI: doi:10.1038/s41467-024-51748-1 ]
- Sodium-dependent neutral amino acid transporter b(0)at1 (72 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ace2-b0at1 complex with inhibitor jx98 (Complex from Homo sapiens)
- 2-(4-chloranyl-3,5-dimethyl-phenoxy)-~{n}-propan-2-yl-ethanamide (255 Da, Ligand)
- Angiotensin-converting enzyme 2 (94 kDa, Protein from Homo sapiens)
Cryo-EM structure of ACE2-B0AT1 complex with JX225
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8wbz
Q-score: 0.466
Xu J, Hu Z, Dai L, Yadav A, Jiang Y, Broer A, Gardiner MG, McLeod M, Yan R, Broer S
Nat Commun (2024) 15 pp. 7224-7224 [ Pubmed: 39174516 DOI: doi:10.1038/s41467-024-51748-1 ]
- Sodium-dependent neutral amino acid transporter b(0)at1 (72 kDa, Protein from Homo sapiens)
- 2-(4-bromanyl-3-methyl-phenoxy)-~{n}-propyl-ethanamide (286 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme 2 (94 kDa, Protein from Homo sapiens)
- Ace2-b0at1 complex with inhibitor jx225 (Complex from Homo sapiens)
Structural basis for the nucleosome binding and chromatin compaction by the linker histone H5
Structural basis for the nucleosome binding and chromatin compaction by the linker histone H5