Structure of y+LAT1 bound with Leu
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8xxi
Q-score: 0.55
To Be Published
- Sodium ion (22 Da, Ligand)
- Structure of the y+lat1 bound with leu (Complex from Homo sapiens)
- Leucine (131 Da, Ligand)
- Y+l amino acid transporter 1 (57 kDa, Protein from Homo sapiens)
Structure of y+LAT1 bound with Lys
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8xyj
Q-score: 0.52
To Be Published
- Y+l amino acid transporter 1 (57 kDa, Protein from Homo sapiens)
- Lysine (147 Da, Ligand)
- Structure of the y+lat1 bound with lys (Complex from Homo sapiens)
Cryo-EM structure of ACE2-SIT1 complex with tiagabine
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 8wm3
Q-score: 0.366
Broer A, Hu Z, Kukulowicz J, Yadav A, Zhang T, Dai L, Bajda M, Yan R, Broer S
J Biol Chem (2024) 300 pp. 107687-107687 [ DOI: doi:10.1016/j.jbc.2024.107687 Pubmed: 39159813 ]
- Tiagabine (375 Da, Ligand)
- Sodium- and chloride-dependent transporter xtrp3 (68 kDa, Protein from Homo sapiens)
- Ace2-sit1 compelx with tiagabine (Complex from Homo sapiens)
- Angiotensin-converting enzyme 2 (94 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of ACE2-B0AT1 complex with JX98
Xu J, Hu Z, Dai L, Yadav A, Jiang Y, Broer A, Gardiner MG, McLeod M, Yan R, Broer S
Nat Commun (2024) 15 pp. 7224-7224 [ Pubmed: 39174516 DOI: doi:10.1038/s41467-024-51748-1 ]
- Angiotensin-converting enzyme 2 (94 kDa, Protein from Homo sapiens)
- Sodium-dependent neutral amino acid transporter b(0)at1 (72 kDa, Protein from Homo sapiens)
- Ace2-b0at1 complex with inhibitor jx98 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 2-(4-chloranyl-3,5-dimethyl-phenoxy)-~{n}-propan-2-yl-ethanamide (255 Da, Ligand)
Cryo-EM structure of ACE2-B0AT1 complex with JX225
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8wbz
Q-score: 0.466
Xu J, Hu Z, Dai L, Yadav A, Jiang Y, Broer A, Gardiner MG, McLeod M, Yan R, Broer S
Nat Commun (2024) 15 pp. 7224-7224 [ Pubmed: 39174516 DOI: doi:10.1038/s41467-024-51748-1 ]
- Angiotensin-converting enzyme 2 (94 kDa, Protein from Homo sapiens)
- Ace2-b0at1 complex with inhibitor jx225 (Complex from Homo sapiens)
- Sodium-dependent neutral amino acid transporter b(0)at1 (72 kDa, Protein from Homo sapiens)
- 2-(4-bromanyl-3-methyl-phenoxy)-~{n}-propyl-ethanamide (286 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structural basis for the nucleosome binding and chromatin compaction by the linker histone H5
Structural basis for the nucleosome binding and chromatin compaction by the linker histone H5
Structural basis for the linker histone H5-nucleosome binding and chromatin compaction
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8xjv
Q-score: 0.424
Li W, Hu J, Song F, Yu J, Peng X, Zhang S, Wang L, Hu M, Liu JC, Wei Y, Xiao X, Li Y, Li D, Wang H, Zhou BR, Dai L, Mou Z, Zhou M, Zhang H, Zhou Z, Zhang H, Bai Y, Zhou JQ, Li W, Li G, Zhu P
Cell Res (2024) 34 pp. 707-724 [ DOI: doi:10.1038/s41422-024-01009-z Pubmed: 39103524 ]
- Histone h2a (14 kDa, Protein from Xenopus laevis)
- Histone h4 (Complex from Xenopus laevis)
- Histone h2b (Complex from Xenopus laevis)
- Linker histone h5 (Complex from Gallus gallus)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h5 (21 kDa, Protein from Gallus gallus)
- Dna (660 kDa, DNA from synthetic construct)
- 12x177bp-h5 chromatin (Complex)
- Dna (651 kDa, DNA from synthetic construct)
- Histone h3.1 (Complex from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Widom 601 dna (Complex from synthetic construct)
- Histone h2a (Complex from Xenopus laevis)
Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8xxw
Q-score: 0.484
Liu C, Xu S, Zheng Y, Xie Y, Xu K, Chai Y, Luo T, Dai L, Gao GF
Cell Rep (2024) 43 pp. 114235-114235 [ Pubmed: 38748880 DOI: doi:10.1016/j.celrep.2024.114235 ]
- Fab (Complex from Mus musculus)
- Ace2 (Complex from Homo sapiens)
- Spike protein s1 (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M2-7-light chain (12 kDa, Protein from Mus musculus)
- Zinc ion (65 Da, Ligand)
- M2-7-heavy chain (13 kDa, Protein from Mus musculus)
- Fab m2-7 complexed with sars-cov2 rbd and human ace2 (Complex)
- Rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Processed angiotensin-converting enzyme 2 (67 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)